STRINGSTRING
HCAG_00552 HCAG_00552 HCAG_00812 HCAG_00812 NBP35 NBP35 HCAG_01026 HCAG_01026 HCAG_01147 HCAG_01147 HCAG_01208 HCAG_01208 HCAG_01217 HCAG_01217 HCAG_01232 HCAG_01232 HCAG_01495 HCAG_01495 HCAG_01676 HCAG_01676 HCAG_01677 HCAG_01677 HCAG_01989 HCAG_01989 CIA1 CIA1 DRE2 DRE2 HCAG_02212 HCAG_02212 HCAG_02578 HCAG_02578 HCAG_02734 HCAG_02734 HCAG_02735 HCAG_02735 HCAG_02818 HCAG_02818 HCAG_02819 HCAG_02819 HCAG_02930 HCAG_02930 HCAG_03616 HCAG_03616 HCAG_03887 HCAG_03887 HCAG_05279 HCAG_05279 HCAG_06460 HCAG_06460 HCAG_05962 HCAG_05962 HCAG_06107 HCAG_06107 HCAG_07078 HCAG_07078 HCAG_08081 HCAG_08081 TPC1 TPC1 HCAG_08291 HCAG_08291 HCAG_09185 HCAG_09185
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCAG_00552Uncharacterized protein. (328 aa)
HCAG_00812FeS_assembly_P domain-containing protein. (235 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
HCAG_01026Uncharacterized protein. (867 aa)
HCAG_01147Cysteine desulfurase, mitochondrial. (986 aa)
HCAG_01208Uncharacterized protein. (601 aa)
HCAG_01217Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (465 aa)
HCAG_01232Putative_PNPOx domain-containing protein. (246 aa)
HCAG_01495Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (630 aa)
HCAG_01676Uncharacterized protein. (393 aa)
HCAG_01677Iron-binding protein iscA. (285 aa)
HCAG_01989Yae1_N domain-containing protein. (490 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (491 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (351 aa)
HCAG_02212BPL/LPL catalytic domain-containing protein. (394 aa)
HCAG_02578Uncharacterized protein. (162 aa)
HCAG_02734Uncharacterized protein. (361 aa)
HCAG_02735J domain-containing protein. (279 aa)
HCAG_02818Uncharacterized protein. (652 aa)
HCAG_02819MMS19_C domain-containing protein. (174 aa)
HCAG_02930FAD-binding FR-type domain-containing protein. (422 aa)
HCAG_03616Nfu_N domain-containing protein. (279 aa)
HCAG_03887Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (156 aa)
HCAG_05279Uncharacterized protein; Belongs to the BolA/IbaG family. (94 aa)
HCAG_06460Yae1_N domain-containing protein. (313 aa)
HCAG_05962Aminotran_5 domain-containing protein. (422 aa)
HCAG_06107Uncharacterized protein. (228 aa)
HCAG_07078Uncharacterized protein. (302 aa)
HCAG_08081Fe-S_biosyn domain-containing protein. (230 aa)
TPC1Mitochondrial thiamine pyrophosphate carrier 1; Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa)
HCAG_08291Uncharacterized protein. (278 aa)
HCAG_09185Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (203 aa)
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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