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| | HCAG_00014 | Homoserine dehydrogenase. (370 aa) |
| | HCAG_00060 | Uncharacterized protein. (451 aa) |
| | HCAG_00104 | Acetolactate synthase. (610 aa) |
| | HCAG_00290 | Chorismate mutase. (269 aa) |
| | HCAG_00293 | APH domain-containing protein. (322 aa) |
| | HCAG_00386 | Cysteine synthase. (377 aa) |
| | HCAG_00428 | Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa) |
| | HCAG_00436 | Elongation of fatty acids protein. (193 aa) |
| | HCAG_00444 | Methyltranfer_dom domain-containing protein. (463 aa) |
| | HCAG_00474 | Aminotran_1_2 domain-containing protein. (641 aa) |
| | HCAG_00487 | GTP cyclohydrolase I. (390 aa) |
| | HCAG_00512 | Uncharacterized protein. (245 aa) |
| | HCAG_00526 | AMP-binding domain-containing protein. (436 aa) |
| | HCAG_00531 | Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (344 aa) |
| | HCAG_00541 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (712 aa) |
| | HCAG_00564 | Alpha-methylacyl-CoA racemase. (398 aa) |
| | HCAG_00648 | Uncharacterized protein. (323 aa) |
| | HCAG_00712 | AB hydrolase-1 domain-containing protein. (564 aa) |
| | HCAG_00742 | Guanine nucleotide-binding protein alpha subunit. (353 aa) |
| | HCAG_00748 | Anthranilate synthase component II. (652 aa) |
| | HCAG_00793 | Threonine synthase. (536 aa) |
| | HCAG_00798 | Uncharacterized protein. (485 aa) |
| | HCAG_00837 | MFS domain-containing protein. (475 aa) |
| | HCAG_00921 | Pantoate--beta-alanine ligase. (363 aa) |
| | HCAG_01026 | Uncharacterized protein. (867 aa) |
| | HCAG_01100 | Uncharacterized protein. (1324 aa) |
| | HCAG_01145 | Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (376 aa) |
| | HCAG_01191 | ApbA domain-containing protein. (149 aa) |
| | MET3 | Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa) |
| | HCAG_01216 | PAPS_reduct domain-containing protein. (300 aa) |
| | HCAG_01217 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (465 aa) |
| | HCAG_01298 | Aminotran_1_2 domain-containing protein. (481 aa) |
| | HCAG_01309 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (108 aa) |
| | HCAG_01322 | Uncharacterized protein. (515 aa) |
| | HCAG_01393 | Uncharacterized protein; Belongs to the cytochrome P450 family. (434 aa) |
| | HCAG_01397 | Ferredoxin-dependent glutamate synthase 1. (1469 aa) |
| | HCAG_01437 | Homoserine O-acetyltransferase. (511 aa) |
| | HCAG_01497 | Uncharacterized protein. (454 aa) |
| | HCAG_01500 | Glu_synthase domain-containing protein. (415 aa) |
| | HCAG_01575 | Saccharopine dehydrogenase. (457 aa) |
| | HCAG_01643 | Uncharacterized protein. (450 aa) |
| | HCAG_01655 | Aminotran_1_2 domain-containing protein. (420 aa) |
| | HCAG_01669 | Uncharacterized protein. (1030 aa) |
| | HCAG_01670 | S5A_REDUCTASE domain-containing protein. (197 aa) |
| | HCAG_01742 | Adenylyl-sulfate kinase. (155 aa) |
| | HCAG_01779 | DUF2236 domain-containing protein. (446 aa) |
| | HCAG_01842 | PKS_ER domain-containing protein. (270 aa) |
| | HCAG_01939 | Carbamoyl-phosphate synthase arginine-specific small chain, mitochondrial. (471 aa) |
| | HCAG_02035 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (549 aa) |
| | HCAG_02122 | Uncharacterized protein. (276 aa) |
| | HCAG_02124 | Semialdhyde_dh domain-containing protein. (338 aa) |
| | HCAG_02169 | Elongation of fatty acids protein. (548 aa) |
| | HCAG_02256 | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (385 aa) |
