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trpA trpA rlmN rlmN KTR00308.1 KTR00308.1 pdxS pdxS KTR11771.1 KTR11771.1 KTR10921.1 KTR10921.1 deoC deoC KTR10014.1 KTR10014.1 KTR09800.1 KTR09800.1 moaA moaA KTR09517.1 KTR09517.1 KTR09199.1 KTR09199.1 KTR09072.1 KTR09072.1 KTR08938.1 KTR08938.1 KTR08945.1 KTR08945.1 KTR08756.1 KTR08756.1 KTR08747.1 KTR08747.1 dapA dapA trpF trpF KTR07973.1 KTR07973.1 guaB guaB KTR07783.1 KTR07783.1 KTR07751.1 KTR07751.1 KTR07124.1 KTR07124.1 KTR06997.1 KTR06997.1 KTR06848.1 KTR06848.1 leuA leuA KTR06429.1 KTR06429.1 pyrD pyrD KTR06076.1 KTR06076.1 KTR06079.1 KTR06079.1 KTR04581.1 KTR04581.1 tal tal tpiA tpiA KTR04350.1 KTR04350.1 KTR04139.1 KTR04139.1 KTR03818.1 KTR03818.1 hisF hisF KTR03779.1 KTR03779.1 KTR03825.1 KTR03825.1 lipA lipA KTR03500.1 KTR03500.1 KTR03153.1 KTR03153.1 thiE thiE KTR02424.1 KTR02424.1 KTR02113.1 KTR02113.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa)
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (410 aa)
KTR00308.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (306 aa)
KTR11771.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
KTR10921.1Alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (242 aa)
KTR10014.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (333 aa)
KTR09800.13-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
moaAMolybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (352 aa)
KTR09517.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
KTR09199.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (384 aa)
KTR09072.1Triosephosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
KTR08938.1Deoxyribose-phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
KTR08945.1Transaldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
KTR08756.1Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (283 aa)
KTR08747.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (325 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (207 aa)
KTR07973.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (416 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
KTR07783.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
KTR07751.1Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family. (518 aa)
KTR07124.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
KTR06997.11,2-oxophytodienoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KTR06848.1N-acetylneuraminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (591 aa)
KTR06429.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (411 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (335 aa)
KTR06076.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa)
KTR06079.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1136 aa)
KTR04581.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (370 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
KTR04350.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
KTR04139.1GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. (1862 aa)
KTR03818.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
KTR03779.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
KTR03825.1Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa)
KTR03500.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
KTR03153.12-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (227 aa)
KTR02424.1Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
KTR02113.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1535 aa)
Your Current Organism:
Curtobacterium luteum
NCBI taxonomy Id: 33881
Other names: ATCC 15830, Brevibacterium luteum, C. luteum, CCUG 23848, CIP 102694, Curtibacterium luteum, DSM 20542, IFO 12676, LMG 8787, LMG:8787, NBRC 12676
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