STRINGSTRING
trpB-2 trpB-2 Ppro_1294 Ppro_1294 Ppro_1335 Ppro_1335 Ppro_1336 Ppro_1336 Ppro_1345 Ppro_1345 Ppro_1346 Ppro_1346 aroA aroA ispH ispH pgi pgi hisS hisS Ppro_1413 Ppro_1413 Ppro_1491 Ppro_1491 Ppro_1493 Ppro_1493 Ppro_1514 Ppro_1514 Ppro_1515 Ppro_1515 fabH-2 fabH-2 hisC hisC Ppro_1523 Ppro_1523 Ppro_1524 Ppro_1524 Ppro_1544 Ppro_1544 Ppro_1546 Ppro_1546 Ppro_1550 Ppro_1550 valS valS Ppro_1587 Ppro_1587 gcvH gcvH gcvPA gcvPA Ppro_1593 Ppro_1593 pyrG pyrG kdsA kdsA pfkA pfkA eno eno metG metG Ppro_1669 Ppro_1669 Ppro_1681 Ppro_1681 Ppro_1687 Ppro_1687 pgk pgk tpiA tpiA Ppro_1699 Ppro_1699 asnS asnS selD selD serC serC ispE ispE Ppro_0748 Ppro_0748 Ppro_0776 Ppro_0776 Ppro_0829 Ppro_0829 Ppro_0838 Ppro_0838 Ppro_0869 Ppro_0869 cobQ cobQ Ppro_0905 Ppro_0905 gpmI gpmI ileS ileS nadA nadA panB panB panC panC panD panD Ppro_3511 Ppro_3511 proA proA metXA metXA Ppro_3497 Ppro_3497 gltX gltX Ppro_3483 Ppro_3483 Ppro_3466 Ppro_3466 dapF dapF gluQ gluQ Ppro_3360 Ppro_3360 Ppro_3359 Ppro_3359 Ppro_3345 Ppro_3345 Ppro_3342 Ppro_3342 Ppro_3320 Ppro_3320 tyrS tyrS Ppro_3305 Ppro_3305 mqnB mqnB Ppro_3262 Ppro_3262 Ppro_3253 Ppro_3253 Ppro_3236 Ppro_3236 alaS alaS argB argB argD argD argF argF argG argG argH argH Ppro_3136 Ppro_3136 Ppro_3135 Ppro_3135 Ppro_3103 Ppro_3103 Ppro_3083 Ppro_3083 Ppro_3082 Ppro_3082 argC argC dapA dapA dapB dapB dapL dapL glyQ glyQ glyS glyS hisH hisH hisA hisA hisF hisF hisE hisE hisG-2 hisG-2 hisD hisD hisC-2 hisC-2 hisB hisB fabZ-2 fabZ-2 lysS lysS Ppro_2986 Ppro_2986 ispD ispD proB proB hisG hisG hisI hisI Ppro_2942 Ppro_2942 Ppro_2909 Ppro_2909 Ppro_2894 Ppro_2894 cbiA cbiA Ppro_2887 Ppro_2887 Ppro_2871 Ppro_2871 Ppro_2867 Ppro_2867 Ppro_2845 Ppro_2845 Ppro_2830 Ppro_2830 proC proC Ppro_2815 Ppro_2815 Ppro_2793 Ppro_2793 Ppro_2785 Ppro_2785 Ppro_2772 Ppro_2772 Ppro_2768 Ppro_2768 Ppro_2767 Ppro_2767 Ppro_2754 Ppro_2754 Ppro_2736 Ppro_2736 Ppro_2690 Ppro_2690 Ppro_2669 Ppro_2669 Ppro_2646 Ppro_2646 Ppro_2644 Ppro_2644 speA speA Ppro_2594 Ppro_2594 Ppro_2593 Ppro_2593 ilvD ilvD Ppro_2557 Ppro_2557 Ppro_2556 Ppro_2556 ilvC ilvC Ppro_2550 Ppro_2550 Ppro_2540 Ppro_2540 pyrB pyrB carA carA carB carB Ppro_2520 Ppro_2520 Ppro_2507 Ppro_2507 Ppro_2495 Ppro_2495 Ppro_2466 Ppro_2466 trpF trpF Ppro_2395 Ppro_2395 Ppro_2361 Ppro_2361 aroQ aroQ aroE aroE Ppro_2350 Ppro_2350 Ppro_2334 Ppro_2334 aspS aspS mdh mdh Ppro_2313 Ppro_2313 thrS thrS pheS pheS pheT pheT Ppro_2262 Ppro_2262 acpS acpS Ppro_2253 Ppro_2253 Ppro_2249 Ppro_2249 lipA-2 lipA-2 Ppro_2167 Ppro_2167 Ppro_2166 Ppro_2166 Ppro_2161 Ppro_2161 Ppro_2160 Ppro_2160 bioF bioF bioC bioC accA accA dxr dxr aroC aroC aroB aroB Ppro_2023 Ppro_2023 Ppro_2022 Ppro_2022 gcvH-2 gcvH-2 guaA guaA Ppro_1995 Ppro_1995 Ppro_1952 Ppro_1952 Ppro_1949 Ppro_1949 Ppro_1945 Ppro_1945 Ppro_1743 Ppro_1743 Ppro_1927 Ppro_1927 Ppro_1926 Ppro_1926 Ppro_1853 Ppro_1853 Ppro_1852 Ppro_1852 Ppro_1832 Ppro_1832 Ppro_1831 Ppro_1831 Ppro_1830 Ppro_1830 Ppro_1787 Ppro_1787 Ppro_1765 Ppro_1765 Ppro_1764 Ppro_1764 Ppro_1754 Ppro_1754 proS proS ispG ispG glyA glyA Ppro_1746 Ppro_1746 acpP-2 acpP-2 Ppro_1744 Ppro_1744 Ppro_0907 Ppro_0907 acpP acpP Ppro_0910 Ppro_0910 Ppro_0911 Ppro_0911 Ppro_0915 Ppro_0915 Ppro_0917 Ppro_0917 Ppro_0918 Ppro_0918 Ppro_0923 Ppro_0923 Ppro_0926 Ppro_0926 Ppro_0927 Ppro_0927 Ppro_0928 Ppro_0928 Ppro_0931 Ppro_0931 argS argS Ppro_1022 Ppro_1022 Ppro_1024 Ppro_1024 Ppro_1025 Ppro_1025 Ppro_1026 Ppro_1026 Ppro_1027 Ppro_1027 Ppro_1028 Ppro_1028 lipA lipA Ppro_1041 Ppro_1041 Ppro_1043 Ppro_1043 Ppro_1061 Ppro_1061 Ppro_1079 Ppro_1079 Ppro_1080 Ppro_1080 Ppro_1087 Ppro_1087 Ppro_1089 Ppro_1089 Ppro_1144 Ppro_1144 purF purF Ppro_1160 Ppro_1160 accD accD trpA trpA bioB bioB bioD bioD bioA bioA Ppro_1187 Ppro_1187 Ppro_1192 Ppro_1192 Ppro_1210 Ppro_1210 Ppro_1277 Ppro_1277 trpB trpB ispF ispF fabH fabH cysS cysS Ppro_0034 Ppro_0034 Ppro_0035 Ppro_0035 leuB leuB Ppro_0046 Ppro_0046 