(62 nodes) Sporulation network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_01271	PIPK domain-containing protein. (781 aa)
	HCAG_01087	RRM domain-containing protein. (314 aa)
	HCAG_00894	Protein ras-1. (149 aa)
	HCAG_00852	Serine/threonine-protein kinase nrc-2. (584 aa)
	HCAG_00807	Serine/threonine-protein phosphatase. (213 aa)
	HCAG_00784	Uncharacterized protein. (482 aa)
	HCAG_00742	Guanine nucleotide-binding protein alpha subunit. (353 aa)
	HCAG_00634	Uncharacterized protein. (640 aa)
	HCAG_00594	Hydrophobin. (137 aa)
	HCAG_00166	F-box domain-containing protein. (551 aa)
	HCAG_00009	Uncharacterized protein. (270 aa)
	HCAG_09223	RRM domain-containing protein. (466 aa)
	HCAG_08883	Chitin synthase; Plays a major role in cell wall biogenesis. (912 aa)
	HCAG_08842	Chitin synthase; Plays a major role in cell wall biogenesis. (916 aa)
	HCAG_08780	Uncharacterized protein. (187 aa)
	HCAG_08618	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	HCAG_08430	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
	HCAG_08288	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	HCAG_08008	Chitin synthase 2. (1277 aa)
	HCAG_07838	Uncharacterized protein. (685 aa)
	HCAG_07413	Uncharacterized protein. (508 aa)
	HCAG_07260	Developmental protein FluG; Belongs to the glutamine synthetase family. (877 aa)
	HCAG_07119	Uncharacterized protein. (163 aa)
	HCAG_06302	Uncharacterized protein. (161 aa)
	HCAG_06004	Uncharacterized protein. (577 aa)
	HCAG_05911	Uncharacterized protein. (281 aa)
	HCAG_05786	BZIP domain-containing protein. (520 aa)
	HCAG_06891	Uncharacterized protein. (639 aa)
	HCAG_06889	Transcriptional repressor TUP1. (568 aa)
	HCAG_06674	Conidiophore development protein hymA. (395 aa)
	HCAG_06609	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1266 aa)
	HCAG_06491	Phospholipase. (1029 aa)
	HCAG_06403	Uncharacterized protein. (342 aa)
	HCAG_05537	Uncharacterized protein. (902 aa)
	HCAG_05469	KH_dom_type_1 domain-containing protein. (769 aa)
	HCAG_05465	CRAL-TRIO domain-containing protein. (306 aa)
	HCAG_05369	Uncharacterized protein. (142 aa)
	HCAG_05268	Trehalose-6-phosphate synthase. (518 aa)
	HCAG_05193	Uncharacterized protein. (325 aa)
	HCAG_05075	Uncharacterized protein. (329 aa)
	HCAG_04841	Serine/threonine-protein phosphatase. (253 aa)
	HCAG_04824	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (94 aa)
	HCAG_04754	Uncharacterized protein. (170 aa)
	HCAG_04230	Uncharacterized protein. (198 aa)
	HCAG_04186	TUG-UBL1 domain-containing protein. (485 aa)
	HCAG_03903	Sad1-interacting factor 2. (536 aa)
	HCAG_03725	Protein dopey. (1788 aa)
	HCAG_03502	Phospholipase. (1251 aa)
	HCAG_03289	Velvet domain-containing protein. (373 aa)
	HCAG_02940	PH domain-containing protein. (1556 aa)
	HCAG_02857	Chitin synthase D. (1220 aa)
	HCAG_02588	Uncharacterized protein. (569 aa)
	HCAG_02472	TIP120 domain-containing protein. (1193 aa)
	HCAG_02368	Uncharacterized protein. (225 aa)
	HCAG_02202	Uncharacterized protein. (445 aa)
	HCAG_02190	Uncharacterized protein. (325 aa)
	HCAG_02006	Cell division control protein 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (344 aa)
	HCAG_01774	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1400 aa)
	HCAG_01708	Velvet domain-containing protein. (588 aa)
	HCAG_01552	Mannose-1-phosphate guanyltransferase. (364 aa)
	HCAG_01379	Uncharacterized protein. (466 aa)
	HCAG_01188	UBX domain-containing protein. (458 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00166	HCAG_02472	A6QS10	A6QYL5	F-box domain-containing protein.	TIP120 domain-containing protein.	0.719
HCAG_00742	HCAG_00894	A6QTN6	A6QU38	Guanine nucleotide-binding protein alpha subunit.	Protein ras-1.	0.421
HCAG_00742	HCAG_07838	A6QTN6	A6RDY0	Guanine nucleotide-binding protein alpha subunit.	Uncharacterized protein.	0.944
HCAG_00807	HCAG_04841	A6QTV1	A6R5D3	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.911
HCAG_00807	HCAG_08288	A6QTV1	A6RF72	Serine/threonine-protein phosphatase.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.595
HCAG_00807	HCAG_08430	A6QTV1	A6RFL4	Serine/threonine-protein phosphatase.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.400
HCAG_00852	HCAG_08618	A6QTZ6	A6RG52	Serine/threonine-protein kinase nrc-2.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.464
HCAG_00894	HCAG_00742	A6QU38	A6QTN6	Protein ras-1.	Guanine nucleotide-binding protein alpha subunit.	0.421
HCAG_01188	HCAG_04186	A6QUY2	A6R3H8	UBX domain-containing protein.	TUG-UBL1 domain-containing protein.	0.484
HCAG_01708	HCAG_02202	A6QWF1	A6QXU5	Velvet domain-containing protein.	Uncharacterized protein.	0.621
HCAG_01708	HCAG_02368	A6QWF1	A6QYB1	Velvet domain-containing protein.	Uncharacterized protein.	0.622
HCAG_01708	HCAG_03289	A6QWF1	A6R0Y2	Velvet domain-containing protein.	Velvet domain-containing protein.	0.678
HCAG_01708	HCAG_07413	A6QWF1	A6RCQ5	Velvet domain-containing protein.	Uncharacterized protein.	0.539
HCAG_02202	HCAG_01708	A6QXU5	A6QWF1	Uncharacterized protein.	Velvet domain-containing protein.	0.621
HCAG_02202	HCAG_02368	A6QXU5	A6QYB1	Uncharacterized protein.	Uncharacterized protein.	0.624
HCAG_02202	HCAG_03289	A6QXU5	A6R0Y2	Uncharacterized protein.	Velvet domain-containing protein.	0.445
HCAG_02202	HCAG_07260	A6QXU5	A6RCA2	Uncharacterized protein.	Developmental protein FluG; Belongs to the glutamine synthetase family.	0.461
HCAG_02202	HCAG_07413	A6QXU5	A6RCQ5	Uncharacterized protein.	Uncharacterized protein.	0.634
HCAG_02202	HCAG_07838	A6QXU5	A6RDY0	Uncharacterized protein.	Uncharacterized protein.	0.475
HCAG_02368	HCAG_01708	A6QYB1	A6QWF1	Uncharacterized protein.	Velvet domain-containing protein.	0.622