(12 nodes) Mixed, incl. Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, and Lipase activity network (Lysinibacillus macroides)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KOY83787.1	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family. (158 aa)
	msrA	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (156 aa)
	KOY83523.1	Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
	KOY83524.1	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
	KOY83712.1	Lysophospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	KOY83525.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
	msrA-2	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)
	msrB	Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
	msrA-3	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (172 aa)
	KOY82189.1	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
	KOY81896.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
	msrA-4	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (156 aa)

Your Current Organism:

Lysinibacillus macroides

NCBI taxonomy Id: 33935
Other names: ATCC 12905, Bacillus macroides, DSM 54, L. macroides, LMG 18474, LMG:18474, Lineola longa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KOY81896.1	KOY83787.1	ADM90_13390	ADM90_02495	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.	0.528
KOY81896.1	msrA	ADM90_13390	ADM90_07625	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.765
KOY81896.1	msrA-2	ADM90_13390	ADM90_09790	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.765
KOY81896.1	msrA-3	ADM90_13390	ADM90_10185	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.765
KOY81896.1	msrA-4	ADM90_13390	ADM90_20650	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.765
KOY81896.1	msrB	ADM90_13390	ADM90_09795	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.696
KOY82189.1	KOY83787.1	ADM90_11150	ADM90_02495	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.	0.770
KOY82189.1	msrA	ADM90_11150	ADM90_07625	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.708
KOY82189.1	msrA-2	ADM90_11150	ADM90_09790	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.708
KOY82189.1	msrA-3	ADM90_11150	ADM90_10185	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.708
KOY82189.1	msrA-4	ADM90_11150	ADM90_20650	Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.708
KOY83523.1	KOY83524.1	ADM90_09770	ADM90_09775	Derived by automated computational analysis using gene prediction method: Protein Homology.	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.565
KOY83523.1	msrB	ADM90_09770	ADM90_09795	Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.443
KOY83524.1	KOY83523.1	ADM90_09775	ADM90_09770	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.565
KOY83524.1	KOY83525.1	ADM90_09775	ADM90_09785	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.463
KOY83524.1	KOY83712.1	ADM90_09775	ADM90_09780	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lysophospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.459
KOY83524.1	msrB	ADM90_09775	ADM90_09795	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
KOY83525.1	KOY83524.1	ADM90_09785	ADM90_09775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DegV domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.463
KOY83525.1	KOY83712.1	ADM90_09785	ADM90_09780	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lysophospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
KOY83525.1	msrA-2	ADM90_09785	ADM90_09790	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.758