Ppro_0047 Ppro_0047 Ppro_0050 Ppro_0050 Ppro_0088 Ppro_0088 glmS glmS Ppro_0132 Ppro_0132 Ppro_0283 Ppro_0283 Ppro_0286 Ppro_0286 Ppro_0296 Ppro_0296 Ppro_0302 Ppro_0302 Ppro_0319 Ppro_0319 Ppro_0321 Ppro_0321 Ppro_0322 Ppro_0322 Ppro_0323 Ppro_0323 Ppro_0324 Ppro_0324 Ppro_0325 Ppro_0325 Ppro_0337 Ppro_0337 Ppro_0338 Ppro_0338 fabZ fabZ Ppro_0364 Ppro_0364 mtnP mtnP Ppro_0452 Ppro_0452 Ppro_0469 Ppro_0469 Ppro_0470 Ppro_0470 Ppro_0471 Ppro_0471 leuA leuA folD folD dtd dtd mtnA mtnA hisZ hisZ Ppro_0550 Ppro_0550 Ppro_0566 Ppro_0566 Ppro_0567 Ppro_0567 Ppro_0579 Ppro_0579 serS serS Ppro_0623 Ppro_0623 leuC leuC Ppro_0642 Ppro_0642 Ppro_0643 Ppro_0643 trpC trpC trpD trpD argJ argJ Ppro_0729 Ppro_0729 Ppro_0734 Ppro_0734 Ppro_1713 Ppro_1713 glnS glnS leuS leuS Ppro_1735 Ppro_1735 plsX plsX
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene neighborhood
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trpB-2Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (451 aa)
Ppro_1294PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: gme:Gmet_1629 homoserine dehydrogenase. (438 aa)
Ppro_1335KEGG: gsu:GSU0656 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. (357 aa)
Ppro_1336Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
Ppro_1345TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: gme:Gmet_0862 chorismate mutase, gamma, beta and epsilon. (359 aa)
Ppro_1346PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: gme:Gmet_0863 prephenate dehydrogenase:NAD-dependent glycerol-3-phosphate dehydrogenase-like. (287 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (280 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: gme:Gmet_2458 glucose-6-phosphate isomerase; Belongs to the GPI family. (529 aa)
hisSKEGG: gme:Gmet_1913 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein. (414 aa)
Ppro_1413Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. (806 aa)
Ppro_1491Iron-only hydrogenase maturation protein HydE; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_1607 biotin synthase. (357 aa)
Ppro_1493PFAM: fumarate lyase; KEGG: pca:Pcar_1630 aspartate ammonia-lyase, putative. (471 aa)
Ppro_1514KEGG: xcb:XC_0578 malonyl CoA-ACP transacylase. (319 aa)
Ppro_1515PFAM: phosphopantetheine-binding; KEGG: sat:SYN_02364 acyl carrier protein. (81 aa)
fabH-23-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (342 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: reu:Reut_A2574 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (375 aa)
Ppro_1523PFAM: phosphopantetheine-binding. (77 aa)
Ppro_1524TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_2983 benzoate-CoA ligase family. (503 aa)
Ppro_1544PFAM: Phosphoglycerate mutase; KEGG: pca:Pcar_0229 phosphoglycerate mutase family, putative. (256 aa)
Ppro_1546KEGG: gme:Gmet_1800 coenzyme F390 synthetase-like. (443 aa)
Ppro_1550Aldehyde dehydrogenase, iron-sulfur subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: pca:Pcar_0221 Fe-S oxidoreductase. (788 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (886 aa)
Ppro_1587TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: gme:Gmet_3155 glycine cleavage system T protein. (363 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (124 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
Ppro_1593PFAM: glycine cleavage system P-protein; KEGG: gme:Gmet_3152 glycine dehydrogenase subunit 2. (478 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: gme:Gmet_1277 2-dehydro-3-deoxyphosphooctonate aldolase. (272 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (429 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (506 aa)
Ppro_1669phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (433 aa)
Ppro_1681KEGG: gsu:GSU1835 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp. (470 aa)
