(38 nodes) Small-subunit processome, and Endonucleolytic cleavage in 5-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00460	Periodic tryptophan protein 2. (935 aa)
	HCAG_00750	U3 small nucleolar ribonucleoprotein protein IMP4. (315 aa)
	HCAG_00829	Uncharacterized protein. (904 aa)
	HCAG_01259	Nucleolar essential protein 1. (258 aa)
	HCAG_01688	Utp12 domain-containing protein. (905 aa)
	HCAG_01788	Sas10 domain-containing protein. (737 aa)
	HCAG_02340	Fibrillarin. (213 aa)
	HCAG_02358	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (268 aa)
	NOP58	Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (635 aa)
	HCAG_02441	WD_REPEATS_REGION domain-containing protein. (328 aa)
	HCAG_02749	Uncharacterized protein. (227 aa)
	HCAG_02827	CBF domain-containing protein. (428 aa)
	HCAG_03539	U3 small nucleolar RNA-associated protein 22. (1060 aa)
	HCAG_03549	WD_REPEATS_REGION domain-containing protein. (1029 aa)
	HCAG_03776	WD_REPEATS_REGION domain-containing protein. (545 aa)
	HCAG_04171	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
	HCAG_04197	WD_REPEATS_REGION domain-containing protein. (641 aa)
	HCAG_04202	WD_REPEATS_REGION domain-containing protein. (957 aa)
	HCAG_04413	Uncharacterized protein. (316 aa)
	HCAG_04707	WD_REPEATS_REGION domain-containing protein. (961 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1068 aa)
	HCAG_05164	Uncharacterized protein. (1175 aa)
	HCAG_05421	Nop domain-containing protein. (483 aa)
	HCAG_05422	NOP5NT domain-containing protein. (185 aa)
	HCAG_05451	Uncharacterized protein. (398 aa)
	HCAG_06909	Fcf2 domain-containing protein. (238 aa)
	HCAG_05783	Uncharacterized protein. (521 aa)
	HCAG_05816	NUC153 domain-containing protein. (662 aa)
	HCAG_05902	Uncharacterized protein. (2307 aa)
	HCAG_05984	Ribosome biogenesis protein BMS1. (1039 aa)
	HCAG_06029	Uncharacterized protein. (900 aa)
	HCAG_07125	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (334 aa)
	HCAG_07279	Uncharacterized protein. (566 aa)
	HCAG_07649	PINc domain-containing protein. (197 aa)
	HCAG_07980	WD_REPEATS_REGION domain-containing protein. (1041 aa)
	HCAG_08614	Uncharacterized protein. (405 aa)
	HCAG_08862	WD_REPEATS_REGION domain-containing protein. (571 aa)
	HCAG_09276	WD_REPEATS_REGION domain-containing protein. (239 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00460	HCAG_00750	A6QSV4	A6QTP4	Periodic tryptophan protein 2.	U3 small nucleolar ribonucleoprotein protein IMP4.	0.996
HCAG_00460	HCAG_00829	A6QSV4	A6QTX3	Periodic tryptophan protein 2.	Uncharacterized protein.	0.998
HCAG_00460	HCAG_01259	A6QSV4	A6QV52	Periodic tryptophan protein 2.	Nucleolar essential protein 1.	0.993
HCAG_00460	HCAG_01688	A6QSV4	A6QWD1	Periodic tryptophan protein 2.	Utp12 domain-containing protein.	0.999
HCAG_00460	HCAG_01788	A6QSV4	A6QWN1	Periodic tryptophan protein 2.	Sas10 domain-containing protein.	0.994
HCAG_00460	HCAG_02340	A6QSV4	A6QY83	Periodic tryptophan protein 2.	Fibrillarin.	0.996
HCAG_00460	HCAG_02358	A6QSV4	A6QYA1	Periodic tryptophan protein 2.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.989
HCAG_00460	HCAG_02441	A6QSV4	A6QYI4	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.991
HCAG_00460	HCAG_02749	A6QSV4	A6QZE2	Periodic tryptophan protein 2.	Uncharacterized protein.	0.997
HCAG_00460	HCAG_02827	A6QSV4	A6QZM0	Periodic tryptophan protein 2.	CBF domain-containing protein.	0.997
HCAG_00460	HCAG_03539	A6QSV4	A6R1N1	Periodic tryptophan protein 2.	U3 small nucleolar RNA-associated protein 22.	0.999
HCAG_00460	HCAG_03549	A6QSV4	A6R1P1	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_03776	A6QSV4	A6R2B8	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.998
HCAG_00460	HCAG_04171	A6QSV4	A6R3G3	Periodic tryptophan protein 2.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.941
HCAG_00460	HCAG_04197	A6QSV4	A6R3I9	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.998
HCAG_00460	HCAG_04202	A6QSV4	A6R3J4	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_04413	A6QSV4	A6R455	Periodic tryptophan protein 2.	Uncharacterized protein.	0.997
HCAG_00460	HCAG_04707	A6QSV4	A6R4Z9	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_05164	A6QSV4	A6R6A6	Periodic tryptophan protein 2.	Uncharacterized protein.	0.990
HCAG_00460	HCAG_05421	A6QSV4	A6R713	Periodic tryptophan protein 2.	Nop domain-containing protein.	0.914