node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCAG_00039 | HCAG_00069 | A6QRN3 | A6QRR3 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.999 |
HCAG_00039 | HCAG_04181 | A6QRN3 | A6R3H3 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 0.999 |
HCAG_00039 | HCAG_07682 | A6QRN3 | A6RDH4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.999 |
HCAG_00069 | HCAG_00039 | A6QRR3 | A6QRN3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 0.999 |
HCAG_00069 | HCAG_04181 | A6QRR3 | A6R3H3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 0.999 |
HCAG_00069 | HCAG_07682 | A6QRR3 | A6RDH4 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.999 |
HCAG_01022 | HCAG_07029 | A6QUG6 | A6RBM1 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.418 |
HCAG_01022 | HCAG_07030 | A6QUG6 | A6RBM2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.418 |
HCAG_04181 | HCAG_00039 | A6R3H3 | A6QRN3 | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 0.999 |
HCAG_04181 | HCAG_00069 | A6R3H3 | A6QRR3 | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.999 |
HCAG_04181 | HCAG_07682 | A6R3H3 | A6RDH4 | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 0.999 |
HCAG_04635 | HCAG_07029 | A6R4S7 | A6RBM1 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.526 |
HCAG_04635 | HCAG_07030 | A6R4S7 | A6RBM2 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.526 |
HCAG_07029 | HCAG_01022 | A6RBM1 | A6QUG6 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | 0.418 |
HCAG_07029 | HCAG_04635 | A6RBM1 | A6R4S7 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.526 |
HCAG_07030 | HCAG_01022 | A6RBM2 | A6QUG6 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. | 0.418 |
HCAG_07030 | HCAG_04635 | A6RBM2 | A6R4S7 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.526 |
HCAG_07682 | HCAG_00039 | A6RDH4 | A6QRN3 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. | 0.999 |
HCAG_07682 | HCAG_00069 | A6RDH4 | A6QRR3 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. | 0.999 |
HCAG_07682 | HCAG_04181 | A6RDH4 | A6R3H3 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. | 26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. | 0.999 |