(73 nodes) Fungal-type vacuole network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06506	SAC domain-containing protein. (943 aa)
	HCAG_06560	PHB domain-containing protein. (356 aa)
	HCAG_06609	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1266 aa)
	HCAG_06746	Uncharacterized protein. (538 aa)
	HCAG_05799	acidPPc domain-containing protein. (319 aa)
	HCAG_05976	Uncharacterized protein. (611 aa)
	HCAG_06136	Uncharacterized protein. (511 aa)
	HCAG_07080	Uncharacterized protein. (197 aa)
	HCAG_07083	Aminopeptidase 2. (1037 aa)
	HCAG_07324	Uncharacterized protein. (407 aa)
	HCAG_07440	Leucine aminopeptidase 2; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro). (623 aa)
	HCAG_07780	PIPK domain-containing protein. (1683 aa)
	HCAG_08166	Uncharacterized protein. (402 aa)
	HCAG_08352	Uncharacterized protein; Belongs to the synaptobrevin family. (273 aa)
	HCAG_08559	Uncharacterized protein. (512 aa)
	HCAG_08631	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (647 aa)
	CPYA	Carboxypeptidase Y homolog A; Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity). (545 aa)
	HCAG_08794	Uncharacterized protein. (561 aa)
	HCAG_08804	Uncharacterized protein. (892 aa)
	HCAG_04551	Uncharacterized protein. (616 aa)
	HCAG_04595	MFS domain-containing protein. (532 aa)
	HCAG_04780	Uncharacterized protein. (306 aa)
	HCAG_04842	Uncharacterized protein. (806 aa)
	HCAG_04990	Uncharacterized protein. (57 aa)
	HCAG_05103	MFS domain-containing protein. (572 aa)
	HCAG_05171	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (690 aa)
	HCAG_05256	MFS domain-containing protein. (501 aa)
	HCAG_05258	Altered inheritance of mitochondria protein 24, mitochondrial. (124 aa)
	HCAG_05485	Uncharacterized protein. (157 aa)
	HCAG_05586	Uncharacterized protein. (835 aa)
	HCAG_05598	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (270 aa)
	HCAG_06484	Uncharacterized protein. (260 aa)
	HCAG_00065	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (328 aa)
	HCAG_00330	Uncharacterized protein. (617 aa)
	HCAG_00403	Vacuolar sorting protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (681 aa)
	HCAG_00621	Amino acid permease Dip5. (570 aa)
	HCAG_00653	Aa_trans domain-containing protein. (533 aa)
	HCAG_00654	Uncharacterized protein; Belongs to the BI1 family. (187 aa)
	HCAG_00709	Metallophos domain-containing protein. (505 aa)
	HCAG_00795	Uncharacterized protein. (312 aa)
	HCAG_00937	DEP domain-containing protein. (1754 aa)
	HCAG_01074	Uncharacterized protein. (339 aa)
	HCAG_01135	PKD_channel domain-containing protein. (489 aa)
	HCAG_01266	Uncharacterized protein. (388 aa)
	HCAG_01299	Uncharacterized protein. (358 aa)
	HCAG_01334	Uncharacterized protein. (389 aa)
	HCAG_01451	Uncharacterized protein. (684 aa)
	HCAG_01466	acidPPc domain-containing protein. (373 aa)
	HCAG_01774	Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1400 aa)
	HCAG_01923	Uncharacterized protein. (588 aa)
	HCAG_02037	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family. (432 aa)
	HCAG_02592	Uncharacterized protein. (386 aa)
	HCAG_03001	Uncharacterized protein. (250 aa)
	HCAG_03002	Uncharacterized protein. (122 aa)