Ppro_1687KEGG: gsu:GSU1833 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (326 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: gsu:GSU1628 phosphoglycerate kinase/triosephosphate isomerase; Belongs to the phosphoglycerate kinase family. (399 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
Ppro_1699TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: gsu:GSU1198 D-3-phosphoglycerate dehydrogenase. (539 aa)
asnSTIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: gme:Gmet_2412 asparaginyl-tRNA synthetase. (459 aa)
selDSelenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (348 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (364 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa)
Ppro_0748TIGRFAM: serine O-acetyltransferase; KEGG: gme:Gmet_0870 serine O-acetyltransferase. (230 aa)
Ppro_0776KEGG: gsu:GSU1818 phosphoglycerate mutase family protein; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein. (398 aa)
Ppro_08293-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (370 aa)
Ppro_0838PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_1394 radical SAM domain protein. (465 aa)
Ppro_0869TIGRFAM: putative L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: gme:Gmet_0487 L-threonine-O-3-phosphate decarboxylase. (358 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (777 aa)
Ppro_0905PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: pca:Pcar_2667 probable 3-oxoacyl-(acyl-carrier protein) reductase. (239 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (924 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (269 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (131 aa)
Ppro_3511KEGG: gsu:GSU0580 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (885 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (371 aa)
Ppro_3497Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: gsu:GSU1305 Glu/Leu/Phe/Val dehydrogenase family protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (469 aa)
Ppro_3483PFAM: AMP-dependent synthetase and ligase; KEGG: gme:Gmet_1469 AMP-dependent synthetase and ligase. (620 aa)
Ppro_3466TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: gsu:GSU0937 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
gluQGlutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (309 aa)
Ppro_3360TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: reu:Reut_A1327 benzoate-CoA ligase family. (505 aa)
Ppro_3359TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: gme:Gmet_0264 cysteine synthase K/M. (305 aa)
Ppro_3345PFAM: Radical SAM domain protein; KEGG: pca:Pcar_1124 Fe-S oxidoreductases-like. (338 aa)
Ppro_3342PFAM: Radical SAM domain protein; KEGG: pca:Pcar_1124 Fe-S oxidoreductases-like. (359 aa)
Ppro_3320PFAM: beta-lactamase domain protein; KEGG: gme:Gmet_3123 beta-lactamase-like. (277 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa)
Ppro_3305KEGG: gsu:GSU1193 ketose-bisphosphate aldolase family protein. (426 aa)
mqnBMethylthioadenosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (255 aa)
Ppro_3262PFAM: dihydrodipicolinate reductase; KEGG: tte:TTE0831 dihydrodipicolinate reductase; Belongs to the DapB family. (251 aa)
Ppro_3253PFAM: FAD linked oxidase domain protein; KEGG: gsu:GSU3296 glycolate oxidase subunit GlcD, putative. (459 aa)
Ppro_3236PFAM: acyl-ACP thioesterase; KEGG: gme:Gmet_1732 acyl-ACP thioesterase. (255 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (878 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (292 aa)
argDTIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: gme:Gmet_0204 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (305 aa)
argGPFAM: argininosuccinate synthase; KEGG: gsu:GSU0153 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa)
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: gsu:GSU0156 argininosuccinate lyase. (458 aa)
Ppro_3136PFAM: protein of unknown function DUF162; KEGG: dsy:DSY1922 hypothetical protein. (216 aa)
Ppro_3135PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: dsy:DSY1921 hypothetical protein. (712 aa)
