(5 nodes) Osmosensory signaling pathway network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SHO1	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (292 aa)
	HCAG_02220	Protein kinase domain-containing protein. (668 aa)
	HCAG_02453	Uncharacterized protein. (435 aa)
	HCAG_08908	Opy2 domain-containing protein. (428 aa)
	HCAG_09047	Uncharacterized protein. (898 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_02220	HCAG_02453	A6QXW3	A6QYJ6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.557
HCAG_02220	HCAG_08908	A6QXW3	A6RGZ1	Protein kinase domain-containing protein.	Opy2 domain-containing protein.	0.438
HCAG_02220	HCAG_09047	A6QXW3	A6RHD0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.980
HCAG_02220	SHO1	A6QXW3	A6QTM4	Protein kinase domain-containing protein.	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.995
HCAG_02453	HCAG_02220	A6QYJ6	A6QXW3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.557
HCAG_02453	HCAG_08908	A6QYJ6	A6RGZ1	Uncharacterized protein.	Opy2 domain-containing protein.	0.966
HCAG_02453	HCAG_09047	A6QYJ6	A6RHD0	Uncharacterized protein.	Uncharacterized protein.	0.994
HCAG_02453	SHO1	A6QYJ6	A6QTM4	Uncharacterized protein.	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.967
HCAG_08908	HCAG_02220	A6RGZ1	A6QXW3	Opy2 domain-containing protein.	Protein kinase domain-containing protein.	0.438
HCAG_08908	HCAG_02453	A6RGZ1	A6QYJ6	Opy2 domain-containing protein.	Uncharacterized protein.	0.966
HCAG_08908	HCAG_09047	A6RGZ1	A6RHD0	Opy2 domain-containing protein.	Uncharacterized protein.	0.445
HCAG_08908	SHO1	A6RGZ1	A6QTM4	Opy2 domain-containing protein.	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.673
HCAG_09047	HCAG_02220	A6RHD0	A6QXW3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.980
HCAG_09047	HCAG_02453	A6RHD0	A6QYJ6	Uncharacterized protein.	Uncharacterized protein.	0.994
HCAG_09047	HCAG_08908	A6RHD0	A6RGZ1	Uncharacterized protein.	Opy2 domain-containing protein.	0.445
HCAG_09047	SHO1	A6RHD0	A6QTM4	Uncharacterized protein.	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.969
SHO1	HCAG_02220	A6QTM4	A6QXW3	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Protein kinase domain-containing protein.	0.995
SHO1	HCAG_02453	A6QTM4	A6QYJ6	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Uncharacterized protein.	0.967
SHO1	HCAG_08908	A6QTM4	A6RGZ1	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Opy2 domain-containing protein.	0.673
SHO1	HCAG_09047	A6QTM4	A6RHD0	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Uncharacterized protein.	0.969