(28 nodes) Late endosome to vacuole transport network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_08213	Sld7_C domain-containing protein. (594 aa)
	HCAG_08212	Uncharacterized protein. (173 aa)
	HCAG_08016	GLUE N-terminal domain-containing protein. (646 aa)
	HCAG_07627	Uncharacterized protein. (209 aa)
	HCAG_06159	E3 ubiquitin-protein ligase. (883 aa)
	HCAG_06132	Uncharacterized protein. (236 aa)
	HCAG_06719	Uncharacterized protein. (412 aa)
	HCAG_06510	Uncharacterized protein. (495 aa)
	HCAG_05521	Uncharacterized protein. (646 aa)
	HCAG_05491	Uncharacterized protein. (223 aa)
	HCAG_05411	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family. (353 aa)
	HCAG_04796	Vta1 domain-containing protein. (279 aa)
	HCAG_00967	Uncharacterized protein. (259 aa)
	HCAG_01068	WD_REPEATS_REGION domain-containing protein. (1298 aa)
	HCAG_01546	Uncharacterized protein. (866 aa)
	HCAG_01547	Uncharacterized protein. (1700 aa)
	HCAG_01600	Uncharacterized protein. (354 aa)
	HCAG_01966	Uncharacterized protein. (211 aa)
	HCAG_02174	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (238 aa)
	HCAG_02484	Uncharacterized protein. (228 aa)
	HCAG_02495	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (755 aa)
	HCAG_04350	MPN domain-containing protein. (519 aa)
	HCAG_08804	Uncharacterized protein. (892 aa)
	HCAG_08724	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (846 aa)
	HCAG_08705	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (266 aa)
	HCAG_08438	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (296 aa)
	HCAG_08344	Uncharacterized protein. (227 aa)
	HCAG_08214	Uncharacterized protein. (128 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01546	HCAG_01547	A6QVY9	A6QVZ0	Uncharacterized protein.	Uncharacterized protein.	0.945
HCAG_01547	HCAG_01546	A6QVZ0	A6QVY9	Uncharacterized protein.	Uncharacterized protein.	0.945
HCAG_01600	HCAG_01966	A6QW43	A6QX59	Uncharacterized protein.	Uncharacterized protein.	0.862
HCAG_01600	HCAG_02174	A6QW43	A6QXR7	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.630
HCAG_01600	HCAG_02484	A6QW43	A6QYM7	Uncharacterized protein.	Uncharacterized protein.	0.965
HCAG_01600	HCAG_04796	A6QW43	A6R588	Uncharacterized protein.	Vta1 domain-containing protein.	0.998
HCAG_01600	HCAG_05411	A6QW43	A6R703	Uncharacterized protein.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.990
HCAG_01600	HCAG_05491	A6QW43	A6R783	Uncharacterized protein.	Uncharacterized protein.	0.978
HCAG_01600	HCAG_06132	A6QW43	A6RAZ4	Uncharacterized protein.	Uncharacterized protein.	0.608
HCAG_01600	HCAG_06510	A6QW43	A6R869	Uncharacterized protein.	Uncharacterized protein.	0.803
HCAG_01600	HCAG_06719	A6QW43	A6R8S8	Uncharacterized protein.	Uncharacterized protein.	0.946
HCAG_01600	HCAG_07627	A6QW43	A6RDB9	Uncharacterized protein.	Uncharacterized protein.	0.948
HCAG_01600	HCAG_08016	A6QW43	A6REF1	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.608
HCAG_01600	HCAG_08344	A6QW43	A6RFC8	Uncharacterized protein.	Uncharacterized protein.	0.935
HCAG_01966	HCAG_01600	A6QX59	A6QW43	Uncharacterized protein.	Uncharacterized protein.	0.862
HCAG_01966	HCAG_02174	A6QX59	A6QXR7	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.896
HCAG_01966	HCAG_02484	A6QX59	A6QYM7	Uncharacterized protein.	Uncharacterized protein.	0.986
HCAG_01966	HCAG_04796	A6QX59	A6R588	Uncharacterized protein.	Vta1 domain-containing protein.	0.830
HCAG_01966	HCAG_05411	A6QX59	A6R703	Uncharacterized protein.	Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family.	0.994
HCAG_01966	HCAG_05491	A6QX59	A6R783	Uncharacterized protein.	Uncharacterized protein.	0.995