Ppro_3103PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: son:SO1742 putative 3-oxoacyl-[acyl-carrier-protein] synthase III. (347 aa)
Ppro_3083PFAM: carboxyl transferase; KEGG: aba:Acid345_3025 carboxyl transferase. (516 aa)
Ppro_3082PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: aba:Acid345_3023 biotin/lipoyl attachment. (129 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (267 aa)
dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (410 aa)
glyQPFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: gme:Gmet_2942 glycyl-tRNA synthetase, alpha subunit. (292 aa)
glySglycyl-tRNA synthetase beta chain. (687 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (207 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: gsu:GSU3096 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis. (245 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
hisEPFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: gme:Gmet_0390 phosphoribosyl-ATP pyrophosphohydrolase. (108 aa)
hisG-2ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (212 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
hisC-2TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: gme:Gmet_0385 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: gme:Gmet_0386 imidazoleglycerol-phosphate dehydratase. (195 aa)
fabZ-23-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (147 aa)
lysSTIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: gme:Gmet_2360 lysyl-tRNA synthetase, class-2; Belongs to the class-II aminoacyl-tRNA synthetase family. (503 aa)
Ppro_2986PFAM: glutamine amidotransferase class-I; KEGG: gsu:GSU0936 glutamine amidotransferase, class I. (239 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (238 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (291 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (125 aa)
Ppro_2942PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_0015 radical SAM. (358 aa)
Ppro_2909PFAM: SlyX family protein; KEGG: eca:ECA4050 host factor for lysis of phiX174 infection. (67 aa)
Ppro_2894Enoyl-[acyl-carrier-protein] reductase (NADH); KEGG: gme:Gmet_2558 short-chain dehydrogenase/reductase SDR. (256 aa)
cbiACobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (463 aa)
Ppro_2887TIGRFAM: C_GCAxxG_C_C family protein; KEGG: dsy:DSY2619 hypothetical protein. (150 aa)
Ppro_2871TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: sme:SMb20652 putative asparagine synthetase protein. (678 aa)
Ppro_2867KEGG: sme:SMb20651 hypothetical protein. (98 aa)
Ppro_2845Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
Ppro_2830Sulfide dehydrogenase (flavoprotein) subunit SudA; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gsu:GSU3057 glutamate synthase (NADPH), homotetrameric. (469 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
Ppro_2815PFAM: Phosphoglycerate mutase; KEGG: gme:Gmet_0469 phosphoglycerate/bisphosphoglycerate mutase. (202 aa)
Ppro_2793PFAM: respiratory-chain NADH dehydrogenase, subunit 1; KEGG: rru:Rru_A0317 respiratory-chain NADH dehydrogenase, subunit 1. (303 aa)
Ppro_2785PFAM: respiratory-chain NADH dehydrogenase, subunit 1; KEGG: rru:Rru_A0317 respiratory-chain NADH dehydrogenase, subunit 1. (303 aa)
Ppro_2772KEGG: nmu:Nmul_A0401 hypothetical protein. (271 aa)
Ppro_2768PFAM: phosphopantetheine-binding; KEGG: nmu:Nmul_A0229 phosphopantetheine-binding. (85 aa)
Ppro_2767Serine palmitoyltransferase; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: nmu:Nmul_A0228 8-amino-7-oxononanoate synthase. (399 aa)
Ppro_2754PFAM: Radical SAM domain protein; KEGG: dvu:DVU0182 radical SAM domain protein. (332 aa)
Ppro_2736PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: gme:Gmet_0832 alcohol dehydrogenase superfamily, zinc-containing. (328 aa)
Ppro_2690PFAM: phosphoesterase, PA-phosphatase related; KEGG: pca:Pcar_0098 hypothetical protein. (166 aa)
