(66 nodes) Cell tip network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_09038	Uncharacterized protein. (1181 aa)
	HCAG_00012	Uncharacterized protein. (979 aa)
	HCAG_00216	Protein phosphatase PP2A regulatory subunit A. (613 aa)
	HCAG_00245	Uncharacterized protein. (1168 aa)
	HCAG_00344	IPPc domain-containing protein. (1181 aa)
	HCAG_00599	Uncharacterized protein. (242 aa)
	HCAG_00716	CNH domain-containing protein. (105 aa)
	HCAG_00731	Uncharacterized protein. (167 aa)
	HCAG_00771	Adenylyl cyclase-associated protein; Belongs to the CAP family. (500 aa)
	HCAG_00848	Arp2/3 complex subunit; Belongs to the actin family. (439 aa)
	HCAG_01091	Uncharacterized protein. (2668 aa)
	HCAG_01146	Uncharacterized protein. (412 aa)
	HCAG_01195	Sec2p domain-containing protein. (651 aa)
	HCAG_01300	SH3 domain-containing protein. (787 aa)
	HCAG_01316	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1616 aa)
	HCAG_01325	Calmodulin; Belongs to the calmodulin family. (149 aa)
	HCAG_01357	Uncharacterized protein. (326 aa)
	HCAG_01501	Serine/threonine-protein kinase cot-1. (639 aa)
	HCAG_01561	Uncharacterized protein. (929 aa)
	HCAG_01565	Uds1 domain-containing protein. (807 aa)
	HCAG_01599	Drf_GBD domain-containing protein. (827 aa)
	PRM1	Plasma membrane fusion protein PRM1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family. (736 aa)
	HCAG_01735	Uncharacterized protein. (186 aa)
	HCAG_02126	Uncharacterized protein. (433 aa)
	HCAG_02424	DUF4045 domain-containing protein. (911 aa)
	HCAG_02615	Uncharacterized protein. (417 aa)
	HCAG_02657	Dynein heavy chain. (1199 aa)
	HCAG_02658	Dynein heavy chain. (2811 aa)
	HCAG_02742	Uncharacterized protein. (190 aa)
	HCAG_02752	CAP-Gly domain-containing protein. (747 aa)
	HCAG_03003	T5orf172 domain-containing protein. (469 aa)
	HCAG_03019	Non-specific serine/threonine protein kinase. (881 aa)
	HCAG_03218	Uncharacterized protein. (608 aa)
	HCAG_03461	Protein kinase byr1. (541 aa)
	HCAG_03506	Uncharacterized protein. (759 aa)
	HCAG_03603	RING-type domain-containing protein. (562 aa)
	HCAG_03718	Uncharacterized protein. (988 aa)
	HCAG_03719	Uncharacterized protein. (531 aa)
	HCAG_03747	Uncharacterized protein. (503 aa)
	HCAG_04015	Coronin; Belongs to the WD repeat coronin family. (485 aa)
	HCAG_04097	Uncharacterized protein. (1689 aa)
	HCAG_04486	Uncharacterized protein. (235 aa)
	HCAG_04487	Uncharacterized protein. (419 aa)
	HCAG_04652	Uncharacterized protein. (1410 aa)
	HCAG_04752	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
	HCAG_05365	Uncharacterized protein. (1414 aa)
	HCAG_05464	Ras-GAP domain-containing protein. (424 aa)
	HCAG_05579	Uncharacterized protein. (446 aa)
	HCAG_06352	DH domain-containing protein. (1976 aa)
	HCAG_06471	Uncharacterized protein. (671 aa)
	HCAG_06674	Conidiophore development protein hymA. (395 aa)
	HCAG_06848	Cytokinesis protein sepA. (1670 aa)
	HCAG_05994	Dynactin domain-containing protein. (1217 aa)
	HCAG_06042	Sec3_C domain-containing protein. (273 aa)
