(16 nodes) Mixed, incl. Magnesium-dependent protein serine/threonine phosphatase complex, and Serine/Threonine protein phosphatase PP2A-like network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00216	Protein phosphatase PP2A regulatory subunit A. (613 aa)
	HCAG_00424	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (734 aa)
	HCAG_00709	Metallophos domain-containing protein. (505 aa)
	HCAG_00867	Serine/threonine-protein phosphatase. (322 aa)
	HCAG_02631	Serine/threonine-protein phosphatase. (362 aa)
	HCAG_02660	Uncharacterized protein. (353 aa)
	HCAG_02846	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (381 aa)
	HCAG_02971	SMK-1 domain-containing protein. (962 aa)
	HCAG_04749	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (415 aa)
	HCAG_04969	Serine/threonine-protein phosphatase. (329 aa)
	HCAG_05026	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (446 aa)
	HCAG_06717	Uncharacterized protein. (1087 aa)
	HCAG_05771	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (474 aa)
	HCAG_06083	Uncharacterized protein. (503 aa)
	HCAG_07438	Uncharacterized protein. (106 aa)
	HCAG_08368	Serine/threonine-protein phosphatase. (307 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00216	HCAG_00424	A6QS60	A6QSR8	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.999
HCAG_00216	HCAG_00709	A6QS60	A6QTK3	Protein phosphatase PP2A regulatory subunit A.	Metallophos domain-containing protein.	0.952
HCAG_00216	HCAG_00867	A6QS60	A6QU11	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.821
HCAG_00216	HCAG_02631	A6QS60	A6QZ24	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.881
HCAG_00216	HCAG_02660	A6QS60	A6QZ53	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.636
HCAG_00216	HCAG_02846	A6QS60	A6QZN9	Protein phosphatase PP2A regulatory subunit A.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.999
HCAG_00216	HCAG_04749	A6QS60	A6R541	Protein phosphatase PP2A regulatory subunit A.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.968
HCAG_00216	HCAG_04969	A6QS60	A6R5R1	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.999
HCAG_00216	HCAG_05026	A6QS60	A6R5W8	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.	0.825
HCAG_00216	HCAG_05771	A6QS60	A6R9Y3	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.	0.820
HCAG_00216	HCAG_06083	A6QS60	A6RAU5	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.643
HCAG_00216	HCAG_06717	A6QS60	A6R8S6	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.741
HCAG_00216	HCAG_07438	A6QS60	A6RCT0	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.519
HCAG_00216	HCAG_08368	A6QS60	A6RFF2	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.907
HCAG_00424	HCAG_00216	A6QSR8	A6QS60	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Protein phosphatase PP2A regulatory subunit A.	0.999
HCAG_00424	HCAG_00709	A6QSR8	A6QTK3	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Metallophos domain-containing protein.	0.948
HCAG_00424	HCAG_00867	A6QSR8	A6QU11	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase.	0.757
HCAG_00424	HCAG_02631	A6QSR8	A6QZ24	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Serine/threonine-protein phosphatase.	0.823
HCAG_00424	HCAG_02660	A6QSR8	A6QZ53	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Uncharacterized protein.	0.549
HCAG_00424	HCAG_02846	A6QSR8	A6QZN9	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.979