(22 nodes) Aminotransferase, class I/classII network (Streptomyces avermitilis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	AspB2	Succinyldiaminopimelate transaminase; Catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
	KUN56372.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
	AspB3	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
	KUN56609.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
	AspB1	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
	KUN55850.1	Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
	kbl	2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)
	KUN54886.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
	CobC	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
	KUN54217.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
	hisC	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
	KUN54655.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
	KUN53498.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
	KUN53538.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
	KUN53703.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
	BioF	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	KUN53247.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
	KUN53209.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
	pat	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
	KUN52970.1	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
	AspC1	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
	DapC	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)

Your Current Organism:

Streptomyces avermitilis

NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AspB1	AspB3	AQJ43_06440	AQJ43_02440	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AspB1	AspC1	AQJ43_06440	AQJ43_22570	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AspB2	hisC	AQJ43_01650	AQJ43_13270	Succinyldiaminopimelate transaminase; Catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.411
AspB3	AspB1	AQJ43_02440	AQJ43_06440	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AspB3	AspC1	AQJ43_02440	AQJ43_22570	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AspC1	AspB1	AQJ43_22570	AQJ43_06440	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AspC1	AspB3	AQJ43_22570	AQJ43_02440	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AspC1	CobC	AQJ43_22570	AQJ43_12025	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
AspC1	hisC	AQJ43_22570	AQJ43_13270	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.820
AspC1	pat	AQJ43_22570	AQJ43_20795	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.842
CobC	AspC1	AQJ43_12025	AQJ43_22570	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
CobC	hisC	AQJ43_12025	AQJ43_13270	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.914
CobC	pat	AQJ43_12025	AQJ43_20795	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.908
hisC	AspB2	AQJ43_13270	AQJ43_01650	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Succinyldiaminopimelate transaminase; Catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.411
hisC	AspC1	AQJ43_13270	AQJ43_22570	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
hisC	CobC	AQJ43_13270	AQJ43_12025	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
hisC	pat	AQJ43_13270	AQJ43_20795	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.915
pat	AspC1	AQJ43_20795	AQJ43_22570	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.842
pat	CobC	AQJ43_20795	AQJ43_12025	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
pat	hisC	AQJ43_20795	AQJ43_13270	Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.915

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