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Ppro_0033 Ppro_0033 Ppro_0034 Ppro_0034 Ppro_0035 Ppro_0035 Ppro_0074 Ppro_0074 Ppro_0286 Ppro_0286 tal tal Ppro_0298 Ppro_0298 Ppro_0319 Ppro_0319 Ppro_0321 Ppro_0321 Ppro_0322 Ppro_0322 Ppro_0323 Ppro_0323 Ppro_0324 Ppro_0324 Ppro_0325 Ppro_0325 Ppro_0343 Ppro_0343 Ppro_0452 Ppro_0452 Ppro_0469 Ppro_0469 Ppro_0470 Ppro_0470 Ppro_0471 Ppro_0471 Ppro_0472 Ppro_0472 Ppro_0548 Ppro_0548 Ppro_0549 Ppro_0549 ackA ackA Ppro_0642 Ppro_0642 Ppro_0749 Ppro_0749 Ppro_0776 Ppro_0776 Ppro_1046 Ppro_1046 Ppro_1110 Ppro_1110 Ppro_1134 Ppro_1134 accD accD Ppro_1290 Ppro_1290 Ppro_1336 Ppro_1336 pgi pgi pfkA pfkA eno eno Ppro_1692 Ppro_1692 Ppro_1693 Ppro_1693 pgk pgk tpiA tpiA Ppro_1714 Ppro_1714 sucD sucD sucC sucC fbp fbp Ppro_1852 Ppro_1852 Ppro_1853 Ppro_1853 Ppro_2022 Ppro_2022 Ppro_2023 Ppro_2023 accA accA Ppro_2144 Ppro_2144 Ppro_2189 Ppro_2189 Ppro_2214 Ppro_2214 ackA-2 ackA-2 Ppro_2323 Ppro_2323 Ppro_2324 Ppro_2324 Ppro_2325 Ppro_2325 Ppro_2326 Ppro_2326 mdh mdh Ppro_2481 Ppro_2481 Ppro_2482 Ppro_2482 Ppro_2483 Ppro_2483 Ppro_2601 Ppro_2601 Ppro_2845 Ppro_2845 Ppro_2974 Ppro_2974 Ppro_3305 Ppro_3305 Ppro_3466 Ppro_3466 Ppro_3473 Ppro_3473 Ppro_3497 Ppro_3497 Ppro_3511 Ppro_3511 pckA pckA gpmI gpmI
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Ppro_0033Conserved carboxylase region; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: aba:Acid345_3026 conserved carboxylase region. (499 aa)
Ppro_0034PFAM: carboxyl transferase; KEGG: aba:Acid345_3025 carboxyl transferase. (516 aa)
Ppro_0035PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: aba:Acid345_3023 biotin/lipoyl attachment. (129 aa)
Ppro_0074TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: gsu:GSU3395 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (530 aa)
Ppro_0286PFAM: acetyl-CoA hydrolase/transferase; KEGG: gme:Gmet_3044 acetyl-CoA hydrolase/transferase. (531 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
Ppro_0298PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: gsu:GSU0097 pyruvate ferredoxin/flavodoxin oxidoreductase. (1191 aa)
Ppro_0319PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: dps:DP1201 related to pyruvate synthase, subunit PorB. (259 aa)
Ppro_0321KEGG: sat:SYN_02383 phosphoenolpyruvate synthase. (892 aa)
Ppro_0322TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: ctc:CTC02528 pyruvate synthase subunit porC. (191 aa)
Ppro_0323TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: tma:TM0016 pyruvate ferredoxin oxidoreductase, delta subunit. (96 aa)
Ppro_0324Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ctc:CTC02526 pyruvate synthase subunit porA. (396 aa)
Ppro_0325Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: ctc:CTC02525 pyruvate synthase subunit porB. (311 aa)
Ppro_0343KEGG: gme:Gmet_1211 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa)
Ppro_0452TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_1038 isocitrate dehydrogenase. (470 aa)
Ppro_0469PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase, beta subunit. (301 aa)
Ppro_0470PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mta:Moth_1922 pyruvate flavodoxin/ferredoxin oxidoreductase-like. (418 aa)
Ppro_0471TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE3276 2-ketoacid ferredoxin oxidoreductase delta subunit. (105 aa)
Ppro_0472TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tko:TK1978 pyruvate/2-oxoisovalerate: ferredoxin oxidoreductases, common gamma subunit. (188 aa)
Ppro_0548TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mth:MTH537 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (287 aa)
Ppro_0549PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1164 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (576 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (421 aa)
Ppro_0642KEGG: chy:CHY_0443 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (912 aa)
Ppro_0749Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa)
