(25 nodes) Oxidoreductase activity, acting on the aldehyde or oxo group of donors network (Histoplasma capsulatum NAm1)

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Your Input:
	HCAG_01025	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (460 aa)
	HCAG_01360	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (405 aa)
	HCAG_01535	2-oxoglutarate dehydrogenase E1 component, mitochondrial. (1054 aa)
	HCAG_01780	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (579 aa)
	HCAG_02053	Uncharacterized protein. (89 aa)
	HCAG_02124	Semialdhyde_dh domain-containing protein. (338 aa)
	HCAG_02371	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (478 aa)
	HCAG_03301	AB hydrolase-1 domain-containing protein. (335 aa)
	HCAG_03314	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (679 aa)
	HCAG_03336	Branched chain alpha-keto acid dehydrogenase E1 subunit beta. (390 aa)
	HCAG_04156	Uncharacterized protein. (637 aa)
	HCAG_04747	Uncharacterized protein. (484 aa)
	HCAG_04910	Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
	HCAG_05073	Protein arg-6, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family. (898 aa)
	HCAG_06845	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (385 aa)
	HCAG_05761	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (450 aa)
	HCAG_06205	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
	HCAG_06245	Succinate-semialdehyde dehydrogenase. (497 aa)
	HCAG_07063	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (527 aa)
	HCAG_07261	Uncharacterized protein. (486 aa)
	HCAG_07464	Gamma-glutamyl phosphate reductase. (365 aa)
	HCAG_07619	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (377 aa)
	HCAG_08153	Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (548 aa)
	HCAG_08367	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
	HCAG_09000	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (585 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01360	HCAG_01535	A6QVF3	A6QVX8	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	0.890
HCAG_01360	HCAG_03336	A6QVF3	A6R129	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Branched chain alpha-keto acid dehydrogenase E1 subunit beta.	0.989
HCAG_01360	HCAG_04910	A6QVF3	A6R5K2	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Glyceraldehyde-3-phosphate dehydrogenase.	0.584
HCAG_01360	HCAG_05761	A6QVF3	A6R9X3	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.697
HCAG_01360	HCAG_07619	A6QVF3	A6RDB1	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
HCAG_01535	HCAG_01360	A6QVX8	A6QVF3	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.890
HCAG_01535	HCAG_03336	A6QVX8	A6R129	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Branched chain alpha-keto acid dehydrogenase E1 subunit beta.	0.801
HCAG_01535	HCAG_04910	A6QVX8	A6R5K2	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Glyceraldehyde-3-phosphate dehydrogenase.	0.609
HCAG_01535	HCAG_05073	A6QVX8	A6R615	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Protein arg-6, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family.	0.440
HCAG_01535	HCAG_05761	A6QVX8	A6R9X3	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.836
HCAG_01535	HCAG_06245	A6QVX8	A6RBA7	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Succinate-semialdehyde dehydrogenase.	0.885
HCAG_01535	HCAG_07063	A6QVX8	A6RBQ5	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.657
HCAG_01535	HCAG_07261	A6QVX8	A6RCA3	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Uncharacterized protein.	0.450
HCAG_01535	HCAG_07464	A6QVX8	A6RCV6	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Gamma-glutamyl phosphate reductase.	0.447
HCAG_01535	HCAG_07619	A6QVX8	A6RDB1	2-oxoglutarate dehydrogenase E1 component, mitochondrial.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.886
HCAG_01780	HCAG_06205	A6QWM3	A6RB67	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.800
HCAG_01780	HCAG_07464	A6QWM3	A6RCV6	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Gamma-glutamyl phosphate reductase.	0.936
HCAG_01780	HCAG_08367	A6QWM3	A6RFF1	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.800
HCAG_01780	HCAG_09000	A6QWM3	A6RH83	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.901
HCAG_02124	HCAG_04910	A6QXL7	A6R5K2	Semialdhyde_dh domain-containing protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.655