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| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (117 aa) |
| | A6122_0184 | rRNA methyltransferase. (217 aa) |
| | rnj | Ribonuclease; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (568 aa) |
| | glyQS | glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (463 aa) |
| | A6122_0414 | Hypothetical protein; Belongs to the UPF0176 family. (299 aa) |
| | A6122_0453 | RNA helicase. (679 aa) |
| | A6122_0490 | Plasmid stabilization protein. (86 aa) |
| | A6122_0526 | RNA polymerase subunit sigma-70; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa) |
| | A6122_0546 | DEAD/DEAH box helicase. (515 aa) |
| | A6122_2792 | Hypothetical protein. (88 aa) |
| | A6122_2876 | Hypothetical protein. (195 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (457 aa) |
| | A6122_2916 | CCA tRNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (474 aa) |
| | rsmG | 16S rRNA methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (209 aa) |
| | deaD | Cold-shock protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (593 aa) |
| | A6122_2702 | Hypothetical protein. (291 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (363 aa) |
| | lysS | lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (526 aa) |
| | A6122_2424 | Hypothetical protein. (362 aa) |
| | aspS | aspartate--tRNA(Asn) ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (451 aa) |
| | A6122_2353 | Hypothetical protein. (123 aa) |
| | nusG | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (325 aa) |
| | A6122_2132 | rRNA methyltransferase. (267 aa) |
| | A6122_2123 | Hypothetical protein. (282 aa) |
| | A6122_2043 | Hypothetical protein. (125 aa) |
| | A6122_2028 | RNA polymerase subunit sigma; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa) |
| | rnhA | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (173 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa) |
| | A6122_1951 | 23S rRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (434 aa) |
| | A6122_1878 | Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (265 aa) |
| | A6122_1761 | Hypothetical protein. (451 aa) |
| | argS | arginine--tRNA ligase. (526 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (778 aa) |
| | A6122_1729 | threonylcarbamoyl-AMP synthase; Belongs to the SUA5 family. (331 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (588 aa) |
| | nusA | Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (341 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (145 aa) |
| | truB | tRNA pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (315 aa) |
| | A6122_1664 | Hypothetical protein; Belongs to the SUA5 family. (213 aa) |
| | A6122_1662 | Translation factor Sua5; Belongs to the SUA5 family. (259 aa) |
| | A6122_1644 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. (206 aa) |
| | leuS | leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | A6122_1592 | 16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (248 aa) |
| | ybeY | rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (153 aa) |
| | A6122_1577 | Hypothetical protein. (165 aa) |
| | A6122_1576 | tRNA-dihydrouridine synthase. (408 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (619 aa) |
| | A6122_1566 | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (370 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (250 aa) |
| | rimM | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (219 aa) |
| | trmD | tRNA (guanine(37)-N(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (227 aa) |
| | A6122_1488 | Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa) |
| | A6122_1471 | Hypothetical protein. (78 aa) |
| | ybaK | aminoacyl-tRNA deacylase; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (160 aa) |
| | mnmA | tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (367 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (214 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (851 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1109 aa) |
| | A6122_1399 | Ribonuclease G. (900 aa) |
| | sigA | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (439 aa) |
| | A6122_1355 | Ribonuclease D. (399 aa) |
| | A6122_1307 | RNA helicase. (812 aa) |
| | A6122_1300 | SAM-dependent methyltransferase. (342 aa) |
| | A6122_1278 | rRNA methyltransferase. (269 aa) |
| | A6122_1224 | CarD family transcriptional regulator. (163 aa) |
| | A6122_1204 | Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (457 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (301 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (84 aa) |
| | nusB | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa) |
| | A6122_1180 | Crossover junction endodeoxyribonuclease RuvA; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (194 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (885 aa) |
| | thrS | threonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (667 aa) |
| | A6122_1129 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (307 aa) |
| | rsmH | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (327 aa) |
| | A6122_1045 | MFS transporter; Belongs to the pseudouridine synthase RsuA family. (315 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (436 aa) |
| | pheT | phenylalanine--tRNA ligase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (843 aa) |
| | pheS | phenylalanine--tRNA ligase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (424 aa) |
| | A6122_1019 | RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (266 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (321 aa) |
| | miaB | tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (534 aa) |
| | rnj-2 | Ribonuclease; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (558 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (752 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (514 aa) |
| | A6122_0942 | D-beta-D-heptose 1-phosphate adenosyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (457 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (253 aa) |
| | A6122_0847 | RNA helicase; Belongs to the DEAD box helicase family. (472 aa) |
| | A6122_0846 | Metal-dependent phosphoesterase. (300 aa) |
| | A6122_0816 | histidine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (427 aa) |
| | rsmA | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (332 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (528 aa) |
| | rsmI | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (273 aa) |
| | A6122_0787 | ATP-dependent RNA helicase HrpA. (1304 aa) |
| | A6122_0739 | Lipopolysaccharide kinase. (438 aa) |
| | A6122_0738 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (339 aa) |
| | cysS | cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa) |
| | A6122_0735 | CarD family transcriptional regulator. (160 aa) |
| | A6122_0714 | RNA polymerase subunit sigma; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa) |
| | A6122_0702 | aminoacyl-tRNA deacylase. (163 aa) |
| | A6122_0697 | Hypothetical protein. (157 aa) |
| | tsaD | N(6)-L-threonylcarbamoyladenine synthase TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (354 aa) |
| | A6122_0623 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB. (206 aa) |
| | A6122_0622 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (166 aa) |
| | truA | tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (297 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (328 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1299 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1163 aa) |
