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nuoN_2 nuoN_2 NuoM2 NuoM2 NuoL2 NuoL2 nuoK1 nuoK1 nuoN_1 nuoN_1 NuoM1 NuoM1 nuoL nuoL ctaD1_1 ctaD1_1 ctaC ctaC FdnI FdnI ctaD1_2 ctaD1_2 HydB HydB CydA1 CydA1 CydB1 CydB1 NuoG1 NuoG1 CydB2 CydB2 CydA2 CydA2 KUN55498.1 KUN55498.1 GlcD1 GlcD1 qcrB qcrB nuoK2 nuoK2 ctaE ctaE GlcD2 GlcD2 KUN50997.1 KUN50997.1 MrpD MrpD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nuoN_2NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (499 aa)
NuoM2NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
NuoL2NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
nuoK1NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (129 aa)
nuoN_1NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (549 aa)
NuoM1NADH:ubiquinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
nuoLNADH:ubiquinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
ctaD1_1Cytochrome ubiquinol oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (579 aa)
ctaCCytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
FdnIFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
ctaD1_2Cytochrome ubiquinol oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (563 aa)
HydBHydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
CydA1Cytochrome BD ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
CydB1Cytochrome C oxidase assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
NuoG1NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (834 aa)
CydB2Cytochrome BD oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
CydA2Cytochrome BD ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
KUN55498.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
GlcD1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
qcrBUbiquinol-cytochrome c reductase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
nuoK2NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (99 aa)
ctaEDerived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
GlcD2FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
KUN50997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (59 aa)
MrpDNADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680
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