94 items (Streptomyces avermitilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KUN57354.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (107 aa)
	KUN56353.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
	PrpM3	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (933 aa)
	KUN56395.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
	PrpE2	Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (711 aa)
	KUN56519.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	KUN56606.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
	KUN56657.1	Regulator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	arsI	Metal ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (122 aa)
	Sig29	RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (310 aa)
	KUN57161.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
	AQJ43_04970	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	KUN56970.1	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
	KUN56975.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (126 aa)
	KUN57049.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (107 aa)
	PrpJ6	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
	KUN57066.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
	KUN57072.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
	KUN55978.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
	KUN55820.1	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
	KUN55141.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
	PrpJ5	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)
	PrpB6	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	PrpC5	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
	KUN55327.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
	PrpB5	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	KUN54780.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
	KUN54781.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
	KUN54782.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
	KUN54783.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
	PrpB4	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
	PrpI2	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
	RsbT	Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
	RsbS	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
	RsbR	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
	PrpB3	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	KUN54790.1	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
	KUN54791.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (129 aa)
	Sig14	RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (295 aa)
	PrpJ4	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
	KUN54455.1	Isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
	PrpG2	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
	KUN54662.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	KUN53504.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
	PrpB12	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
	PrpM5	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
	PrpL3	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
	PrpM4	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (690 aa)
	KUN53383.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
	PrpJ7	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)
	PrsR	Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
	KUN53076.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	PrpB9	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
	KUN52817.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
	PrpE3	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
	PrpC6	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (922 aa)
	KUN52481.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
	KUN52482.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
	KUN52484.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
	KUN52485.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (125 aa)
	KUN52378.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
	HemN	Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (413 aa)
	PrpK	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
	KUN52316.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1357 aa)
	PrpB11	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
	KUN52087.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
	KUN51893.1	Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
	KUN51816.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
	KUN51734.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
	KUN51650.1	Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
	KUN51496.1	Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (988 aa)
	PrpJ2	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
	PrpJ3	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (909 aa)
	PrpC2	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
	PrpC4	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (785 aa)
	PrpB1	Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
	PrpD	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (707 aa)
	PrpM1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (808 aa)
	rsbV_4	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (122 aa)
	PrpL1	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (820 aa)
	PrpJ1	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (770 aa)
	PrpC1	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
	OsaC	PAS domain S-box protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)
	OsaA	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1797 aa)
	KUN50198.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
	PrpG1	Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
	PrpC7	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (847 aa)
	PrpJ8	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
	PrpL4	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (797 aa)
	KUN50111.1	Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
	Sig57	RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (264 aa)
	KUN49105.1	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
	KUN47276.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
	PrpB2	Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)

Your Current Organism:

Streptomyces avermitilis

NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQJ43_04970	KUN49105.1	AQJ43_04970	AQJ43_35995	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AQJ43_04970	KUN50198.1	AQJ43_04970	AQJ43_33595	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.795
AQJ43_04970	KUN51496.1	AQJ43_04970	AQJ43_27740	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
AQJ43_04970	KUN51650.1	AQJ43_04970	AQJ43_27155	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424
AQJ43_04970	KUN51734.1	AQJ43_04970	AQJ43_26245	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.448
AQJ43_04970	KUN51893.1	AQJ43_04970	AQJ43_25480	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.795
AQJ43_04970	KUN52087.1	AQJ43_04970	AQJ43_24290	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AQJ43_04970	KUN52316.1	AQJ43_04970	AQJ43_23495	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.589
AQJ43_04970	KUN52481.1	AQJ43_04970	AQJ43_21940	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AQJ43_04970	KUN52817.1	AQJ43_04970	AQJ43_20100	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.795
AQJ43_04970	KUN53504.1	AQJ43_04970	AQJ43_15350	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.503
AQJ43_04970	KUN54662.1	AQJ43_04970	AQJ43_15270	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424
AQJ43_04970	KUN54783.1	AQJ43_04970	AQJ43_11015	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424
AQJ43_04970	KUN55820.1	AQJ43_04970	AQJ43_06985	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AQJ43_04970	KUN55978.1	AQJ43_04970	AQJ43_06100	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.403
AQJ43_04970	KUN56606.1	AQJ43_04970	AQJ43_03150	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.802
AQJ43_04970	KUN56657.1	AQJ43_04970	AQJ43_03460	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Regulator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424
AQJ43_04970	KUN57066.1	AQJ43_04970	AQJ43_05775	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
AQJ43_04970	KUN57072.1	AQJ43_04970	AQJ43_05805	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424
AQJ43_04970	KUN57161.1	AQJ43_04970	AQJ43_04860	Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.424

page 1 of 233

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Textmining

Cooccurrence

Databases

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About