| | HCAG_02260 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa) |
| | HCAG_02357 | Histidinol dehydrogenase. (1148 aa) |
| | HCAG_02371 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (478 aa) |
| | HCAG_02700 | Carbamoyl-phosphate synthase arginine-specific large chain. (1182 aa) |
| | HCAG_02710 | Cystathionine gamma-lyase. (457 aa) |
| | HCAG_02734 | Uncharacterized protein. (361 aa) |
| | BNA1 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (192 aa) |
| | HCAG_02799 | Cysteine synthase 2. (409 aa) |
| | HCAG_02994 | Pyridoxal biosynthesis lyase pdxS; Belongs to the PdxS/SNZ family. (320 aa) |
| | HCAG_02997 | Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (471 aa) |
| | HCAG_03049 | MaoC-like domain-containing protein. (364 aa) |
| | HCAG_03050 | Uncharacterized protein. (344 aa) |
| | HCAG_03101 | Aspartokinase. (518 aa) |
| | HCAG_03111 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (488 aa) |
| | HCAG_03148 | Uncharacterized protein. (1206 aa) |
| | HCAG_03184 | Uncharacterized protein; Belongs to the cytochrome P450 family. (471 aa) |
| | HCAG_03270 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (374 aa) |
| | HCAG_03271 | Uncharacterized protein. (1317 aa) |
| | HCAG_03326 | Imidazoleglycerol-phosphate dehydratase. (609 aa) |
| | HCAG_03447 | Glutamine amidotransferase type-2 domain-containing protein. (747 aa) |
| | HCAG_03540 | Cystathionine gamma-synthase. (606 aa) |
| | HCAG_03622 | Uncharacterized protein. (237 aa) |
| | HCAG_03750 | DJ-1_PfpI domain-containing protein. (240 aa) |
| | HCAG_03751 | Aspartate aminotransferase. (443 aa) |
| | HCAG_03801 | Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa) |
| | HCAG_03831 | Uncharacterized protein. (475 aa) |
| | HCAG_03900 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (332 aa) |
| | HCAG_03936 | Uncharacterized protein. (763 aa) |
| | HCAG_04000 | Dihydroxy-acid dehydratase. (611 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (391 aa) |
| | HCAG_04217 | APH domain-containing protein. (274 aa) |
| | HCAG_04512 | Uncharacterized protein. (331 aa) |
| | HCAG_04514 | Beta_elim_lyase domain-containing protein. (393 aa) |
| | HCAG_04541 | Uncharacterized protein. (198 aa) |
| | HCAG_04577 | Dihydroxy-acid dehydratase. (499 aa) |
| | HCAG_04617 | Amino transferase. (532 aa) |
| | HCAG_04689 | BTB domain-containing protein. (364 aa) |
| | HCAG_04744 | Uncharacterized protein. (209 aa) |
| | HCAG_04747 | Uncharacterized protein. (484 aa) |
| | HCAG_04760 | Uncharacterized protein. (83 aa) |
| | HCAG_04817 | Uncharacterized protein; Belongs to the cytochrome P450 family. (619 aa) |
| | HCAG_04924 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (362 aa) |
| | HCAG_04933 | Uncharacterized protein. (486 aa) |
| | HCAG_04999 | Spermidine synthase; Belongs to the spermidine/spermine synthase family. (292 aa) |
| | HCAG_05073 | Protein arg-6, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family. (898 aa) |
| | HCAG_05092 | Uncharacterized protein. (713 aa) |
| | HCAG_05202 | Uncharacterized protein. (1116 aa) |
| | HCAG_05224 | Anthranilate synthase component I. (511 aa) |
| | HCAG_05244 | Uncharacterized protein. (264 aa) |
| | HCAG_05249 | Uncharacterized protein. (267 aa) |
| | HCAG_05359 | Uncharacterized protein. (170 aa) |
| | HCAG_05408 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (314 aa) |
| | HCAG_05497 | Neutral ceramidase. (715 aa) |
| | HCAG_05510 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (141 aa) |