	HCAG_03053	Uncharacterized protein. (595 aa)
	HCAG_03238	Uncharacterized protein. (585 aa)
	HCAG_03246	G_PROTEIN_RECEP_F1_2 domain-containing protein. (430 aa)
	HCAG_03483	Uncharacterized protein. (396 aa)
	HCAG_03556	Uncharacterized protein. (270 aa)
	HCAG_03601	Uncharacterized protein. (521 aa)
	HCAG_03799	F-box domain-containing protein. (648 aa)
	HCAG_03891	L-type lectin-like domain-containing protein. (330 aa)
	HCAG_03916	MFS domain-containing protein. (437 aa)
	HCAG_03943	MFS domain-containing protein. (432 aa)
	HCAG_03953	CNH domain-containing protein. (1057 aa)
	HCAG_04155	N-acetyltransferase domain-containing protein. (293 aa)
	HCAG_04157	MFS domain-containing protein. (432 aa)
	HCAG_04234	Uncharacterized protein. (660 aa)
	HCAG_04254	DUF202 domain-containing protein. (402 aa)
	HCAG_04257	Zinc homeostasis factor 1. (525 aa)
	HCAG_04275	Uncharacterized protein. (154 aa)
	HCAG_04327	Uncharacterized protein. (558 aa)
	HCAG_04504	MFS domain-containing protein. (520 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00653	HCAG_00654	A6QTE7	A6QTE8	Aa_trans domain-containing protein.	Uncharacterized protein; Belongs to the BI1 family.	0.522
HCAG_00653	HCAG_04234	A6QTE7	A6R3M6	Aa_trans domain-containing protein.	Uncharacterized protein.	0.481
HCAG_00654	HCAG_00653	A6QTE8	A6QTE7	Uncharacterized protein; Belongs to the BI1 family.	Aa_trans domain-containing protein.	0.522
HCAG_00937	HCAG_01451	A6QU81	A6QVP4	DEP domain-containing protein.	Uncharacterized protein.	0.999
HCAG_00937	HCAG_03601	A6QU81	A6R1U3	DEP domain-containing protein.	Uncharacterized protein.	0.997
HCAG_01299	HCAG_04780	A6QV92	A6R572	Uncharacterized protein.	Uncharacterized protein.	0.610
HCAG_01451	HCAG_00937	A6QVP4	A6QU81	Uncharacterized protein.	DEP domain-containing protein.	0.999
HCAG_01451	HCAG_03601	A6QVP4	A6R1U3	Uncharacterized protein.	Uncharacterized protein.	0.998
HCAG_01923	HCAG_06560	A6QX16	A6R8B9	Uncharacterized protein.	PHB domain-containing protein.	0.618
HCAG_02037	HCAG_04234	A6QXD0	A6R3M6	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	Uncharacterized protein.	0.557
HCAG_03601	HCAG_00937	A6R1U3	A6QU81	Uncharacterized protein.	DEP domain-containing protein.	0.997
HCAG_03601	HCAG_01451	A6R1U3	A6QVP4	Uncharacterized protein.	Uncharacterized protein.	0.998
HCAG_03799	HCAG_04780	A6R2E1	A6R572	F-box domain-containing protein.	Uncharacterized protein.	0.413
HCAG_03953	HCAG_05598	A6R2U5	A6R7J0	CNH domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.672
HCAG_03953	HCAG_08352	A6R2U5	A6RFD6	CNH domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.447
HCAG_04234	HCAG_00653	A6R3M6	A6QTE7	Uncharacterized protein.	Aa_trans domain-containing protein.	0.481
HCAG_04234	HCAG_02037	A6R3M6	A6QXD0	Uncharacterized protein.	Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.	0.557
HCAG_04234	HCAG_07780	A6R3M6	A6RDS2	Uncharacterized protein.	PIPK domain-containing protein.	0.538
HCAG_04254	HCAG_04257	A6R3P6	A6R3P9	DUF202 domain-containing protein.	Zinc homeostasis factor 1.	0.556
HCAG_04254	HCAG_07324	A6R3P6	A6RCG6	DUF202 domain-containing protein.	Uncharacterized protein.	0.413