(46 nodes) Protein transmembrane transport network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06381	RING-type domain-containing protein. (313 aa)
	HCAG_08904	Mitochondrial proteins import receptor. (631 aa)
	HCAG_08362	Mitochondrial import receptor subunit Tom20. (175 aa)
	HCAG_08185	Uncharacterized protein. (240 aa)
	HCAG_08101	Mitochondrial import inner membrane translocase subunit tim-16. (139 aa)
	HCAG_08084	Lactamase_B domain-containing protein. (351 aa)
	HCAG_07921	J domain-containing protein. (473 aa)
	HCAG_07242	Uncharacterized protein. (70 aa)
	HCAG_07193	UBIQUITIN_CONJUGAT_2 domain-containing protein. (174 aa)
	HCAG_06176	Mitochondrial import inner membrane translocase subunit tim-14. (104 aa)
	HCAG_05901	DNL-type domain-containing protein. (132 aa)
	HCAG_05856	Uncharacterized protein. (143 aa)
	HCAG_05805	Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family. (677 aa)
	HCAG_07002	Uncharacterized protein. (617 aa)
	HCAG_06882	Mitochondrial import receptor subunit tom-40. (352 aa)
	HCAG_06753	Uncharacterized protein. (338 aa)
	HCAG_06626	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (500 aa)
	HCAG_06516	Pex2_Pex12 domain-containing protein. (508 aa)
	HCAG_06368	Uncharacterized protein. (1155 aa)
	HCAG_05373	Uncharacterized protein. (141 aa)
	HCAG_05309	Uncharacterized protein. (196 aa)
	HCAG_04943	10 kDa heat shock protein, mitochondrial; Belongs to the GroES chaperonin family. (90 aa)
	HCAG_04830	Uncharacterized protein. (285 aa)
	HCAG_04580	Peroxisomal biogenesis factor 2. (466 aa)
	HCAG_04515	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (551 aa)
	HCAG_04365	Sulfhydryl oxidase. (158 aa)
	HCAG_04005	Mitochondrial import inner membrane translocase subunit tim23. (213 aa)
	HCAG_03787	Uncharacterized protein. (376 aa)
	HCAG_03758	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (252 aa)
	HCAG_02998	Protein transport protein SEC61 alpha subunit. (479 aa)
	HCAG_02806	Peroxisomal targeting signal receptor. (496 aa)
	HCAG_02803	SH3 domain-containing protein. (462 aa)
	HCAG_02663	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (928 aa)
	HCAG_02415	J domain-containing protein. (680 aa)
	HCAG_01990	Uncharacterized protein. (507 aa)
	HCAG_01494	DUF2263 domain-containing protein. (376 aa)
	HCAG_01443	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (520 aa)
	HCAG_01398	Heat shock 70 kDa protein 7. (311 aa)
	HCAG_00825	Uncharacterized protein. (259 aa)
	HCAG_00665	Uncharacterized protein. (233 aa)
	HCAG_00570	SRP54 domain-containing protein. (353 aa)
	HCAG_00569	Uncharacterized protein. (103 aa)
	HCAG_00357	Mitochondrial import inner membrane translocase subunit tim22. (494 aa)
	HCAG_00356	Mitochondrial import inner membrane translocase subunit tim22. (183 aa)
	HCAG_00346	CHY-type domain-containing protein. (122 aa)
	HCAG_00090	Pex14_N domain-containing protein. (359 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00090	HCAG_02663	A6QRT4	A6QZ56	Pex14_N domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.448
HCAG_00090	HCAG_02803	A6QRT4	A6QZJ6	Pex14_N domain-containing protein.	SH3 domain-containing protein.	0.999
HCAG_00090	HCAG_02806	A6QRT4	A6QZJ9	Pex14_N domain-containing protein.	Peroxisomal targeting signal receptor.	0.999
HCAG_00090	HCAG_06368	A6QRT4	A6R7S7	Pex14_N domain-containing protein.	Uncharacterized protein.	0.886
HCAG_00090	HCAG_06381	A6QRT4	A6R7U0	Pex14_N domain-containing protein.	RING-type domain-containing protein.	0.915
HCAG_00090	HCAG_06516	A6QRT4	A6R875	Pex14_N domain-containing protein.	Pex2_Pex12 domain-containing protein.	0.930
HCAG_00090	HCAG_06753	A6QRT4	A6R8W2	Pex14_N domain-containing protein.	Uncharacterized protein.	0.962
HCAG_00090	HCAG_07193	A6QRT4	A6RC35	Pex14_N domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.829
HCAG_00356	HCAG_01443	A6QSK0	A6QVN6	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.596
HCAG_00356	HCAG_03758	A6QSK0	A6R2A0	Mitochondrial import inner membrane translocase subunit tim22.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.426
HCAG_00356	HCAG_04005	A6QSK0	A6R2Z7	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import inner membrane translocase subunit tim23.	0.903
HCAG_00356	HCAG_04515	A6QSK0	A6R4F7	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.558
HCAG_00356	HCAG_05309	A6QSK0	A6R6Q1	Mitochondrial import inner membrane translocase subunit tim22.	Uncharacterized protein.	0.728
HCAG_00356	HCAG_05856	A6QSK0	A6RA68	Mitochondrial import inner membrane translocase subunit tim22.	Uncharacterized protein.	0.732
HCAG_00356	HCAG_06176	A6QSK0	A6RB38	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import inner membrane translocase subunit tim-14.	0.566
HCAG_00356	HCAG_06882	A6QSK0	A6R991	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import receptor subunit tom-40.	0.537
HCAG_00356	HCAG_08084	A6QSK0	A6REL9	Mitochondrial import inner membrane translocase subunit tim22.	Lactamase_B domain-containing protein.	0.477
HCAG_00356	HCAG_08101	A6QSK0	A6REN6	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial import inner membrane translocase subunit tim-16.	0.515
HCAG_00356	HCAG_08185	A6QSK0	A6REX0	Mitochondrial import inner membrane translocase subunit tim22.	Uncharacterized protein.	0.550
HCAG_00356	HCAG_08904	A6QSK0	A6RGY7	Mitochondrial import inner membrane translocase subunit tim22.	Mitochondrial proteins import receptor.	0.406