Ppro_0776KEGG: gsu:GSU1818 phosphoglycerate mutase family protein; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein. (398 aa)
Ppro_1046PFAM: aminotransferase, class I and II; KEGG: gsu:GSU1061 aspartate aminotransferase. (398 aa)
Ppro_1110PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: gme:Gmet_0804 alcohol dehydrogenase superfamily, zinc-containing. (331 aa)
Ppro_1134PFAM: Citrate synthase; KEGG: sth:STH2542 citrate synthase; Belongs to the citrate synthase family. (441 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
Ppro_1290Phosphotransacetylase; KEGG: gsu:GSU2706 phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (334 aa)
Ppro_1336Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: gme:Gmet_2458 glucose-6-phosphate isomerase; Belongs to the GPI family. (529 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (429 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
Ppro_1692Aconitase; PFAM: aconitate hydratase domain protein; aconitate hydratase 2; KEGG: gme:Gmet_1912 aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (844 aa)
Ppro_1693KEGG: gme:Gmet_1946 glyceraldehyde-3-phosphate dehydrogenase, type I. (65 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: gsu:GSU1628 phosphoglycerate kinase/triosephosphate isomerase; Belongs to the phosphoglycerate kinase family. (399 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
Ppro_1714KEGG: ftu:FTT1368c glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (394 aa)
fbpPFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: gsu:GSU1651 fructose-1,6-bisphosphatase. (323 aa)
Ppro_1852PFAM: pyruvate kinase; KEGG: sat:SYN_02952 pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
Ppro_1853Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (356 aa)
Ppro_2022acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
Ppro_2023Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
Ppro_2144PFAM: aldehyde dehydrogenase; KEGG: gme:Gmet_0789 aldehyde dehydrogenase. (546 aa)
Ppro_2189L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. (397 aa)
Ppro_2214PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: gme:Gmet_0804 alcohol dehydrogenase superfamily, zinc-containing. (331 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (417 aa)
Ppro_23232-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gsu:GSU1470 keto/oxoacid ferredoxin oxidoreductase, gamma subunit. (185 aa)
Ppro_23242-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: gme:Gmet_1363 ferrodoxin oxidoreductase beta subunit. (273 aa)
Ppro_23252-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gme:Gmet_1362 2-oxoglutarate ferredoxin oxidoreductase. (377 aa)
Ppro_2326PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: gme:Gmet_1361 iron-sulfur cluster-binding protein. (71 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa)
Ppro_2481Succinate dehydrogenase subunit B; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: gme:Gmet_2395 succinate dehydrogenase. (252 aa)
Ppro_2482KEGG: ade:Adeh_2933 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (638 aa)
Ppro_2483TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: gsu:GSU1176 fumarate reductase, cytochrome b subunit, putative. (221 aa)
Ppro_2601Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
Ppro_2845Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
Ppro_2974Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (914 aa)
Ppro_3305KEGG: gsu:GSU1193 ketose-bisphosphate aldolase family protein. (426 aa)
Ppro_3466TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: gsu:GSU0937 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa)
Ppro_3473KEGG: gme:Gmet_2733 cobyrinic acid a,c-diamide synthase family protein. (363 aa)
Ppro_3497Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: gsu:GSU1305 Glu/Leu/Phe/Val dehydrogenase family protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
Ppro_3511KEGG: gsu:GSU0580 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (885 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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