STRINGSTRING
mqnB mqnB mqnD mqnD KUN55936.1 KUN55936.1 UbiX UbiX ubiA ubiA ubiX ubiX mqnE mqnE MqnA MqnA MqnC MqnC menG menG KUN52564.1 KUN52564.1 hpd hpd WrbA WrbA Add2 Add2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mqnBFutalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (223 aa)
mqnD1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (284 aa)
KUN55936.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
UbiXMenaquinone biosynthesis decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. (483 aa)
ubiA4-hydroxybenzoate octaprenyltransferase; UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (215 aa)
mqnEAminofutalosine synthase MqnE; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (387 aa)
MqnAMenaquinone biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
MqnCDehypoxanthine futalosine cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
menGUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (231 aa)
KUN52564.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
hpd4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
WrbANADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
Add2Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 33903
Other names: ATCC 31267, DSM 46492, JCM 5070, NBRC 14893, NCIMB 12804, NRRL 8165, S. avermitilis, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, strain MA-4680
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