Ppro_2669Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
Ppro_2646N-acetylglutamate synthase; PFAM: GCN5-related N-acetyltransferase; KEGG: gme:Gmet_0946 GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. (149 aa)
Ppro_2644KEGG: gme:Gmet_2566 hypothetical protein. (441 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (635 aa)
Ppro_2594Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (433 aa)
Ppro_2593KEGG: gsu:GSU0608 hypothetical protein. (416 aa)
ilvDKEGG: gsu:GSU1912 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (553 aa)
Ppro_2557TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: gsu:GSU1910 acetolactate synthase, small subunit. (163 aa)
Ppro_2556TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: gsu:GSU1910 acetolactate synthase, small subunit. (165 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
Ppro_25503-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa)
Ppro_2540PFAM: FAD linked oxidase domain protein; KEGG: dsy:DSY3357 hypothetical protein. (464 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: gme:Gmet_1769 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (310 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: gsu:GSU1273 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (373 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: gme:Gmet_1774 carbamoyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. (1078 aa)
Ppro_2520PFAM: beta-lactamase domain protein; KEGG: afu:AF1343 hypothetical protein. (306 aa)
Ppro_2507PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_1394 radical SAM domain protein. (421 aa)
Ppro_2495TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: gme:Gmet_1300 cysteine desulphurase related, unknown function. (385 aa)
Ppro_2466TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: dar:Daro_2408 asparagine synthase, glutamine-hydrolyzing. (625 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: gme:Gmet_2492 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (209 aa)
Ppro_2395KEGG: gsu:GSU1695 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (461 aa)
Ppro_2361PFAM: shikimate kinase; KEGG: pca:Pcar_2174 shikimate kinase II. (175 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa)
Ppro_2350PFAM: Chorismate mutase; KEGG: dar:Daro_4076 chorismate mutase. (107 aa)
Ppro_2334PFAM: protein of unknown function DUF479; KEGG: gme:Gmet_2389 protein of unknown function DUF479. (203 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (594 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa)
Ppro_2313TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: gsu:GSU1798 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (522 aa)
thrSSer-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (636 aa)
pheSKEGG: gme:Gmet_1415 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc; aminoacyl tRNA synthetase, class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa)
pheTKEGG: gme:Gmet_1416 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (814 aa)
Ppro_2262KEGG: gme:Gmet_1880 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (404 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (127 aa)
Ppro_2253KEGG: sat:SYN_02778 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS. (400 aa)
Ppro_2249TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: gme:Gmet_2620 6-phosphogluconate dehydrogenase related protein. (341 aa)
lipA-2Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (280 aa)
Ppro_21672,3-dimethylmalate lyase; TIGRFAM: phosphoenolpyruvate phosphomutase; KEGG: pca:Pcar_0628 phosphoenolpyruvate phosphomutase. (297 aa)
Ppro_2166PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pca:Pcar_0629 D-3-phosphoglycerate dehydrogenase. (357 aa)
Ppro_2161Glutamate synthase (NADPH) GltB1 subunit; KEGG: pca:Pcar_2598 hypothetical protein. (368 aa)
