(12 nodes) Endoplasmic reticulum lumen, and Protein folding in endoplasmic reticulum network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_02037	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (432 aa)
	HCAG_02804	Uncharacterized protein. (614 aa)
	HCAG_03630	Protein disulfide-isomerase. (540 aa)
	HCAG_04400	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1114 aa)
	HCAG_04802	Thioredoxin domain-containing protein. (485 aa)
	HCAG_05392	Uncharacterized protein. (1752 aa)
	HCAG_06817	Uncharacterized protein. (787 aa)
	HCAG_05805	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family. (677 aa)
	HCAG_06060	Uncharacterized protein. (543 aa)
	HCAG_07372	Uncharacterized protein. (415 aa)
	HCAG_08726	Thioredoxin domain-containing protein. (720 aa)
	HCAG_09066	J domain-containing protein. (323 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_02037	HCAG_02804	A6QXD0	A6QZJ7	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Uncharacterized protein.	0.882
HCAG_02037	HCAG_04400	A6QXD0	A6R442	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.671
HCAG_02037	HCAG_04802	A6QXD0	A6R594	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Thioredoxin domain-containing protein.	0.425
HCAG_02037	HCAG_05805	A6QXD0	A6RA17	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.932
HCAG_02037	HCAG_06060	A6QXD0	A6RAS2	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Uncharacterized protein.	0.834
HCAG_02037	HCAG_06817	A6QXD0	A6R926	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Uncharacterized protein.	0.634
HCAG_02037	HCAG_08726	A6QXD0	A6RGF9	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Thioredoxin domain-containing protein.	0.425
HCAG_02804	HCAG_02037	A6QZJ7	A6QXD0	Uncharacterized protein.	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	0.882
HCAG_02804	HCAG_03630	A6QZJ7	A6R1X2	Uncharacterized protein.	Protein disulfide-isomerase.	0.998
HCAG_02804	HCAG_04400	A6QZJ7	A6R442	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.441
HCAG_02804	HCAG_04802	A6QZJ7	A6R594	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.964
HCAG_02804	HCAG_05805	A6QZJ7	A6RA17	Uncharacterized protein.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.767
HCAG_02804	HCAG_06060	A6QZJ7	A6RAS2	Uncharacterized protein.	Uncharacterized protein.	0.596
HCAG_02804	HCAG_06817	A6QZJ7	A6R926	Uncharacterized protein.	Uncharacterized protein.	0.554
HCAG_02804	HCAG_08726	A6QZJ7	A6RGF9	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.975
HCAG_02804	HCAG_09066	A6QZJ7	A6RHE9	Uncharacterized protein.	J domain-containing protein.	0.450
HCAG_03630	HCAG_02804	A6R1X2	A6QZJ7	Protein disulfide-isomerase.	Uncharacterized protein.	0.998
HCAG_03630	HCAG_04400	A6R1X2	A6R442	Protein disulfide-isomerase.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.735
HCAG_03630	HCAG_04802	A6R1X2	A6R594	Protein disulfide-isomerase.	Thioredoxin domain-containing protein.	0.641
HCAG_03630	HCAG_05392	A6R1X2	A6R6Y4	Protein disulfide-isomerase.	Uncharacterized protein.	0.401