(18 nodes) 90S preribosome, and t-UTP complex network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00460	Periodic tryptophan protein 2. (935 aa)
	HCAG_00750	U3 small nucleolar ribonucleoprotein protein IMP4. (315 aa)
	HCAG_01688	Utp12 domain-containing protein. (905 aa)
	HCAG_02749	Uncharacterized protein. (227 aa)
	HCAG_03539	U3 small nucleolar RNA-associated protein 22. (1060 aa)
	HCAG_03549	WD_REPEATS_REGION domain-containing protein. (1029 aa)
	HCAG_04202	WD_REPEATS_REGION domain-containing protein. (957 aa)
	HCAG_04413	Uncharacterized protein. (316 aa)
	HCAG_04707	WD_REPEATS_REGION domain-containing protein. (961 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1068 aa)
	HCAG_05451	Uncharacterized protein. (398 aa)
	HCAG_05783	Uncharacterized protein. (521 aa)
	HCAG_05816	NUC153 domain-containing protein. (662 aa)
	HCAG_05984	Ribosome biogenesis protein BMS1. (1039 aa)
	HCAG_07980	WD_REPEATS_REGION domain-containing protein. (1041 aa)
	HCAG_08614	Uncharacterized protein. (405 aa)
	HCAG_08862	WD_REPEATS_REGION domain-containing protein. (571 aa)
	HCAG_09276	WD_REPEATS_REGION domain-containing protein. (239 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00460	HCAG_00750	A6QSV4	A6QTP4	Periodic tryptophan protein 2.	U3 small nucleolar ribonucleoprotein protein IMP4.	0.996
HCAG_00460	HCAG_01688	A6QSV4	A6QWD1	Periodic tryptophan protein 2.	Utp12 domain-containing protein.	0.999
HCAG_00460	HCAG_02749	A6QSV4	A6QZE2	Periodic tryptophan protein 2.	Uncharacterized protein.	0.997
HCAG_00460	HCAG_03539	A6QSV4	A6R1N1	Periodic tryptophan protein 2.	U3 small nucleolar RNA-associated protein 22.	0.999
HCAG_00460	HCAG_03549	A6QSV4	A6R1P1	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_04202	A6QSV4	A6R3J4	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_04413	A6QSV4	A6R455	Periodic tryptophan protein 2.	Uncharacterized protein.	0.997
HCAG_00460	HCAG_04707	A6QSV4	A6R4Z9	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_05451	A6QSV4	A6R743	Periodic tryptophan protein 2.	Uncharacterized protein.	0.999
HCAG_00460	HCAG_05783	A6QSV4	A6R9Z5	Periodic tryptophan protein 2.	Uncharacterized protein.	0.991
HCAG_00460	HCAG_05816	A6QSV4	A6RA28	Periodic tryptophan protein 2.	NUC153 domain-containing protein.	0.996
HCAG_00460	HCAG_05984	A6QSV4	A6RAJ6	Periodic tryptophan protein 2.	Ribosome biogenesis protein BMS1.	0.998
HCAG_00460	HCAG_07980	A6QSV4	A6REB5	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	HCAG_08614	A6QSV4	A6RG48	Periodic tryptophan protein 2.	Uncharacterized protein.	0.996
HCAG_00460	HCAG_08862	A6QSV4	A6RGU5	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.998
HCAG_00460	HCAG_09276	A6QSV4	A6XPH1	Periodic tryptophan protein 2.	WD_REPEATS_REGION domain-containing protein.	0.999
HCAG_00460	NAT10	A6QSV4	A6R595	Periodic tryptophan protein 2.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.999
HCAG_00750	HCAG_00460	A6QTP4	A6QSV4	U3 small nucleolar ribonucleoprotein protein IMP4.	Periodic tryptophan protein 2.	0.996
HCAG_00750	HCAG_01688	A6QTP4	A6QWD1	U3 small nucleolar ribonucleoprotein protein IMP4.	Utp12 domain-containing protein.	0.994
HCAG_00750	HCAG_02749	A6QTP4	A6QZE2	U3 small nucleolar ribonucleoprotein protein IMP4.	Uncharacterized protein.	0.995