(23 nodes) Clathrin-coated vesicle network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06724	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	HCAG_08861	Uncharacterized protein. (427 aa)
	HCAG_08087	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (692 aa)
	HCAG_07987	ENTH domain-containing protein. (682 aa)
	HCAG_07753	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (993 aa)
	HCAG_00157	AP-1 complex subunit gamma. (765 aa)
	HCAG_00598	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family. (422 aa)
	HCAG_00821	Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily. (590 aa)
	HCAG_00874	DUF1681 domain-containing protein. (353 aa)
	HCAG_00950	Rad60-SLD_2 domain-containing protein. (288 aa)
	HCAG_01154	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (152 aa)
	HCAG_01167	I/LWEQ domain-containing protein. (1031 aa)
	HCAG_01328	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
	HCAG_02232	Uncharacterized protein. (140 aa)
	HCAG_02233	SAC domain-containing protein. (707 aa)
	HCAG_02478	Uncharacterized protein. (744 aa)
	HCAG_02567	LDB19 domain-containing protein. (547 aa)
	HCAG_03231	Uncharacterized protein. (423 aa)
	HCAG_04363	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (711 aa)
	HCAG_04492	ENTH domain-containing protein. (541 aa)
	HCAG_05223	ENTH domain-containing protein. (447 aa)
	HCAG_06633	Uncharacterized protein. (693 aa)
	HCAG_07263	Uncharacterized protein. (801 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00157	HCAG_00598	A6QS01	A6QT92	AP-1 complex subunit gamma.	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.999
HCAG_00157	HCAG_00874	A6QS01	A6QU18	AP-1 complex subunit gamma.	DUF1681 domain-containing protein.	0.772
HCAG_00157	HCAG_00950	A6QS01	A6QU94	AP-1 complex subunit gamma.	Rad60-SLD_2 domain-containing protein.	0.924
HCAG_00157	HCAG_01154	A6QS01	A6QUU8	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00157	HCAG_01167	A6QS01	A6QUW1	AP-1 complex subunit gamma.	I/LWEQ domain-containing protein.	0.685
HCAG_00157	HCAG_01328	A6QS01	A6QVC1	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.876
HCAG_00157	HCAG_04363	A6QS01	A6R405	AP-1 complex subunit gamma.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.924
HCAG_00157	HCAG_04492	A6QS01	A6R4D4	AP-1 complex subunit gamma.	ENTH domain-containing protein.	0.590
HCAG_00157	HCAG_05223	A6QS01	A6R6G5	AP-1 complex subunit gamma.	ENTH domain-containing protein.	0.573
HCAG_00157	HCAG_06724	A6QS01	A6R8T3	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.956
HCAG_00157	HCAG_07263	A6QS01	A6RCA5	AP-1 complex subunit gamma.	Uncharacterized protein.	0.573
HCAG_00157	HCAG_07753	A6QS01	A6RDP5	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.447
HCAG_00157	HCAG_07987	A6QS01	A6REC2	AP-1 complex subunit gamma.	ENTH domain-containing protein.	0.735
HCAG_00157	HCAG_08087	A6QS01	A6REM2	AP-1 complex subunit gamma.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.924
HCAG_00598	HCAG_00157	A6QT92	A6QS01	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.999
HCAG_00598	HCAG_00874	A6QT92	A6QU18	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	DUF1681 domain-containing protein.	0.603
HCAG_00598	HCAG_00950	A6QT92	A6QU94	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	Rad60-SLD_2 domain-containing protein.	0.904
HCAG_00598	HCAG_01154	A6QT92	A6QUU8	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
HCAG_00598	HCAG_01167	A6QT92	A6QUW1	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	I/LWEQ domain-containing protein.	0.621
HCAG_00598	HCAG_01328	A6QT92	A6QVC1	AP-1 adaptor complex subunit mu; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.881