STRINGSTRING
HCAG_03174 HCAG_03174 HCAG_02733 HCAG_02733 HCAG_00171 HCAG_00171 HCAG_08430 HCAG_08430 HCAG_06165 HCAG_06165 HCAG_06164 HCAG_06164 HCAG_06686 HCAG_06686 HCAG_06610 HCAG_06610 HCAG_05293 HCAG_05293 HCAG_04901 HCAG_04901 HCAG_04752 HCAG_04752 HCAG_04706 HCAG_04706 HCAG_00848 HCAG_00848 HCAG_04115 HCAG_04115 HCAG_03175 HCAG_03175
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCAG_03174Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (174 aa)
HCAG_02733Uncharacterized protein. (689 aa)
HCAG_00171Protein kinase domain-containing protein. (821 aa)
HCAG_08430Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
HCAG_06165Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (759 aa)
HCAG_06164Uncharacterized protein. (166 aa)
HCAG_06686MHD domain-containing protein. (858 aa)
HCAG_06610Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
HCAG_05293DUF2013 domain-containing protein. (749 aa)
HCAG_04901Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
HCAG_04752F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
HCAG_04706Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (318 aa)
HCAG_00848Arp2/3 complex subunit; Belongs to the actin family. (439 aa)
HCAG_04115Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (369 aa)
HCAG_03175Uncharacterized protein. (790 aa)
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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