Ppro_2160Ferredoxin-dependent glutamate synthase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ferredoxin-dependent glutamate synthase; KEGG: pca:Pcar_2599 glutamate synthase, alpha subunit-like; Belongs to the glutamate synthase family. (547 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (391 aa)
bioCMethyltransferase type 11; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (278 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (393 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (359 aa)
Ppro_2023Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
Ppro_2022acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
gcvH-2Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (520 aa)
Ppro_1995PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: gme:Gmet_0219 Orn/DAP/Arg decarboxylase 2. (439 aa)
Ppro_1952PFAM: beta-lactamase domain protein; KEGG: pca:Pcar_1589 hypothetical protein. (304 aa)
Ppro_1949KEGG: pca:Pcar_0171 hypothetical protein. (117 aa)
Ppro_1945PFAM: beta-lactamase domain protein; KEGG: gme:Gmet_3123 beta-lactamase-like. (278 aa)
Ppro_1743[Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: gsu:GSU1602 malonyl CoA-acyl carrier protein transacylase. (306 aa)
Ppro_19273-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: gsu:GSU1902 3-isopropylmalate dehydratase, small subunit, putative. (175 aa)
Ppro_1926KEGG: gsu:GSU1903 3-isopropylmalate dehydratase, large subunit, putative; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein. (427 aa)
Ppro_1853Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (356 aa)
Ppro_1852PFAM: pyruvate kinase; KEGG: sat:SYN_02952 pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
Ppro_1832TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sat:SYN_01253 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa)
Ppro_1831Cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gme:Gmet_0699 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. (381 aa)
Ppro_1830Cysteine synthase / cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: gme:Gmet_0698 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. (383 aa)
Ppro_1787KEGG: gme:Gmet_2390 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase. (428 aa)
Ppro_1765TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: gsu:GSU1754 L-lysine 2,3-aminomutase. (346 aa)
Ppro_1764PFAM: tRNA synthetase, class II (D, K and N); KEGG: gsu:GSU1753 lysyl-tRNA synthetase-related protein. (301 aa)
Ppro_1754phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (435 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (576 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (348 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
Ppro_17463-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
Ppro_17443-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
Ppro_0907PFAM: beta-ketoacyl synthase; KEGG: dps:DP1859 related to 3-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
acpPPhosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (88 aa)
Ppro_0910KEGG: dps:DP1856 similar to coenzyme F390 synthetase. (436 aa)
Ppro_0911PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pca:Pcar_2660 coenzyme PQQ synthesis protein-like. (497 aa)
Ppro_0915KEGG: pca:Pcar_2655 hypothetical protein. (132 aa)
Ppro_0917PFAM: beta-ketoacyl synthase; KEGG: dps:DP1840 related to 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (380 aa)
Ppro_0918KEGG: dps:DP1854 hypothetical protein. (224 aa)
Ppro_0923KEGG: pca:Pcar_2651 acyl-carrier protein-like. (94 aa)
Ppro_0926PFAM: beta-ketoacyl synthase; KEGG: pca:Pcar_2650 related to 3-oxoacyl-acyl carrier protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (392 aa)
Ppro_0927PFAM: beta-ketoacyl synthase; KEGG: pca:Pcar_2649 3-oxoacyl-(acyl-carrier-protein) synthase-like; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (357 aa)
Ppro_0928PFAM: phosphopantetheine-binding. (80 aa)
Ppro_0931PFAM: Pyridoxal-dependent decarboxylase; KEGG: gme:Gmet_1644 pyridoxal-dependent decarboxylase. (567 aa)
