(42 nodes) Catalytic step 2 spliceosome network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_08281	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	HCAG_07796	WD_REPEATS_REGION domain-containing protein. (583 aa)
	HCAG_07757	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1414 aa)
	HCAG_07565	Pre-mRNA splicing factor slt-11. (405 aa)
	HCAG_04904	PPIase cyclophilin-type domain-containing protein. (527 aa)
	HCAG_04919	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (212 aa)
	HCAG_05023	PSP domain-containing protein. (279 aa)
	HCAG_05496	Uncharacterized protein. (219 aa)
	HCAG_06536	Pinin_SDK_memA domain-containing protein. (354 aa)
	HCAG_06918	PSP domain-containing protein. (574 aa)
	HCAG_07308	Uncharacterized protein. (222 aa)
	HCAG_00426	Uncharacterized protein. (277 aa)
	HCAG_00458	WD_REPEATS_REGION domain-containing protein. (348 aa)
	HCAG_00813	116 kDa U5 small nuclear ribonucleoprotein component. (899 aa)
	HCAG_01049	Sm domain-containing protein. (80 aa)
	HCAG_01196	Uncharacterized protein. (457 aa)
	HCAG_01349	Uncharacterized protein. (295 aa)
	HCAG_01502	Matrin-type domain-containing protein. (260 aa)
	HCAG_02332	Sm domain-containing protein. (171 aa)
	HCAG_02553	Small nuclear ribonucleoprotein Sm D2. (103 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	HCAG_02641	Pre-mRNA splicing factor syf-1. (831 aa)
	HCAG_02780	Small nuclear ribonucleoprotein G. (78 aa)
	HCAG_02845	Uncharacterized protein. (219 aa)
	HCAG_03029	Uncharacterized protein. (530 aa)
	HCAG_03195	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (148 aa)
	HCAG_03306	Peptidyl-prolyl cis-trans isomerase cypE. (629 aa)
	HCAG_03365	Uncharacterized protein. (88 aa)
	HCAG_03437	Pre-mRNA splicing factor prp46. (458 aa)
	HCAG_03604	Uncharacterized protein. (285 aa)
	HCAG_03643	Pre-mRNA splicing factor prp1. (918 aa)
	HCAG_03657	RRM domain-containing protein. (115 aa)
	HCAG_03763	RRM domain-containing protein. (154 aa)
	HCAG_04232	Sm domain-containing protein. (244 aa)
	HCAG_04402	WD_REPEATS_REGION domain-containing protein. (360 aa)
	HCAG_04440	Uncharacterized protein. (263 aa)
	HCAG_04558	Uncharacterized protein. (560 aa)
	HCAG_04562	Pre-mRNA processing splicing factor 8. (2739 aa)
	HCAG_04602	Pre-mRNA splicing factor ATP-dependent RNA helicase prp16. (968 aa)
	HCAG_04631	U2 snRNP component HSH155. (1189 aa)
	HCAG_04758	MI domain-containing protein. (589 aa)
	HCAG_08381	Pre-mRNA splicing factor CWC2. (365 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00426	HCAG_00813	A6QSS0	A6QTV7	Uncharacterized protein.	116 kDa U5 small nuclear ribonucleoprotein component.	0.956
HCAG_00426	HCAG_01049	A6QSS0	A6QUJ3	Uncharacterized protein.	Sm domain-containing protein.	0.880
HCAG_00426	HCAG_01196	A6QSS0	A6QUY9	Uncharacterized protein.	Uncharacterized protein.	0.547
HCAG_00426	HCAG_01349	A6QSS0	A6QVE2	Uncharacterized protein.	Uncharacterized protein.	0.985
HCAG_00426	HCAG_01502	A6QSS0	A6QVU5	Uncharacterized protein.	Matrin-type domain-containing protein.	0.459
HCAG_00426	HCAG_02553	A6QSS0	A6QYU6	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.876
HCAG_00426	HCAG_02641	A6QSS0	A6QZ34	Uncharacterized protein.	Pre-mRNA splicing factor syf-1.	0.992
HCAG_00426	HCAG_02780	A6QSS0	A6QZH3	Uncharacterized protein.	Small nuclear ribonucleoprotein G.	0.865
HCAG_00426	HCAG_03195	A6QSS0	A6R0N8	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.837
HCAG_00426	HCAG_03306	A6QSS0	A6R0Z9	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase cypE.	0.791
HCAG_00426	HCAG_03365	A6QSS0	A6R158	Uncharacterized protein.	Uncharacterized protein.	0.972
HCAG_00426	HCAG_03437	A6QSS0	A6R1D0	Uncharacterized protein.	Pre-mRNA splicing factor prp46.	0.992
HCAG_00426	HCAG_03604	A6QSS0	A6R1U6	Uncharacterized protein.	Uncharacterized protein.	0.506
HCAG_00426	HCAG_03763	A6QSS0	A6R2A5	Uncharacterized protein.	RRM domain-containing protein.	0.803
HCAG_00426	HCAG_04232	A6QSS0	A6R3M4	Uncharacterized protein.	Sm domain-containing protein.	0.727
HCAG_00426	HCAG_04402	A6QSS0	A6R444	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.499
HCAG_00426	HCAG_04440	A6QSS0	A6R482	Uncharacterized protein.	Uncharacterized protein.	0.753
HCAG_00426	HCAG_04562	A6QSS0	A6R4K4	Uncharacterized protein.	Pre-mRNA processing splicing factor 8.	0.954
HCAG_00426	HCAG_04602	A6QSS0	A6R4P4	Uncharacterized protein.	Pre-mRNA splicing factor ATP-dependent RNA helicase prp16.	0.996
HCAG_00426	HCAG_04631	A6QSS0	A6R4S3	Uncharacterized protein.	U2 snRNP component HSH155.	0.491