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| | KZE19101.1 | Coenzyme A pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | KZE20176.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa) |
| | KZE20174.1 | (p)ppGpp synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | KZE20162.1 | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa) |
| | KZE20141.1 | Molybdenum cofactor sulfurylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa) |
| | KZE20136.1 | Cyclic amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa) |
| | KZE20206.1 | OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | KZE20133.1 | 5-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (107 aa) |
| | KZE20132.1 | Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (294 aa) |
| | KZE20205.1 | Alpha-ketoglutarate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa) |
| | KZE20128.1 | (S)-ureidoglycine aminohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa) |
| | KZE20204.1 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (216 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | nadD | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | KZE20846.1 | acyl-CoA thioesterase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (437 aa) |
| | KZE20831.1 | ATP synthase F0F1 subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (483 aa) |
| | atpG | ATP synthase F0F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (310 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (544 aa) |
| | atpH | ATP synthase F0F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (268 aa) |
| | atpF | ATP synthase F0F1 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (183 aa) |
| | atpE | ATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpB | ATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (248 aa) |
| | KZE20807.1 | Guanosine monophosphate reductase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa) |
| | KZE20788.1 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | KZE21715.1 | Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | KZE21673.1 | Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (189 aa) |
| | KZE21637.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | KZE21732.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | KZE21634.1 | Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | prpE | propionate--CoA ligase; Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa) |
| | dcd | dCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (192 aa) |
| | KZE21542.1 | Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa) |
| | KZE21541.1 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | KZE21540.1 | Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa) |
| | KZE21536.1 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (424 aa) |
| | KZE18148.1 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (765 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (325 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa) |
| | KZE18169.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (379 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1091 aa) |
| | KZE18172.1 | Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (287 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (187 aa) |
| | KZE18176.1 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (417 aa) |
| | KZE18187.1 | acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa) |
| | KZE18197.1 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (302 aa) |
| | pgk | Phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (406 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa) |
| | KZE18220.1 | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (539 aa) |
| | KZE15263.1 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa) |
| | tdk | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | KZE09942.1 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa) |
| | KZE09958.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa) |
| | KZE09959.1 | TesB-like acyl-CoA thioesterase 3; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa) |
| | tdk-2 | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa) |
| | KZE09981.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa) |
| | AVW13_03675 | GrpB domain protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa) |
| | KZE18408.1 | MazG family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | KZE18483.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (243 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (84 aa) |
| | purC | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (749 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (493 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | KZE17959.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa) |
| | KZE17697.1 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | AVW13_13700 | Transcriptional regulator; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa) |
| | KZE17677.1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa) |
| | KZE17205.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (113 aa) |
| | KZE17207.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (183 aa) |
| | KZE16138.1 | Alpha-ketoglutarate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (920 aa) |
| | KZE16175.1 | Pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa) |
| | AVW13_15065 | Cytidine deaminase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa) |
| | deoC | 2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (217 aa) |
| | KZE16059.1 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (278 aa) |
| | KZE15980.1 | Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (168 aa) |
| | AVW13_15445 | 5-dehydro-2-deoxygluconokinase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | KZE13414.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa) |
| | AVW13_16200 | Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (132 aa) |
| | KZE11172.1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa) |
| | KZE11169.1 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | AVW13_16900 | Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa) |
| | nadK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (308 aa) |
| | KZE21721.1 | Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (559 aa) |
| | KZE24417.1 | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | cmk | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa) |
| | KZE23432.1 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (188 aa) |
| | KZE23004.1 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (323 aa) |
| | KZE22992.1 | Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) |
| | KZE22895.1 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (261 aa) |
| | KZE22878.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (250 aa) |
| | KZE22794.1 | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (312 aa) |
| | purL | Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...] (783 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | KZE23452.1 | DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (145 aa) |
| | KZE24623.1 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | purU-2 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (281 aa) |
| | KZE24559.1 | Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa) |
| | KZE24560.1 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa) |
| | KZE24561.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (509 aa) |
| | AVW13_08330 | Hypothetical protein; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (508 aa) |
| | KZE22262.1 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (327 aa) |
| | KZE22261.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (545 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (427 aa) |
| | KZE22254.1 | Guanosine monophosphate reductase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (526 aa) |
| | KZE22248.1 | Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | coaA | Pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa) |
| | nnrD | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (522 aa) |
| | KZE22567.1 | Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa) |
| | KZE22531.1 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa) |
| | KZE22458.1 | (p)ppGpp synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa) |
| | KZE22420.1 | Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa) |
| | KZE24568.1 | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (816 aa) |
| | KZE24575.1 | Glutamine amidotransferase class-I; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa) |
| | KZE24586.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | KZE24619.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa) |
| | KZE22109.1 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (225 aa) |
| | KZE22148.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | KZE22151.1 | Phosphoheptose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (179 aa) |
| | KZE22162.1 | Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa) |
| | KZE18267.1 | HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (484 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa) |
| | KZE18389.1 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (201 aa) |
| | KZE18384.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (439 aa) |
| | KZE18380.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (153 aa) |
| | KZE19045.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | KZE19084.1 | Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa) |
| | nadE | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (278 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (925 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa) |