| | HCAG_05540 | M20_dimer domain-containing protein. (332 aa) |
| | HCAG_05546 | Chorismate synthase. (407 aa) |
| | HCAG_05565 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (763 aa) |
| | HCAG_05584 | Mitochondrial acetolactate synthase small subunit. (336 aa) |
| | HCAG_05587 | Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (346 aa) |
| | HCAG_05619 | Uncharacterized protein. (539 aa) |
| | HCAG_05620 | Glutamine amidotransferase type-2 domain-containing protein. (269 aa) |
| | HCAG_05651 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (351 aa) |
| | HCAG_06360 | ATP phosphoribosyltransferase. (324 aa) |
| | HCAG_06386 | AP_endonuc_2 domain-containing protein. (406 aa) |
| | HCAG_06493 | Uncharacterized protein. (307 aa) |
| | HCAG_06569 | Uncharacterized protein. (322 aa) |
| | HCAG_06683 | Uncharacterized protein. (410 aa) |
| | HCAG_06699 | 3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1538 aa) |
| | HCAG_06729 | Histidinol-phosphate aminotransferase. (321 aa) |
| | HCAG_06854 | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (797 aa) |
| | HCAG_06856 | Uncharacterized protein. (434 aa) |
| | HCAG_06937 | Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa) |
| | HCAG_07004 | O-acetylhomoserine. (441 aa) |
| | HCAG_05725 | Biotin synthase. (398 aa) |
| | HCAG_05726 | Uncharacterized protein. (660 aa) |
| | HCAG_05768 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (311 aa) |
| | HCAG_05833 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (337 aa) |
| | HCAG_05953 | Tryptophan synthase. (600 aa) |
| | HCAG_05962 | Aminotran_5 domain-containing protein. (422 aa) |
| | HCAG_06024 | Fe-ADH domain-containing protein. (205 aa) |
| | MDE1 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (240 aa) |
| | HCAG_06098 | Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (417 aa) |
| | HCAG_06126 | AB hydrolase-1 domain-containing protein. (462 aa) |
| | HCAG_06128 | DJ-1_PfpI domain-containing protein. (232 aa) |
| | HCAG_06162 | Aminotran_5 domain-containing protein. (327 aa) |
| | HCAG_06163 | Uncharacterized protein. (64 aa) |
| | HCAG_06191 | Uncharacterized protein. (388 aa) |
| | HCAG_06194 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (450 aa) |
| | HCAG_06199 | Uncharacterized protein. (200 aa) |
| | HCAG_06205 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa) |
| | HCAG_06253 | Threonine dehydratase. (540 aa) |
| | HCAG_06298 | Methyltransf_33 domain-containing protein. (285 aa) |
| | HCAG_07028 | Gln_synt_b-grasp domain-containing protein; Belongs to the glutamine synthetase family. (210 aa) |
| | HCAG_07104 | 3-isopropylmalate dehydratase. (714 aa) |
| | HCAG_07107 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (619 aa) |
| | HCAG_07124 | AMP-binding domain-containing protein. (598 aa) |
| | HCAG_07127 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa) |
| | ARG2 | Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (684 aa) |
| | HCAG_07205 | Beta_elim_lyase domain-containing protein. (418 aa) |
| | HCAG_07225 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (229 aa) |
| | HCAG_07273 | N-acetyltransferase domain-containing protein. (208 aa) |
| | HCAG_07295 | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (426 aa) |
| | HCAG_07330 | Uncharacterized protein. (892 aa) |
| | HCAG_07331 | Uncharacterized protein. (1003 aa) |
| | HCAG_07339 | ACPS domain-containing protein. (432 aa) |
