(24 nodes) ncRNA catabolic process network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_04572	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (417 aa)
	HCAG_05387	KH_dom_type_1 domain-containing protein. (279 aa)
	HCAG_05461	HRDC domain-containing protein. (807 aa)
	HCAG_05592	ATP-dependent RNA helicase DOB1. (1081 aa)
	HCAG_06423	Sec2p domain-containing protein. (252 aa)
	HCAG_06696	CCHC-type domain-containing protein. (475 aa)
	HCAG_06697	Uncharacterized protein. (232 aa)
	HCAG_06875	RAI1 domain-containing protein. (396 aa)
	HCAG_05940	RNase_PH domain-containing protein. (337 aa)
	HCAG_06137	Mitotic control protein dis3. (236 aa)
	HCAG_06138	Mitotic control protein dis3. (459 aa)
	HCAG_07044	Uncharacterized protein. (657 aa)
	HCAG_07214	Uncharacterized protein. (252 aa)
	HCAG_07682	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	HCAG_08104	Uncharacterized protein. (673 aa)
	HCAG_06016	Uncharacterized protein. (1261 aa)
	HCAG_00485	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1327 aa)
	HCAG_01190	Uncharacterized protein. (249 aa)
	HCAG_02080	Uncharacterized protein. (361 aa)
	HCAG_02509	Uncharacterized protein. (289 aa)
	HCAG_03200	RNase_PH domain-containing protein. (440 aa)
	HCAG_03457	ECR1_N domain-containing protein. (372 aa)
	HCAG_04052	Uncharacterized protein. (430 aa)
	HCAG_04484	RNase_PH domain-containing protein. (291 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00485	HCAG_02509	A6QSX9	A6QYQ2	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Uncharacterized protein.	0.693
HCAG_00485	HCAG_03200	A6QSX9	A6R0P3	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	RNase_PH domain-containing protein.	0.711
HCAG_00485	HCAG_03457	A6QSX9	A6R1F0	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	ECR1_N domain-containing protein.	0.685
HCAG_00485	HCAG_04052	A6QSX9	A6R344	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Uncharacterized protein.	0.668
HCAG_00485	HCAG_04484	A6QSX9	A6R4C6	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	RNase_PH domain-containing protein.	0.808
HCAG_00485	HCAG_04572	A6QSX9	A6R4L4	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.552
HCAG_00485	HCAG_05387	A6QSX9	A6R6X9	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	KH_dom_type_1 domain-containing protein.	0.726
HCAG_00485	HCAG_05592	A6QSX9	A6R7I4	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	ATP-dependent RNA helicase DOB1.	0.611
HCAG_00485	HCAG_05940	A6QSX9	A6RAF2	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	RNase_PH domain-containing protein.	0.740
HCAG_00485	HCAG_06137	A6QSX9	A6RAZ9	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Mitotic control protein dis3.	0.728
HCAG_00485	HCAG_06138	A6QSX9	A6RB00	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Mitotic control protein dis3.	0.728
HCAG_00485	HCAG_06423	A6QSX9	A6R7Y2	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Sec2p domain-containing protein.	0.693
HCAG_00485	HCAG_06696	A6QSX9	A6R8Q5	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	CCHC-type domain-containing protein.	0.660
HCAG_00485	HCAG_06697	A6QSX9	A6R8Q6	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Uncharacterized protein.	0.696
HCAG_00485	HCAG_06875	A6QSX9	A6R984	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	RAI1 domain-containing protein.	0.515
HCAG_00485	HCAG_07044	A6QSX9	A6RBN6	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Uncharacterized protein.	0.409
HCAG_00485	HCAG_07214	A6QSX9	A6RC56	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Uncharacterized protein.	0.822
HCAG_01190	HCAG_02509	A6QUY4	A6QYQ2	Uncharacterized protein.	Uncharacterized protein.	0.992
HCAG_01190	HCAG_03200	A6QUY4	A6R0P3	Uncharacterized protein.	RNase_PH domain-containing protein.	0.997
HCAG_01190	HCAG_03457	A6QUY4	A6R1F0	Uncharacterized protein.	ECR1_N domain-containing protein.	0.997