(54 nodes) Transition metal ion homeostasis network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_00727	Uncharacterized protein. (255 aa)
	HCAG_00065	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (328 aa)
	HCAG_09185	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (203 aa)
	HCAG_08685	Uncharacterized protein. (596 aa)
	HCAG_08622	Uncharacterized protein. (906 aa)
	HCAG_08369	Uncharacterized protein. (206 aa)
	HCAG_08321	Uncharacterized protein. (589 aa)
	HCAG_08316	Uncharacterized protein. (1206 aa)
	HCAG_08291	Uncharacterized protein. (278 aa)
	HCAG_07910	Uncharacterized protein. (363 aa)
	HCAG_07816	Uncharacterized protein. (500 aa)
	HCAG_07754	Uncharacterized protein. (108 aa)
	HCAG_07723	Uncharacterized protein. (107 aa)
	HCAG_07429	Carrier domain-containing protein. (628 aa)
	HCAG_07428	Uncharacterized protein. (1645 aa)
	HCAG_07381	FAD-binding FR-type domain-containing protein. (361 aa)
	HCAG_07324	Uncharacterized protein. (407 aa)
	HCAG_07290	Siderophore iron transporter mirC. (532 aa)
	HCAG_07025	Uncharacterized protein. (193 aa)
	HCAG_06107	Uncharacterized protein. (228 aa)
	HCAG_06076	Uncharacterized protein. (797 aa)
	HCAG_05866	Uncharacterized protein. (586 aa)
	HCAG_05676	Copper-fist domain-containing protein. (482 aa)
	HCAG_06636	Uncharacterized protein. (1243 aa)
	HCAG_06462	Uncharacterized protein. (320 aa)
	HCAG_06424	Uncharacterized protein. (421 aa)
	HCAG_05485	Uncharacterized protein. (157 aa)
	HCAG_05344	FAD-binding FR-type domain-containing protein. (326 aa)
	HCAG_05279	Uncharacterized protein; Belongs to the BolA/IbaG family. (94 aa)
	HCAG_05259	Transporter ATM1, mitochondrial. (747 aa)
	HCAG_05045	FAD-binding FR-type domain-containing protein. (717 aa)
	HCAG_05044	Uncharacterized protein. (191 aa)
	HCAG_04992	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
	HCAG_04991	Uncharacterized protein. (631 aa)
	HCAG_04678	Uncharacterized protein. (365 aa)
	HCAG_04667	Myb-like domain-containing protein. (206 aa)
	HCAG_04365	Sulfhydryl oxidase. (158 aa)
	HCAG_04275	Uncharacterized protein. (154 aa)
	HCAG_04257	Zinc homeostasis factor 1. (525 aa)
	HCAG_04254	DUF202 domain-containing protein. (402 aa)
	HCAG_03906	Uncharacterized protein. (379 aa)
	HCAG_03430	Uncharacterized protein. (498 aa)
	HCAG_03201	Uncharacterized protein. (763 aa)
	HCAG_03149	FAD-binding FR-type domain-containing protein. (633 aa)
	HCAG_02735	J domain-containing protein. (279 aa)
	HCAG_02320	FAD-binding FR-type domain-containing protein. (559 aa)
	HCAG_01990	Uncharacterized protein. (507 aa)
	HCAG_01925	FAD-binding FR-type domain-containing protein. (574 aa)
	HCAG_01641	FAD-binding FR-type domain-containing protein. (456 aa)
	HCAG_01056	Uncharacterized protein. (1126 aa)
	HCAG_00946	Uncharacterized protein. (362 aa)
	HCAG_00945	Uncharacterized protein. (341 aa)
	HCAG_00795	Uncharacterized protein. (312 aa)
	HCAG_00117	Uncharacterized protein. (251 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00117	HCAG_05866	A6QRW1	A6RA78	Uncharacterized protein.	Uncharacterized protein.	0.443
HCAG_00117	HCAG_07816	A6QRW1	A6RDV8	Uncharacterized protein.	Uncharacterized protein.	0.448
HCAG_00945	HCAG_00946	A6QU89	A6QU90	Uncharacterized protein.	Uncharacterized protein.	0.900
HCAG_00946	HCAG_00945	A6QU90	A6QU89	Uncharacterized protein.	Uncharacterized protein.	0.900
HCAG_02735	HCAG_05279	A6QZC8	A6R6M1	J domain-containing protein.	Uncharacterized protein; Belongs to the BolA/IbaG family.	0.424
HCAG_02735	HCAG_06107	A6QZC8	A6RAW9	J domain-containing protein.	Uncharacterized protein.	0.847
HCAG_02735	HCAG_08291	A6QZC8	A6RF75	J domain-containing protein.	Uncharacterized protein.	0.525
HCAG_02735	HCAG_09185	A6QZC8	A6RHQ9	J domain-containing protein.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.992
HCAG_03201	HCAG_08369	A6R0P4	A6RFF3	Uncharacterized protein.	Uncharacterized protein.	0.444
HCAG_03906	HCAG_07324	A6R2P8	A6RCG6	Uncharacterized protein.	Uncharacterized protein.	0.616
HCAG_03906	HCAG_08622	A6R2P8	A6RG56	Uncharacterized protein.	Uncharacterized protein.	0.630
HCAG_04254	HCAG_04257	A6R3P6	A6R3P9	DUF202 domain-containing protein.	Zinc homeostasis factor 1.	0.556
HCAG_04254	HCAG_07324	A6R3P6	A6RCG6	DUF202 domain-containing protein.	Uncharacterized protein.	0.413
HCAG_04257	HCAG_04254	A6R3P9	A6R3P6	Zinc homeostasis factor 1.	DUF202 domain-containing protein.	0.556
HCAG_04257	HCAG_07324	A6R3P9	A6RCG6	Zinc homeostasis factor 1.	Uncharacterized protein.	0.413
HCAG_04275	HCAG_05044	A6R3R7	A6R5Y6	Uncharacterized protein.	Uncharacterized protein.	0.470
HCAG_04275	HCAG_05676	A6R3R7	A6R9N8	Uncharacterized protein.	Copper-fist domain-containing protein.	0.519
HCAG_04275	HCAG_08369	A6R3R7	A6RFF3	Uncharacterized protein.	Uncharacterized protein.	0.700
HCAG_04365	HCAG_05259	A6R407	A6R6K1	Sulfhydryl oxidase.	Transporter ATM1, mitochondrial.	0.449
HCAG_04991	HCAG_04992	A6R5T3	A6R5T4	Uncharacterized protein.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.665