| | HCAG_07418 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (519 aa) |
| | HCAG_07434 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (498 aa) |
| | HCAG_07435 | Glutamate 5-kinase. (507 aa) |
| | HCAG_07450 | Uncharacterized protein. (307 aa) |
| | HCAG_07464 | Gamma-glutamyl phosphate reductase. (365 aa) |
| | HCAG_07563 | HET domain-containing protein. (743 aa) |
| | HCAG_07607 | Uncharacterized protein. (895 aa) |
| | HCAG_07622 | PKS_ER domain-containing protein. (438 aa) |
| | HCAG_07634 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (374 aa) |
| | HCAG_07636 | Carrier domain-containing protein; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1892 aa) |
| | HCAG_07637 | Fatty acid synthase beta subunit dehydratase; Belongs to the fungal fatty acid synthetase subunit beta family. (2082 aa) |
| | HCAG_07688 | Uncharacterized protein. (222 aa) |
| | HCAG_07692 | Uncharacterized protein. (482 aa) |
| | HCAG_07785 | Homoisocitrate dehydrogenase, mitochondrial. (363 aa) |
| | BNA4 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (510 aa) |
| | HCAG_07804 | AMP-binding domain-containing protein. (666 aa) |
| | HCAG_07805 | Argininosuccinate lyase. (471 aa) |
| | HCAG_07809 | Uncharacterized protein. (410 aa) |
| | HCAG_07844 | Ornithine aminotransferase. (458 aa) |
| | HCAG_07860 | Arrestin_C domain-containing protein. (768 aa) |
| | HCAG_07997 | AB hydrolase-1 domain-containing protein. (411 aa) |
| | HCAG_08023 | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa) |
| | HCAG_08024 | ACPS domain-containing protein. (180 aa) |
| | HCAG_08025 | Uncharacterized protein. (362 aa) |
| | HCAG_08029 | Cystathionine beta-lyase. (447 aa) |
| | HCAG_08076 | Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (396 aa) |
| | HCAG_08085 | Uncharacterized protein. (264 aa) |
| | HCAG_08086 | Uncharacterized protein. (142 aa) |
| | HCAG_08116 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (383 aa) |
| | HCAG_08187 | Folic acid synthesis protein. (590 aa) |
| | HCAG_08220 | Glutamine amidotransferase type-1 domain-containing protein. (834 aa) |
| | HCAG_08223 | AB hydrolase-1 domain-containing protein. (503 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (176 aa) |
| | HCAG_08299 | BRO1 domain-containing protein. (538 aa) |
| | HCAG_08337 | Uncharacterized protein. (224 aa) |
| | HCAG_08357 | Bifunctional pyrimidine biosynthesis protein pyrABCN. (2404 aa) |
| | HCAG_08359 | SGL domain-containing protein. (366 aa) |
| | HCAG_08367 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa) |
| | HCAG_08470 | Threonine aldolase. (374 aa) |
| | HCAG_08550 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (243 aa) |
| | HCAG_08678 | Aspartate aminotransferase. (419 aa) |
| | HCAG_08732 | ACB domain-containing protein. (106 aa) |
| | HCAG_08758 | Uncharacterized protein. (964 aa) |
| | HCAG_08884 | Uncharacterized protein. (321 aa) |
| | HCAG_08889 | PALP domain-containing protein. (411 aa) |
| | HCAG_08890 | Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (433 aa) |
| | HCAG_08926 | Acyl_transf_1 domain-containing protein. (282 aa) |
| | HCAG_08945 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (339 aa) |
| | HCAG_09020 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (603 aa) |
| | HCAG_09068 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (168 aa) |
| | HCAG_09099 | APH domain-containing protein. (365 aa) |
| | HCAG_09191 | Uncharacterized protein. (77 aa) |
