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anmK anmK GuxA2 GuxA2 CelA2 CelA2 XynA1 XynA1 NagA NagA murQ murQ GalE1 GalE1 galK galK GlgB GlgB nagB nagB GlpX GlpX xylA xylA CelA5 CelA5 GalM1 GalM1 GalM2 GalM2 AmyA4 AmyA4 zwf_2-2 zwf_2-2 KUN54106.1 KUN54106.1 aguA_2 aguA_2 zwf_2 zwf_2 glgE1_2 glgE1_2 CelA4 CelA4 KUN50041.1 KUN50041.1 glgB1 glgB1 GuxA1 GuxA1 CelA1 CelA1 rbsK rbsK rbsD rbsD CslZ CslZ MalQ MalQ XynA2 XynA2 xylB xylB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (384 aa)
GuxA2Cellulose 1,4-beta-cellobiosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase family 6. (569 aa)
CelA2Cellulose-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
XynA11,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
NagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (311 aa)
GalE1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (319 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (380 aa)
GlgBHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (727 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (261 aa)
GlpXFructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
xylAXylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family. (388 aa)
CelA5Endoglucanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase family 6. (370 aa)
GalM1Aldose epimerase; Converts alpha-aldose to the beta-anomer. (383 aa)
GalM2Aldose epimerase; Converts alpha-aldose to the beta-anomer. (326 aa)
AmyA4Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
zwf_2-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
KUN54106.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
aguA_2Alpha-glucuronidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 67 family. (680 aa)
zwf_2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (548 aa)
glgE1_2Hypothetical protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (78 aa)
CelA4Endo-1,4-beta-glucanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 12 (cellulase H) family. (269 aa)
KUN50041.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 12 (cellulase H) family. (237 aa)
glgB1Hypothetical protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (725 aa)
GuxA1Cellobiohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase family 6. (741 aa)
CelA1Glycosyl hydrolase family 5; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 12 (cellulase H) family. (375 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
rbsDRibose ABC transporter; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (129 aa)
CslZEndoglucanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase family 6. (338 aa)
MalQ4-alpha-glucanotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
XynA2Endo-1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
xylBXylulose kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680
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