(7 nodes) Misfolded protein binding network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05385	Uncharacterized protein; Belongs to the heat shock protein 70 family. (504 aa)
	HCAG_09066	J domain-containing protein. (323 aa)
	HCAG_08176	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family. (676 aa)
	HCAG_05805	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family. (677 aa)
	HCAG_06824	ClpB_D2-small domain-containing protein. (355 aa)
	HCAG_05170	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (273 aa)
	HCAG_03048	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (280 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_03048	HCAG_05170	A6R091	A6R6B2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.995
HCAG_03048	HCAG_05805	A6R091	A6RA17	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.962
HCAG_05170	HCAG_03048	A6R6B2	A6R091	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.995
HCAG_05170	HCAG_05805	A6R6B2	A6RA17	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.858
HCAG_05385	HCAG_05805	A6R6X7	A6RA17	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.780
HCAG_05385	HCAG_06824	A6R6X7	A6R933	Uncharacterized protein; Belongs to the heat shock protein 70 family.	ClpB_D2-small domain-containing protein.	0.699
HCAG_05385	HCAG_08176	A6R6X7	A6REW1	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family.	0.665
HCAG_05385	HCAG_09066	A6R6X7	A6RHE9	Uncharacterized protein; Belongs to the heat shock protein 70 family.	J domain-containing protein.	0.635
HCAG_05805	HCAG_03048	A6RA17	A6R091	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.962
HCAG_05805	HCAG_05170	A6RA17	A6R6B2	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.858
HCAG_05805	HCAG_05385	A6RA17	A6R6X7	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.780
HCAG_05805	HCAG_06824	A6RA17	A6R933	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	ClpB_D2-small domain-containing protein.	0.618
HCAG_05805	HCAG_08176	A6RA17	A6REW1	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family.	0.779
HCAG_05805	HCAG_09066	A6RA17	A6RHE9	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	J domain-containing protein.	0.847
HCAG_06824	HCAG_05385	A6R933	A6R6X7	ClpB_D2-small domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.699
HCAG_06824	HCAG_05805	A6R933	A6RA17	ClpB_D2-small domain-containing protein.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.618
HCAG_06824	HCAG_08176	A6R933	A6REW1	ClpB_D2-small domain-containing protein.	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family.	0.678
HCAG_06824	HCAG_09066	A6R933	A6RHE9	ClpB_D2-small domain-containing protein.	J domain-containing protein.	0.442
HCAG_08176	HCAG_05385	A6REW1	A6R6X7	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.665
HCAG_08176	HCAG_05805	A6REW1	A6RA17	Heat shock protein SSC1, mitochondrial; Belongs to the heat shock protein 70 family.	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.	0.779