(10 nodes) AP-type membrane coat adaptor complex network (Histoplasma capsulatum NAm1)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	HCAG_01154	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
	HCAG_04074	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (965 aa)
	HCAG_04363	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (711 aa)
	HCAG_06724	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	HCAG_07062	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (579 aa)
	HCAG_07753	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (993 aa)
	HCAG_08087	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (692 aa)
	HCAG_00157	AP-1 complex subunit gamma. (765 aa)
	HCAG_00869	Adaptin_N domain-containing protein. (753 aa)
	HCAG_00950	Rad60-SLD_2 domain-containing protein. (288 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00157	HCAG_00869	A6QS01	A6QU13	AP-1 complex subunit gamma.	Adaptin_N domain-containing protein.	0.960
HCAG_00157	HCAG_00950	A6QS01	A6QU94	AP-1 complex subunit gamma.	Rad60-SLD_2 domain-containing protein.	0.924
HCAG_00157	HCAG_01154	A6QS01	A6QUU8	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00157	HCAG_04074	A6QS01	A6R366	AP-1 complex subunit gamma.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.485
HCAG_00157	HCAG_04363	A6QS01	A6R405	AP-1 complex subunit gamma.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.924
HCAG_00157	HCAG_06724	A6QS01	A6R8T3	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.956
HCAG_00157	HCAG_07062	A6QS01	A6RBQ4	AP-1 complex subunit gamma.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.893
HCAG_00157	HCAG_07753	A6QS01	A6RDP5	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.447
HCAG_00157	HCAG_08087	A6QS01	A6REM2	AP-1 complex subunit gamma.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.924
HCAG_00869	HCAG_00157	A6QU13	A6QS01	Adaptin_N domain-containing protein.	AP-1 complex subunit gamma.	0.960
HCAG_00869	HCAG_00950	A6QU13	A6QU94	Adaptin_N domain-containing protein.	Rad60-SLD_2 domain-containing protein.	0.518
HCAG_00869	HCAG_01154	A6QU13	A6QUU8	Adaptin_N domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.808
HCAG_00869	HCAG_04074	A6QU13	A6R366	Adaptin_N domain-containing protein.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.997
HCAG_00869	HCAG_04363	A6QU13	A6R405	Adaptin_N domain-containing protein.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.518
HCAG_00869	HCAG_07062	A6QU13	A6RBQ4	Adaptin_N domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.995
HCAG_00869	HCAG_08087	A6QU13	A6REM2	Adaptin_N domain-containing protein.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.518
HCAG_00950	HCAG_00157	A6QU94	A6QS01	Rad60-SLD_2 domain-containing protein.	AP-1 complex subunit gamma.	0.924
HCAG_00950	HCAG_00869	A6QU94	A6QU13	Rad60-SLD_2 domain-containing protein.	Adaptin_N domain-containing protein.	0.518
HCAG_00950	HCAG_01154	A6QU94	A6QUU8	Rad60-SLD_2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.904
HCAG_00950	HCAG_04074	A6QU94	A6R366	Rad60-SLD_2 domain-containing protein.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.802