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Ppro_0072 Ppro_0072 Ppro_0184 Ppro_0184 Ppro_0281 Ppro_0281 folD folD def def Ppro_0737 Ppro_0737 lpxC lpxC cheB cheB Ppro_0924 Ppro_0924 Ppro_0979 Ppro_0979 Ppro_1062 Ppro_1062 Ppro_1229 Ppro_1229 Ppro_1596 Ppro_1596 cheB-2 cheB-2 pyrG pyrG ribBA ribBA Ppro_1839 Ppro_1839 Ppro_1980 Ppro_1980 nadE nadE tadA tadA cheD cheD Ppro_2470 Ppro_2470 pyrC pyrC purH purH Ppro_2690 Ppro_2690 Ppro_2826 Ppro_2826 Ppro_2866 Ppro_2866 nadE-2 nadE-2 hisI hisI Ppro_2976 Ppro_2976 hisH hisH folE2 folE2 Ppro_3409 Ppro_3409 Ppro_3453 Ppro_3453 def-2 def-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Ppro_0072PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: pca:Pcar_0660 cytidine and deoxycytidylate deaminase family protein. (204 aa)
Ppro_0184Beta-lactamase; PFAM: penicillin-binding protein, transpeptidase; KEGG: bte:BTH_II0373 beta-lactamase precursor. (288 aa)
Ppro_0281PFAM: protein of unknown function DUF152; KEGG: gsu:GSU0083 conserved hypothetical protein TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. (265 aa)
folDMethenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (172 aa)
Ppro_0737Agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: gsu:GSU1028 peptidylarginine deiminase-related protein; Belongs to the agmatine deiminase family. (341 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (290 aa)
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (358 aa)
Ppro_0924PFAM: polysaccharide deacetylase; KEGG: sha:SH1754 hypothetical protein. (173 aa)
Ppro_0979PFAM: polysaccharide deacetylase; KEGG: gme:Gmet_2850 polysaccharide deacetylase. (284 aa)
Ppro_1062N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: gsu:GSU1821 N-acetylmuramoyl-L-alanine amidase, family 3. (432 aa)
Ppro_1229PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pca:Pcar_0579 carbon-nitrogen hydrolase family protein. (286 aa)
Ppro_15965-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
cheB-2Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (356 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa)
Ppro_1839PFAM: Sel1 domain protein repeat-containing protein; KEGG: nma:NMA0184 hypothetical protein. (361 aa)
Ppro_1980PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: psp:PSPPH_1477 cytosine deaminase. (145 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (689 aa)
tadAtRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (181 aa)
cheDCheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (198 aa)
Ppro_2470PFAM: polysaccharide deacetylase; KEGG: dvu:DVUA0043 polysaccharide deacetylase family protein. (301 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (424 aa)
purHIMP cyclohydrolase; KEGG: gsu:GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase. (521 aa)
Ppro_2690PFAM: phosphoesterase, PA-phosphatase related; KEGG: pca:Pcar_0098 hypothetical protein. (166 aa)
Ppro_2826PFAM: YdjC family protein; KEGG: gme:Gmet_2415 YdjC-like protein. (288 aa)
Ppro_2866Hypothetical protein. (314 aa)
nadE-2NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (332 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (125 aa)
Ppro_2976PFAM: isochorismatase hydrolase; KEGG: dvu:DVU0033 isochorismatase family protein. (190 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (207 aa)
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (276 aa)
Ppro_3409PFAM: amidohydrolase; Amidohydrolase 3; KEGG: gme:Gmet_1645 chlorohydrolase, Atz/Trz family. (428 aa)
Ppro_3453KEGG: gsu:GSU3046 flagellar protein FlgJ-like protein. (123 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (168 aa)
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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