	HCAG_06043	Sec3-PIP2_bind domain-containing protein. (1070 aa)
	HCAG_06143	AIP3 domain-containing protein. (1021 aa)
	HCAG_07050	TRP domain-containing protein. (412 aa)
	HCAG_07051	TRP domain-containing protein. (196 aa)
	HCAG_07207	Uncharacterized protein. (641 aa)
	HCAG_08014	Uncharacterized protein. (610 aa)
	HCAG_08090	SH3 domain-containing protein. (1196 aa)
	HCAG_09343	CNH domain-containing protein. (175 aa)
	HCAG_08480	Tubulin gamma chain; Belongs to the tubulin family. (655 aa)
	HCAG_08699	Usp domain-containing protein. (459 aa)
	HCAG_08842	Chitin synthase; Plays a major role in cell wall biogenesis. (916 aa)
	HCAG_09016	Non-specific serine/threonine protein kinase. (904 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00216	HCAG_00245	A6QS60	A6QS89	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.446
HCAG_00216	HCAG_03218	A6QS60	A6R0R1	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.446
HCAG_00245	HCAG_00216	A6QS89	A6QS60	Uncharacterized protein.	Protein phosphatase PP2A regulatory subunit A.	0.446
HCAG_00245	HCAG_00716	A6QS89	A6QTL0	Uncharacterized protein.	CNH domain-containing protein.	0.701
HCAG_00245	HCAG_00848	A6QS89	A6QTZ2	Uncharacterized protein.	Arp2/3 complex subunit; Belongs to the actin family.	0.458
HCAG_00245	HCAG_04097	A6QS89	A6R389	Uncharacterized protein.	Uncharacterized protein.	0.445
HCAG_00245	HCAG_09343	A6QS89	A6XPM0	Uncharacterized protein.	CNH domain-containing protein.	0.701
HCAG_00599	HCAG_01146	A6QT93	A6QUU0	Uncharacterized protein.	Uncharacterized protein.	0.478
HCAG_00599	HCAG_01561	A6QT93	A6QW04	Uncharacterized protein.	Uncharacterized protein.	0.441
HCAG_00599	HCAG_08014	A6QT93	A6REE9	Uncharacterized protein.	Uncharacterized protein.	0.660
HCAG_00716	HCAG_00245	A6QTL0	A6QS89	CNH domain-containing protein.	Uncharacterized protein.	0.701
HCAG_00716	HCAG_03218	A6QTL0	A6R0R1	CNH domain-containing protein.	Uncharacterized protein.	0.701
HCAG_00771	HCAG_00848	A6QTR5	A6QTZ2	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Arp2/3 complex subunit; Belongs to the actin family.	0.659
HCAG_00771	HCAG_04752	A6QTR5	A6R544	Adenylyl cyclase-associated protein; Belongs to the CAP family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.559
HCAG_00848	HCAG_00245	A6QTZ2	A6QS89	Arp2/3 complex subunit; Belongs to the actin family.	Uncharacterized protein.	0.458
HCAG_00848	HCAG_00771	A6QTZ2	A6QTR5	Arp2/3 complex subunit; Belongs to the actin family.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.659
HCAG_00848	HCAG_01325	A6QTZ2	A6QVB8	Arp2/3 complex subunit; Belongs to the actin family.	Calmodulin; Belongs to the calmodulin family.	0.561
HCAG_00848	HCAG_02424	A6QTZ2	A6QYG7	Arp2/3 complex subunit; Belongs to the actin family.	DUF4045 domain-containing protein.	0.408
HCAG_00848	HCAG_02657	A6QTZ2	A6QZ50	Arp2/3 complex subunit; Belongs to the actin family.	Dynein heavy chain.	0.402
HCAG_00848	HCAG_02658	A6QTZ2	A6QZ51	Arp2/3 complex subunit; Belongs to the actin family.	Dynein heavy chain.	0.402