(13 nodes) Preribosome, small subunit precursor network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_01798	Uncharacterized protein. (347 aa)
	HCAG_09041	Uncharacterized protein. (417 aa)
	HCAG_07626	Bystin. (472 aa)
	HCAG_00829	Uncharacterized protein. (904 aa)
	HCAG_07125	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (334 aa)
	HCAG_05902	Uncharacterized protein. (2307 aa)
	HCAG_03777	Bms1-type G domain-containing protein. (768 aa)
	HCAG_00604	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (439 aa)
	HCAG_03776	WD_REPEATS_REGION domain-containing protein. (545 aa)
	HCAG_03642	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (142 aa)
	HCAG_02665	RIO domain-containing protein. (279 aa)
	HCAG_00214	KH type-2 domain-containing protein. (239 aa)
	HCAG_02827	CBF domain-containing protein. (428 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00214	HCAG_00604	A6QS58	A6QT98	KH type-2 domain-containing protein.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.845
HCAG_00214	HCAG_00829	A6QS58	A6QTX3	KH type-2 domain-containing protein.	Uncharacterized protein.	0.940
HCAG_00214	HCAG_02665	A6QS58	A6QZ58	KH type-2 domain-containing protein.	RIO domain-containing protein.	0.989
HCAG_00214	HCAG_03642	A6QS58	A6R1Y4	KH type-2 domain-containing protein.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.838
HCAG_00214	HCAG_03777	A6QS58	A6R2B9	KH type-2 domain-containing protein.	Bms1-type G domain-containing protein.	0.927
HCAG_00214	HCAG_07125	A6QS58	A6RBW7	KH type-2 domain-containing protein.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.943
HCAG_00214	HCAG_07626	A6QS58	A6RDB8	KH type-2 domain-containing protein.	Bystin.	0.997
HCAG_00214	HCAG_09041	A6QS58	A6RHC4	KH type-2 domain-containing protein.	Uncharacterized protein.	0.992
HCAG_00604	HCAG_00214	A6QT98	A6QS58	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	KH type-2 domain-containing protein.	0.845
HCAG_00604	HCAG_00829	A6QT98	A6QTX3	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Uncharacterized protein.	0.808
HCAG_00604	HCAG_01798	A6QT98	A6QWP1	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Uncharacterized protein.	0.757
HCAG_00604	HCAG_02665	A6QT98	A6QZ58	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	RIO domain-containing protein.	0.999
HCAG_00604	HCAG_02827	A6QT98	A6QZM0	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	CBF domain-containing protein.	0.866
HCAG_00604	HCAG_03642	A6QT98	A6R1Y4	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.924
HCAG_00604	HCAG_03776	A6QT98	A6R2B8	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	WD_REPEATS_REGION domain-containing protein.	0.799
HCAG_00604	HCAG_03777	A6QT98	A6R2B9	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Bms1-type G domain-containing protein.	0.999
HCAG_00604	HCAG_07125	A6QT98	A6RBW7	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.870
HCAG_00604	HCAG_07626	A6QT98	A6RDB8	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Bystin.	0.999
HCAG_00604	HCAG_09041	A6QT98	A6RHC4	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	Uncharacterized protein.	0.999
HCAG_00829	HCAG_00214	A6QTX3	A6QS58	Uncharacterized protein.	KH type-2 domain-containing protein.	0.940