(33 nodes) Asexual reproduction network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00594	Hydrophobin. (137 aa)
	HCAG_00742	Guanine nucleotide-binding protein alpha subunit. (353 aa)
	HCAG_00784	Uncharacterized protein. (482 aa)
	HCAG_00852	Serine/threonine-protein kinase nrc-2. (584 aa)
	HCAG_00894	Protein ras-1. (149 aa)
	HCAG_01501	Serine/threonine-protein kinase cot-1. (639 aa)
	HCAG_01774	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1400 aa)
	HCAG_02202	Uncharacterized protein. (445 aa)
	HCAG_02857	Chitin synthase D. (1220 aa)
	HCAG_02940	PH domain-containing protein. (1556 aa)
	HCAG_03019	Non-specific serine/threonine protein kinase. (881 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (530 aa)
	HCAG_03725	Protein dopey. (1788 aa)
	HCAG_04230	Uncharacterized protein. (198 aa)
	HCAG_04331	Uncharacterized protein. (332 aa)
	HCAG_04636	Uncharacterized protein. (325 aa)
	HCAG_04824	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (94 aa)
	HCAG_05077	Uncharacterized protein. (387 aa)
	HCAG_05537	Uncharacterized protein. (902 aa)
	HCAG_06609	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1266 aa)
	HCAG_06674	Conidiophore development protein hymA. (395 aa)
	HCAG_06889	Transcriptional repressor TUP1. (568 aa)
	HCAG_06891	Uncharacterized protein. (639 aa)
	HCAG_05786	BZIP domain-containing protein. (520 aa)
	HCAG_06143	AIP3 domain-containing protein. (1021 aa)
	HCAG_07260	Developmental protein FluG; Belongs to the glutamine synthetase family. (877 aa)
	HCAG_07413	Uncharacterized protein. (508 aa)
	HCAG_07553	Mannan endo-1,6-alpha-mannosidase. (448 aa)
	HCAG_07838	Uncharacterized protein. (685 aa)
	HCAG_09016	Non-specific serine/threonine protein kinase. (904 aa)
	HCAG_08883	Chitin synthase; Plays a major role in cell wall biogenesis. (912 aa)
	HCAG_08842	Chitin synthase; Plays a major role in cell wall biogenesis. (916 aa)
	HCAG_08008	Chitin synthase 2. (1277 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00742	HCAG_00894	A6QTN6	A6QU38	Guanine nucleotide-binding protein alpha subunit.	Protein ras-1.	0.421
HCAG_00742	HCAG_07838	A6QTN6	A6RDY0	Guanine nucleotide-binding protein alpha subunit.	Uncharacterized protein.	0.944
HCAG_00894	HCAG_00742	A6QU38	A6QTN6	Protein ras-1.	Guanine nucleotide-binding protein alpha subunit.	0.421
HCAG_00894	HCAG_03019	A6QU38	A6R062	Protein ras-1.	Non-specific serine/threonine protein kinase.	0.442
HCAG_00894	HCAG_09016	A6QU38	A6RH99	Protein ras-1.	Non-specific serine/threonine protein kinase.	0.442
HCAG_01501	HCAG_06674	A6QVU4	A6R8N3	Serine/threonine-protein kinase cot-1.	Conidiophore development protein hymA.	0.672
HCAG_02202	HCAG_07260	A6QXU5	A6RCA2	Uncharacterized protein.	Developmental protein FluG; Belongs to the glutamine synthetase family.	0.461
HCAG_02202	HCAG_07413	A6QXU5	A6RCQ5	Uncharacterized protein.	Uncharacterized protein.	0.634
HCAG_02202	HCAG_07838	A6QXU5	A6RDY0	Uncharacterized protein.	Uncharacterized protein.	0.475
HCAG_03019	HCAG_00894	A6R062	A6QU38	Non-specific serine/threonine protein kinase.	Protein ras-1.	0.442
HCAG_03019	HCAG_09016	A6R062	A6RH99	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.821
HCAG_06674	HCAG_01501	A6R8N3	A6QVU4	Conidiophore development protein hymA.	Serine/threonine-protein kinase cot-1.	0.672
HCAG_06889	HCAG_07413	A6R998	A6RCQ5	Transcriptional repressor TUP1.	Uncharacterized protein.	0.410
HCAG_07260	HCAG_02202	A6RCA2	A6QXU5	Developmental protein FluG; Belongs to the glutamine synthetase family.	Uncharacterized protein.	0.461
HCAG_07260	HCAG_07838	A6RCA2	A6RDY0	Developmental protein FluG; Belongs to the glutamine synthetase family.	Uncharacterized protein.	0.520
HCAG_07413	HCAG_02202	A6RCQ5	A6QXU5	Uncharacterized protein.	Uncharacterized protein.	0.634
HCAG_07413	HCAG_06889	A6RCQ5	A6R998	Uncharacterized protein.	Transcriptional repressor TUP1.	0.410
HCAG_07838	HCAG_00742	A6RDY0	A6QTN6	Uncharacterized protein.	Guanine nucleotide-binding protein alpha subunit.	0.944
HCAG_07838	HCAG_02202	A6RDY0	A6QXU5	Uncharacterized protein.	Uncharacterized protein.	0.475
HCAG_07838	HCAG_07260	A6RDY0	A6RCA2	Uncharacterized protein.	Developmental protein FluG; Belongs to the glutamine synthetase family.	0.520