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KTR09184.1 KTR09184.1 KTR08224.1 KTR08224.1 mqo mqo KTR06079.1 KTR06079.1 KTR08225.1 KTR08225.1 sucD sucD sucC sucC acnA acnA kgd kgd KTR03395.1 KTR03395.1 KTR03368.1 KTR03368.1 KTR03367.1 KTR03367.1 KTR03366.1 KTR03366.1 KTR04382.1 KTR04382.1 KTR04671.1 KTR04671.1 KTR11678.1 KTR11678.1 KTR11762.1 KTR11762.1 KTR11679.1 KTR11679.1 pckG pckG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KTR09184.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (914 aa)
KTR08224.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
KTR06079.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1136 aa)
KTR08225.1Dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
acnAAconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (945 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1255 aa)
KTR03395.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
KTR03368.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
KTR03367.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
KTR03366.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (257 aa)
KTR04382.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
KTR04671.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (419 aa)
KTR11678.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
KTR11762.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
KTR11679.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (626 aa)
Your Current Organism:
Curtobacterium luteum
NCBI taxonomy Id: 33881
Other names: ATCC 15830, Brevibacterium luteum, C. luteum, CCUG 23848, CIP 102694, Curtibacterium luteum, DSM 20542, IFO 12676, LMG 8787, LMG:8787, NBRC 12676
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