(27 nodes) Steroid biosynthesis, and C-4 methylsterol oxidase activity network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00205	Uncharacterized protein. (135 aa)
	HCAG_00257	3Beta_HSD domain-containing protein. (426 aa)
	HCAG_00613	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (626 aa)
	HCAG_01150	Uncharacterized protein. (183 aa)
	HCAG_01378	Delta(24(24(1)))-sterol reductase. (539 aa)
	HCAG_01553	Uncharacterized protein. (449 aa)
	HCAG_01705	C-2428 sterol reductase. (475 aa)
	HCAG_01791	Uncharacterized protein. (172 aa)
	HCAG_02739	Uncharacterized protein. (417 aa)
	HCAG_02957	SE domain-containing protein. (484 aa)
	HCAG_03184	Uncharacterized protein; Belongs to the cytochrome P450 family. (471 aa)
	HCAG_04048	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family. (525 aa)
	HCAG_04481	Cytochrome P450 51; Belongs to the cytochrome P450 family. (522 aa)
	HCAG_04797	Epimerase domain-containing protein. (364 aa)
	HCAG_04885	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (239 aa)
	HCAG_05272	3Beta_HSD domain-containing protein. (456 aa)
	HCAG_05359	Uncharacterized protein. (170 aa)
	HCAG_06436	FAD-binding PCMH-type domain-containing protein. (685 aa)
	HCAG_06888	C-5 sterol desaturase; Belongs to the sterol desaturase family. (272 aa)
	HCAG_06936	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (740 aa)
	HCAG_06937	Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
	HCAG_06013	Cytochrome P450 61; Belongs to the cytochrome P450 family. (554 aa)
	HCAG_07071	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (253 aa)
	HCAG_07128	Uncharacterized protein. (110 aa)
	HCAG_07564	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (380 aa)
	HCAG_07650	C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (230 aa)
	HCAG_07922	Squalene synthetase. (493 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00205	HCAG_00257	A6QS49	A6QSA1	Uncharacterized protein.	3Beta_HSD domain-containing protein.	0.753
HCAG_00205	HCAG_00613	A6QS49	A6QTA7	Uncharacterized protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.458
HCAG_00205	HCAG_01150	A6QS49	A6QUU4	Uncharacterized protein.	Uncharacterized protein.	0.891
HCAG_00205	HCAG_01378	A6QS49	A6QVH1	Uncharacterized protein.	Delta(24(24(1)))-sterol reductase.	0.754
HCAG_00205	HCAG_01553	A6QS49	A6QVZ6	Uncharacterized protein.	Uncharacterized protein.	0.888
HCAG_00205	HCAG_01705	A6QS49	A6QWE8	Uncharacterized protein.	C-2428 sterol reductase.	0.754
HCAG_00205	HCAG_01791	A6QS49	A6QWN4	Uncharacterized protein.	Uncharacterized protein.	0.558
HCAG_00205	HCAG_02957	A6QS49	A6R000	Uncharacterized protein.	SE domain-containing protein.	0.905
HCAG_00205	HCAG_03184	A6QS49	A6R0M7	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.425
HCAG_00205	HCAG_04048	A6QS49	A6R340	Uncharacterized protein.	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family.	0.840
HCAG_00205	HCAG_04481	A6QS49	A6R4C3	Uncharacterized protein.	Cytochrome P450 51; Belongs to the cytochrome P450 family.	0.840
HCAG_00205	HCAG_04885	A6QS49	A6R5H7	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.497
HCAG_00205	HCAG_05272	A6QS49	A6R6L4	Uncharacterized protein.	3Beta_HSD domain-containing protein.	0.753
HCAG_00205	HCAG_05359	A6QS49	A6R6V1	Uncharacterized protein.	Uncharacterized protein.	0.425
HCAG_00205	HCAG_06013	A6QS49	A6RAM5	Uncharacterized protein.	Cytochrome P450 61; Belongs to the cytochrome P450 family.	0.648
HCAG_00205	HCAG_06888	A6QS49	A6R997	Uncharacterized protein.	C-5 sterol desaturase; Belongs to the sterol desaturase family.	0.930
HCAG_00205	HCAG_06936	A6QS49	A6R9E5	Uncharacterized protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.458
HCAG_00205	HCAG_06937	A6QS49	A6R9E6	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.425
HCAG_00205	HCAG_07071	A6QS49	A6RBR3	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.558
HCAG_00205	HCAG_07128	A6QS49	A6RBX0	Uncharacterized protein.	Uncharacterized protein.	0.870