(18 nodes) Transport vesicle membrane network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06695	Uncharacterized protein. (931 aa)
	HCAG_00157	AP-1 complex subunit gamma. (765 aa)
	HCAG_00598	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family. (422 aa)
	HCAG_01014	Uncharacterized protein. (807 aa)
	HCAG_01154	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
	HCAG_01328	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
	HCAG_01675	t-SNARE coiled-coil homology domain-containing protein. (227 aa)
	HCAG_03764	WD_REPEATS_REGION domain-containing protein. (1265 aa)
	HCAG_03970	Uncharacterized protein. (334 aa)
	HCAG_04225	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1631 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (108 aa)
	HCAG_04789	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (668 aa)
	HCAG_04840	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
	HCAG_05142	Protein transport protein sec22; Belongs to the synaptobrevin family. (215 aa)
	HCAG_05252	Uncharacterized protein. (933 aa)
	HCAG_05443	Uncharacterized protein. (256 aa)
	HCAG_05444	Uncharacterized protein. (667 aa)
	HCAG_08938	Protein transport protein SEC13; Belongs to the WD repeat SEC13 family. (307 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00157	HCAG_00598	A6QS01	A6QT92	AP-1 complex subunit gamma.	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.999
HCAG_00157	HCAG_01154	A6QS01	A6QUU8	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00157	HCAG_01328	A6QS01	A6QVC1	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.876
HCAG_00157	HCAG_04225	A6QS01	A6R3L7	AP-1 complex subunit gamma.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.974
HCAG_00598	HCAG_00157	A6QT92	A6QS01	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.999
HCAG_00598	HCAG_01154	A6QT92	A6QUU8	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00598	HCAG_01328	A6QT92	A6QVC1	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.881
HCAG_00598	HCAG_04225	A6QT92	A6R3L7	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.868
HCAG_01014	HCAG_03764	A6QUF8	A6R2A6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.800
HCAG_01014	HCAG_03970	A6QUF8	A6R2W2	Uncharacterized protein.	Uncharacterized protein.	0.629
HCAG_01014	HCAG_04789	A6QUF8	A6R581	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.748
HCAG_01014	HCAG_04840	A6QUF8	A6R5D2	Uncharacterized protein.	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family.	0.700
HCAG_01014	HCAG_05142	A6QUF8	A6R684	Uncharacterized protein.	Protein transport protein sec22; Belongs to the synaptobrevin family.	0.639
HCAG_01014	HCAG_05252	A6QUF8	A6R6J4	Uncharacterized protein.	Uncharacterized protein.	0.872
HCAG_01014	HCAG_06695	A6QUF8	A6R8Q4	Uncharacterized protein.	Uncharacterized protein.	0.679
HCAG_01014	HCAG_08938	A6QUF8	A6RH21	Uncharacterized protein.	Protein transport protein SEC13; Belongs to the WD repeat SEC13 family.	0.894
HCAG_01154	HCAG_00157	A6QUU8	A6QS01	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit gamma.	0.999
HCAG_01154	HCAG_00598	A6QUU8	A6QT92	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.999
HCAG_01154	HCAG_01328	A6QUU8	A6QVC1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.821
HCAG_01154	HCAG_04225	A6QUU8	A6R3L7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.874