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cysS cysS Ppro_0050 Ppro_0050 Ppro_0063 Ppro_0063 Ppro_0436 Ppro_0436 Ppro_0579 Ppro_0579 argS argS Ppro_1049 Ppro_1049 Ppro_1071 Ppro_1071 Ppro_1088 Ppro_1088 queC queC Ppro_1563 Ppro_1563 valS valS metG metG Ppro_1687 Ppro_1687 glnS glnS leuS leuS mnmA mnmA guaA guaA Ppro_2012 Ppro_2012 nadE nadE Ppro_2466 Ppro_2466 nadD nadD ileS ileS hldE hldE panC panC ttcA ttcA gltX gltX gluQ gluQ tyrS tyrS argG argG Ppro_3112 Ppro_3112 Ppro_2871 Ppro_2871 nadE-2 nadE-2 Ppro_2517 Ppro_2517 coaD coaD tilS tilS Ppro_2396 Ppro_2396
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cysSTIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; KEGG: gme:Gmet_0057 cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
Ppro_0050PFAM: asparagine synthase; KEGG: mlo:mll5256 similar to asparagine synthetase. (636 aa)
Ppro_0063TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: bur:Bcep18194_A5495 sulfate adenylyltransferase, small subunit. (301 aa)
Ppro_0436PFAM: UspA domain protein; KEGG: gme:Gmet_2678 UspA. (151 aa)
Ppro_0579KEGG: fra:Francci3_1867 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (355 aa)
argSKEGG: gme:Gmet_1434 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (563 aa)
Ppro_1049KEGG: chy:CHY_1281 conserved hypothetical protein TIGR00268. (275 aa)
Ppro_1071PFAM: thiamine biosynthesis protein; KEGG: gsu:GSU0434 hypothetical protein. (335 aa)
Ppro_1088Citrate lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (338 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa)
Ppro_1563PFAM: UspA domain protein; KEGG: sat:SYN_02484 universal stress protein family. (266 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (886 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (506 aa)
Ppro_1687KEGG: gsu:GSU1833 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib. (326 aa)
glnSKEGG: gsu:GSU3366 glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase, class Ic. (565 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: gme:Gmet_2300 leucyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (823 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (355 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (520 aa)
Ppro_2012Deoxyribodipyrimidine photo-lyase type II; KEGG: gsu:GSU2829 deoxyribodipyrimidine photolyase, putative; TIGRFAM: deoxyribodipyrimidine photolyase; PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein. (450 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (689 aa)
Ppro_2466TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: dar:Daro_2408 asparagine synthase, glutamine-hydrolyzing. (625 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (221 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (924 aa)
hldED-alpha,beta-D-heptose 7-phosphate 1-kinase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (488 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (269 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (469 aa)
gluQGlutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (309 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa)
argGPFAM: argininosuccinate synthase; KEGG: gsu:GSU0153 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa)
Ppro_3112PFAM: UspA domain protein; KEGG: mac:MA3944 universal stress protein. (290 aa)
Ppro_2871TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: sme:SMb20652 putative asparagine synthetase protein. (678 aa)
nadE-2NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (332 aa)
Ppro_2517FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: gme:Gmet_1388 riboflavin kinase / FAD synthetase; Belongs to the ribF family. (325 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (485 aa)
Ppro_2396PFAM: protein of unknown function DUF218; KEGG: gsu:GSU2233 hypothetical protein. (198 aa)
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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