argSKEGG: gme:Gmet_1434 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (563 aa)
Ppro_1022PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: gsu:GSU1816 UDP-glucose 6-dehydrogenase. (452 aa)
Ppro_1024Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: pca:Pcar_0343 acetoin dehydrogenase complex, E1 component, alpha subunit. (324 aa)
Ppro_1025PFAM: Transketolase, central region; Transketolase domain protein; KEGG: reu:Reut_B5551 transketolase, central region:transketolase, C-terminal. (333 aa)
Ppro_1026PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; KEGG: pca:Pcar_0345 dehydrogenase complex E2 component, dihydrolipamide acetyltransferase. (450 aa)
Ppro_1027Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: pca:Pcar_0343 acetoin dehydrogenase complex, E1 component, alpha subunit. (324 aa)
Ppro_1028PFAM: Transketolase, central region; Transketolase domain protein; KEGG: reu:Reut_B5551 transketolase, central region:transketolase, C-terminal. (333 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (314 aa)
Ppro_1041methylmalonyl-CoA epimerase; KEGG: pca:Pcar_0333 hypothetical protein. (164 aa)
Ppro_1043PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pca:Pcar_0330 2,3-butanediol dehydrogenase. (353 aa)
Ppro_1061PFAM: thioesterase superfamily protein; KEGG: pca:Pcar_1366 acyl-CoA hydrolase-like. (351 aa)
Ppro_1079TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: mbu:Mbur_0274 protein of unknown function DUF160. (440 aa)
Ppro_1080PFAM: GCN5-related N-acetyltransferase; KEGG: pca:Pcar_1402 L-lysine 2,3-aminomutase, putative/acetyltransferase, GNAT family. (296 aa)
Ppro_1087Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase. (87 aa)
Ppro_1089KEGG: dvu:DVU0997 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (290 aa)
Ppro_1144PFAM: beta-lactamase domain protein; KEGG: gsu:GSU1631 metallo-beta-lactamase family protein. (256 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa)
Ppro_1160TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. (425 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (328 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (243 aa)
bioAAminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (425 aa)
Ppro_1187Phosphoglycolate phosphatase; KEGG: gme:Gmet_2290 HAD-superfamily hydrolase subfamily IA; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. (218 aa)
Ppro_1192PFAM: Radical SAM domain protein; KEGG: gsu:GSU0685 radical SAM domain protein. (332 aa)
Ppro_1210Ethanolamine ammonia-lyase light chain; PFAM: Ethanolamine ammonia lyase large subunit; KEGG: pca:Pcar_0491 ethanolamine ammonia-lyase large subunit-like. (760 aa)
Ppro_1277TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: tdn:Tmden_0272 CoA enzyme activase. (259 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (327 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; KEGG: gme:Gmet_0057 cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
Ppro_0034PFAM: carboxyl transferase; KEGG: aba:Acid345_3025 carboxyl transferase. (516 aa)
Ppro_0035PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: aba:Acid345_3023 biotin/lipoyl attachment. (129 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa)
Ppro_0046KEGG: gme:Gmet_0603 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (365 aa)
Ppro_0047KEGG: gme:Gmet_0604 aspartate-semialdehyde dehydrogenase, USG-1 related; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
Ppro_0050PFAM: asparagine synthase; KEGG: mlo:mll5256 similar to asparagine synthetase. (636 aa)
Ppro_0088Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
Ppro_0132Hypothetical protein; KEGG: ape:APE0026 phosphoenolpyruvate synthase. (76 aa)
Ppro_0283PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. (615 aa)
Ppro_0286PFAM: acetyl-CoA hydrolase/transferase; KEGG: gme:Gmet_3044 acetyl-CoA hydrolase/transferase. (531 aa)
Ppro_0296KEGG: gme:Gmet_0495 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (162 aa)
