(5 nodes) Sensing of DNA Double Strand Breaks network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_02557	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (792 aa)
	HCAG_06081	AAA_23 domain-containing protein. (1261 aa)
	HCAG_07664	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2465 aa)
	HCAG_07917	FHA domain-containing protein. (612 aa)
	HCAG_08365	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (782 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_02557	HCAG_06081	A6QYV0	A6RAU3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA_23 domain-containing protein.	0.968
HCAG_02557	HCAG_07664	A6QYV0	A6RDF6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.997
HCAG_02557	HCAG_07917	A6QYV0	A6RE52	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FHA domain-containing protein.	0.990
HCAG_02557	HCAG_08365	A6QYV0	A6RFE9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.934
HCAG_06081	HCAG_02557	A6RAU3	A6QYV0	AAA_23 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.968
HCAG_06081	HCAG_07664	A6RAU3	A6RDF6	AAA_23 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.932
HCAG_06081	HCAG_07917	A6RAU3	A6RE52	AAA_23 domain-containing protein.	FHA domain-containing protein.	0.996
HCAG_06081	HCAG_08365	A6RAU3	A6RFE9	AAA_23 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
HCAG_07664	HCAG_02557	A6RDF6	A6QYV0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.997
HCAG_07664	HCAG_06081	A6RDF6	A6RAU3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA_23 domain-containing protein.	0.932
HCAG_07664	HCAG_07917	A6RDF6	A6RE52	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FHA domain-containing protein.	0.919
HCAG_07664	HCAG_08365	A6RDF6	A6RFE9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.871
HCAG_07917	HCAG_02557	A6RE52	A6QYV0	FHA domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.990
HCAG_07917	HCAG_06081	A6RE52	A6RAU3	FHA domain-containing protein.	AAA_23 domain-containing protein.	0.996
HCAG_07917	HCAG_07664	A6RE52	A6RDF6	FHA domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.919
HCAG_07917	HCAG_08365	A6RE52	A6RFE9	FHA domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.965
HCAG_08365	HCAG_02557	A6RFE9	A6QYV0	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.934
HCAG_08365	HCAG_06081	A6RFE9	A6RAU3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	AAA_23 domain-containing protein.	0.998
HCAG_08365	HCAG_07664	A6RFE9	A6RDF6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.871
HCAG_08365	HCAG_07917	A6RFE9	A6RE52	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	FHA domain-containing protein.	0.965