(52 nodes) Regulation of transport network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06949	Protein kinase domain-containing protein. (401 aa)
	HCAG_08974	Nonspecific lipid-transfer protein, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (458 aa)
	HCAG_08934	Uncharacterized protein. (120 aa)
	HCAG_08839	Protein kinase domain-containing protein. (389 aa)
	HCAG_08773	WD_REPEATS_REGION domain-containing protein. (723 aa)
	HCAG_07652	Uncharacterized protein. (158 aa)
	HCAG_07536	Protein kinase dsk1. (567 aa)
	HCAG_07424	Mcp5_PH domain-containing protein. (750 aa)
	HCAG_07423	Uncharacterized protein. (509 aa)
	HCAG_07094	Protein kinase domain-containing protein. (268 aa)
	HCAG_07076	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (598 aa)
	HCAG_06189	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (423 aa)
	HCAG_06167	Protein kinase domain-containing protein. (1110 aa)
	HCAG_06130	Protein kinase domain-containing protein. (369 aa)
	HCAG_06584	Uncharacterized protein. (804 aa)
	HCAG_06486	RHOMBOID-like protein. (548 aa)
	HCAG_06459	Uncharacterized protein. (147 aa)
	HCAG_04944	Uncharacterized protein. (116 aa)
	HCAG_04841	Serine/threonine-protein phosphatase. (253 aa)
	HCAG_04840	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
	HCAG_04683	Uncharacterized protein. (566 aa)
	HCAG_04452	Fungal_trans domain-containing protein. (445 aa)
	HCAG_04439	Uncharacterized protein. (520 aa)
	HCAG_04377	Uncharacterized protein. (214 aa)
	HCAG_04331	Uncharacterized protein. (332 aa)
	HCAG_04210	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
	HCAG_04189	Protein kinase domain-containing protein. (117 aa)
	HCAG_04134	Protein kinase domain-containing protein. (273 aa)
	HCAG_03980	Protein kinase domain-containing protein. (374 aa)
	HCAG_03898	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4863 aa)
	HCAG_03869	Uncharacterized protein. (389 aa)
	HCAG_03617	Uncharacterized protein. (930 aa)
	HCAG_03439	TMF_TATA_bd domain-containing protein. (864 aa)
	HCAG_03361	Uncharacterized protein. (604 aa)
	HCAG_02815	Uncharacterized protein. (182 aa)
	HCAG_02665	RIO domain-containing protein. (279 aa)
	HCAG_02233	SAC domain-containing protein. (707 aa)
	HCAG_02232	Uncharacterized protein. (140 aa)
	HCAG_01929	Protein kinase domain-containing protein. (300 aa)
	HCAG_01630	Uncharacterized protein. (385 aa)
	HCAG_01579	Zn(2)-C6 fungal-type domain-containing protein. (620 aa)
	HCAG_01501	Serine/threonine-protein kinase cot-1. (639 aa)
	HCAG_01376	Ubiquitin carboxyl-terminal hydrolase. (643 aa)
	HCAG_01328	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
	HCAG_01294	Uncharacterized protein. (747 aa)
	HCAG_01241	Protein Rho3. (206 aa)
	HCAG_00959	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (102 aa)
	HCAG_00958	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (426 aa)
	HCAG_00807	Serine/threonine-protein phosphatase. (213 aa)
	HCAG_00679	DUF1752 domain-containing protein. (518 aa)
	HCAG_00472	AMP-binding domain-containing protein. (658 aa)
	HCAG_00402	Protein kinase domain-containing protein. (348 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00472	HCAG_01294	A6QSW6	A6QV87	AMP-binding domain-containing protein.	Uncharacterized protein.	0.909
HCAG_00679	HCAG_03361	A6QTH3	A6R154	DUF1752 domain-containing protein.	Uncharacterized protein.	0.567
HCAG_00807	HCAG_01241	A6QTV1	A6QV34	Serine/threonine-protein phosphatase.	Protein Rho3.	0.528
HCAG_00807	HCAG_04841	A6QTV1	A6R5D3	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.911
HCAG_00807	HCAG_06167	A6QTV1	A6RB29	Serine/threonine-protein phosphatase.	Protein kinase domain-containing protein.	0.708
HCAG_00958	HCAG_00959	A6QUA2	A6QUA3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.896
HCAG_00959	HCAG_00958	A6QUA3	A6QUA2	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.896
HCAG_01241	HCAG_00807	A6QV34	A6QTV1	Protein Rho3.	Serine/threonine-protein phosphatase.	0.528
HCAG_01241	HCAG_06189	A6QV34	A6RB51	Protein Rho3.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
HCAG_01241	HCAG_08773	A6QV34	A6RGK6	Protein Rho3.	WD_REPEATS_REGION domain-containing protein.	0.455
HCAG_01294	HCAG_00472	A6QV87	A6QSW6	Uncharacterized protein.	AMP-binding domain-containing protein.	0.909
HCAG_01376	HCAG_04683	A6QVG9	A6R4X5	Ubiquitin carboxyl-terminal hydrolase.	Uncharacterized protein.	0.994
HCAG_01501	HCAG_06167	A6QVU4	A6RB29	Serine/threonine-protein kinase cot-1.	Protein kinase domain-containing protein.	0.565
HCAG_01929	HCAG_04189	A6QX22	A6R3I1	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.445
HCAG_02232	HCAG_02233	A6QXX5	A6QXX6	Uncharacterized protein.	SAC domain-containing protein.	0.899
HCAG_02233	HCAG_02232	A6QXX6	A6QXX5	SAC domain-containing protein.	Uncharacterized protein.	0.899
HCAG_02665	HCAG_07076	A6QZ58	A6RBR8	RIO domain-containing protein.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.705
HCAG_03361	HCAG_00679	A6R154	A6QTH3	Uncharacterized protein.	DUF1752 domain-containing protein.	0.567
HCAG_03361	HCAG_03869	A6R154	A6R2L1	Uncharacterized protein.	Uncharacterized protein.	0.567
HCAG_03361	HCAG_07423	A6R154	A6RCR5	Uncharacterized protein.	Uncharacterized protein.	0.567