(12 nodes) VCP-NPL4-UFD1 AAA ATPase complex, and KEAP1-NFE2L2 pathway network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00738	Uncharacterized protein. (788 aa)
	HCAG_02080	Uncharacterized protein. (361 aa)
	HCAG_02452	Cell division cycle protein 48; Belongs to the AAA ATPase family. (806 aa)
	HCAG_02977	DUF4203 domain-containing protein. (920 aa)
	HCAG_03521	OTU domain-containing protein. (354 aa)
	HCAG_03965	AAA domain-containing protein. (914 aa)
	HCAG_04186	TUG-UBL1 domain-containing protein. (485 aa)
	NPL4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (642 aa)
	HCAG_05567	U-box domain-containing protein. (1058 aa)
	HCAG_06392	UBX domain-containing protein. (591 aa)
	HCAG_07684	AZUL domain-containing protein. (810 aa)
	HCAG_08503	Uncharacterized protein. (712 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00738	HCAG_02080	A6QTN2	A6QXH3	Uncharacterized protein.	Uncharacterized protein.	0.979
HCAG_00738	HCAG_02452	A6QTN2	A6QYJ5	Uncharacterized protein.	Cell division cycle protein 48; Belongs to the AAA ATPase family.	0.979
HCAG_00738	HCAG_02977	A6QTN2	A6R020	Uncharacterized protein.	DUF4203 domain-containing protein.	0.802
HCAG_00738	HCAG_03521	A6QTN2	A6R1L3	Uncharacterized protein.	OTU domain-containing protein.	0.976
HCAG_00738	HCAG_03965	A6QTN2	A6R2V7	Uncharacterized protein.	AAA domain-containing protein.	0.493
HCAG_00738	HCAG_04186	A6QTN2	A6R3H8	Uncharacterized protein.	TUG-UBL1 domain-containing protein.	0.595
HCAG_00738	HCAG_05567	A6QTN2	A6R7F9	Uncharacterized protein.	U-box domain-containing protein.	0.704
HCAG_00738	HCAG_06392	A6QTN2	A6R7V1	Uncharacterized protein.	UBX domain-containing protein.	0.497
HCAG_00738	HCAG_07684	A6QTN2	A6RDH6	Uncharacterized protein.	AZUL domain-containing protein.	0.802
HCAG_00738	HCAG_08503	A6QTN2	A6RFT7	Uncharacterized protein.	Uncharacterized protein.	0.493
HCAG_00738	NPL4	A6QTN2	A6R538	Uncharacterized protein.	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	0.979
HCAG_02080	HCAG_00738	A6QXH3	A6QTN2	Uncharacterized protein.	Uncharacterized protein.	0.979
HCAG_02080	HCAG_02452	A6QXH3	A6QYJ5	Uncharacterized protein.	Cell division cycle protein 48; Belongs to the AAA ATPase family.	0.997
HCAG_02080	HCAG_03521	A6QXH3	A6R1L3	Uncharacterized protein.	OTU domain-containing protein.	0.973
HCAG_02080	HCAG_03965	A6QXH3	A6R2V7	Uncharacterized protein.	AAA domain-containing protein.	0.459
HCAG_02080	HCAG_04186	A6QXH3	A6R3H8	Uncharacterized protein.	TUG-UBL1 domain-containing protein.	0.488
HCAG_02080	HCAG_05567	A6QXH3	A6R7F9	Uncharacterized protein.	U-box domain-containing protein.	0.974
HCAG_02080	HCAG_06392	A6QXH3	A6R7V1	Uncharacterized protein.	UBX domain-containing protein.	0.981
HCAG_02080	HCAG_08503	A6QXH3	A6RFT7	Uncharacterized protein.	Uncharacterized protein.	0.459
HCAG_02080	NPL4	A6QXH3	A6R538	Uncharacterized protein.	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	0.999