(42 nodes) Respiratory electron transport chain network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05593	Uncharacterized protein. (74 aa)
	HCAG_00085	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (643 aa)
	HCAG_00338	zf-CHCC domain-containing protein. (216 aa)
	HCAG_00435	Pyr_redox_2 domain-containing protein. (392 aa)
	HCAG_00437	Uncharacterized protein. (169 aa)
	HCAG_00593	Uncharacterized protein. (142 aa)
	HCAG_00596	Uncharacterized protein. (187 aa)
	HCAG_00943	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (243 aa)
	HCAG_01172	Uncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (128 aa)
	HCAG_01175	Uncharacterized protein. (346 aa)
	HCAG_01568	UCR_hinge domain-containing protein. (126 aa)
	HCAG_01733	NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (160 aa)
	HCAG_02344	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (203 aa)
	HCAG_02655	Uncharacterized protein. (203 aa)
	HCAG_03273	Cytochrome c1. (326 aa)
	HCAG_03426	Uncharacterized protein. (226 aa)
	HCAG_03523	Uncharacterized protein; Belongs to the complex I LYR family. (139 aa)
	HCAG_03761	Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (92 aa)
	HCAG_03875	Uncharacterized protein. (261 aa)
	HCAG_03876	Tafazzin family protein; Belongs to the taffazin family. (238 aa)
	HCAG_04394	Uncharacterized protein. (156 aa)
	HCAG_04409	Uncharacterized protein. (564 aa)
	HCAG_04564	Cytochrome c oxidase polypeptide IV, mitochondrial. (199 aa)
	HCAG_04623	NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (479 aa)
	HCAG_04741	Uncharacterized protein. (323 aa)
	HCAG_05012	Uncharacterized protein. (98 aa)
	HCAG_05509	NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial. (225 aa)
	HCAG_05626	Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (122 aa)
	HCAG_06929	NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial. (756 aa)
	HCAG_06959	Uncharacterized protein. (43 aa)
	HCAG_06996	Uncharacterized protein. (437 aa)
	HCAG_05829	Uncharacterized protein. (614 aa)
	HCAG_05832	Zn(2)-C6 fungal-type domain-containing protein. (457 aa)
	HCAG_05921	Uncharacterized protein. (66 aa)
	HCAG_05938	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	HCAG_06066	Uncharacterized protein. (68 aa)
	HCAG_06317	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (637 aa)
	HCAG_07032	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (308 aa)
	HCAG_07893	Uncharacterized protein. (124 aa)
	HCAG_08313	Pyr_redox_2 domain-containing protein. (455 aa)
	HCAG_08725	Uncharacterized protein. (255 aa)
	HCAG_08885	Cytochrome c oxidase subunit 7A; This small integral protein plays a role in holoenzyme assembly or stability. (62 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00085	HCAG_00943	A6QRS9	A6QU87	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.417
HCAG_00085	HCAG_05509	A6QRS9	A6R7A1	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial.	0.470
HCAG_00085	HCAG_05832	A6QRS9	A6RA44	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	Zn(2)-C6 fungal-type domain-containing protein.	0.472
HCAG_00338	HCAG_00437	A6QSI2	A6QST1	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.971
HCAG_00338	HCAG_00593	A6QSI2	A6QT87	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.484
HCAG_00338	HCAG_00596	A6QSI2	A6QT90	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.667
HCAG_00338	HCAG_00943	A6QSI2	A6QU87	zf-CHCC domain-containing protein.	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.996
HCAG_00338	HCAG_01172	A6QSI2	A6QUW6	zf-CHCC domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family.	0.940
HCAG_00338	HCAG_01175	A6QSI2	A6QUW9	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.697
HCAG_00338	HCAG_01568	A6QSI2	A6QW11	zf-CHCC domain-containing protein.	UCR_hinge domain-containing protein.	0.949
HCAG_00338	HCAG_01733	A6QSI2	A6QWH6	zf-CHCC domain-containing protein.	NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999
HCAG_00338	HCAG_02344	A6QSI2	A6QY87	zf-CHCC domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit.	0.901
HCAG_00338	HCAG_02655	A6QSI2	A6QZ48	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.966
HCAG_00338	HCAG_03273	A6QSI2	A6R0W6	zf-CHCC domain-containing protein.	Cytochrome c1.	0.985
HCAG_00338	HCAG_03426	A6QSI2	A6R1B9	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.667
HCAG_00338	HCAG_03523	A6QSI2	A6R1L5	zf-CHCC domain-containing protein.	Uncharacterized protein; Belongs to the complex I LYR family.	0.999
HCAG_00338	HCAG_03761	A6QSI2	A6R2A3	zf-CHCC domain-containing protein.	Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.	0.853
HCAG_00338	HCAG_04394	A6QSI2	A6R436	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.981
HCAG_00338	HCAG_04409	A6QSI2	A6R451	zf-CHCC domain-containing protein.	Uncharacterized protein.	0.981
HCAG_00338	HCAG_04564	A6QSI2	A6R4K6	zf-CHCC domain-containing protein.	Cytochrome c oxidase polypeptide IV, mitochondrial.	0.990