Ppro_0302Methylthioadenosine nucleosidase; PFAM: purine and other phosphorylases, family 1; KEGG: gsu:GSU1897 MTA/SAH nucleosidase, putative. (241 aa)
Ppro_0319PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: dps:DP1201 related to pyruvate synthase, subunit PorB. (259 aa)
Ppro_0321KEGG: sat:SYN_02383 phosphoenolpyruvate synthase. (892 aa)
Ppro_0322TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: ctc:CTC02528 pyruvate synthase subunit porC. (191 aa)
Ppro_0323TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: tma:TM0016 pyruvate ferredoxin oxidoreductase, delta subunit. (96 aa)
Ppro_0324Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ctc:CTC02526 pyruvate synthase subunit porA. (396 aa)
Ppro_0325Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: ctc:CTC02525 pyruvate synthase subunit porB. (311 aa)
Ppro_0337KEGG: gsu:GSU0740 NAD-dependent dehydrogenase subunit. (302 aa)
Ppro_0338KEGG: gme:Gmet_2599 NAD-dependent dehydrogenase subunit. (213 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (147 aa)
Ppro_0364KEGG: sdn:Sden_2998 hypothetical protein. (821 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (287 aa)
Ppro_0452TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_1038 isocitrate dehydrogenase. (470 aa)
Ppro_0469PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase, beta subunit. (301 aa)
Ppro_0470PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mta:Moth_1922 pyruvate flavodoxin/ferredoxin oxidoreductase-like. (418 aa)
Ppro_0471TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE3276 2-ketoacid ferredoxin oxidoreductase delta subunit. (105 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (518 aa)
folDMethenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (346 aa)
hisZhistidyl-tRNA synthetase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (445 aa)
Ppro_0550Fumarase; PFAM: fumarate lyase; KEGG: gme:Gmet_3082 fumarate lyase. (467 aa)
Ppro_0566Acetylornithine aminotransferase apoenzyme; PFAM: aminotransferase class-III; KEGG: sat:SYN_01215 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
Ppro_0567KEGG: gsu:GSU2486 hypothetical protein. (441 aa)
Ppro_0579KEGG: fra:Francci3_1867 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (355 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa)
Ppro_0623Aconitate hydratase domain protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (175 aa)
leuCHomoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (427 aa)
Ppro_0642KEGG: chy:CHY_0443 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (912 aa)
Ppro_0643Nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: gme:Gmet_3222 nitrite and sulphite reductase 4Fe-4S region. (219 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: gme:Gmet_2494 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (267 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (350 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (393 aa)
Ppro_0729PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; KEGG: gme:Gmet_0147 ferredoxin-dependent glutamate synthase. (1507 aa)
Ppro_0734D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: bca:BCE3284 D-3-phosphoglycerate dehydrogenase, putative. (390 aa)
Ppro_1713PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: aba:Acid345_4115 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa)
glnSKEGG: gsu:GSU3366 glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase, class Ic. (565 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: gme:Gmet_2300 leucyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (823 aa)
Ppro_1735PFAM: Chorismate mutase; KEGG: gme:Gmet_1955 chorismate mutase. (94 aa)
plsXPhosphate:acyl-[acyl carrier protein] acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (346 aa)
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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