(19 nodes) Phenol-containing compound metabolic process network (Streptomyces avermitilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FahA	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
	KUN55936.1	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
	KUN52819.1	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	PptA2	4'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	PcaB	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
	PcaH	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	KUN55171.1	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	KUN52967.1	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
	KUN50588.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)
	MelC1-2	Tyrosinase co-factor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
	HpcE	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	KUN51406.1	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
	KUN50692.1	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
	KUN53384.1	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	melC2	Tyrosinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
	melC1	Tyrosinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
	KUN54727.1	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
	KUN54659.1	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
	SsgC	Sporulation protein SsgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)

Your Current Organism:

Streptomyces avermitilis

NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FahA	KUN55936.1	AQJ43_22310	AQJ43_07635	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.485
HpcE	KUN53384.1	AQJ43_25520	AQJ43_18315	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
HpcE	KUN55171.1	AQJ43_25520	AQJ43_09520	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.598
KUN50588.1	PptA2	AQJ43_32670	AQJ43_07780	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	4'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.764
KUN52819.1	PcaB	AQJ43_20110	AQJ43_07990	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
KUN52819.1	PcaH	AQJ43_20110	AQJ43_08000	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.469
KUN52967.1	PcaB	AQJ43_20935	AQJ43_07990	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
KUN52967.1	PcaH	AQJ43_20935	AQJ43_08000	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.474
KUN53384.1	HpcE	AQJ43_18315	AQJ43_25520	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
KUN53384.1	KUN55171.1	AQJ43_18315	AQJ43_09520	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
KUN54659.1	PcaB	AQJ43_15255	AQJ43_07990	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
KUN54659.1	PcaH	AQJ43_15255	AQJ43_08000	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
KUN54727.1	PcaB	AQJ43_15240	AQJ43_07990	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.464
KUN54727.1	PcaH	AQJ43_15240	AQJ43_08000	Protocatechuate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
KUN55171.1	HpcE	AQJ43_09520	AQJ43_25520	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.598
KUN55171.1	KUN53384.1	AQJ43_09520	AQJ43_18315	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
KUN55936.1	FahA	AQJ43_07635	AQJ43_22310	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.485
KUN55936.1	PcaB	AQJ43_07635	AQJ43_07990	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.631
KUN55936.1	PcaH	AQJ43_07635	AQJ43_08000	4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Protocatechuate 3,4-dioxygenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.781
MelC1-2	melC2	AQJ43_24535	AQJ43_10835	Tyrosinase co-factor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tyrosinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.719

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