(7 nodes) HOPS complex network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05963	DSBA domain-containing protein. (186 aa)
	HCAG_00327	E3 ubiquitin-protein ligase PEP5. (935 aa)
	HCAG_02495	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (755 aa)
	HCAG_03953	CNH domain-containing protein. (1057 aa)
	HCAG_04807	Vps8 domain-containing protein. (1267 aa)
	HCAG_06571	Uncharacterized protein. (1095 aa)
	HCAG_09050	Pep3_Vps18 domain-containing protein. (953 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00327	HCAG_02495	A6QSH1	A6QYN8	E3 ubiquitin-protein ligase PEP5.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.995
HCAG_00327	HCAG_03953	A6QSH1	A6R2U5	E3 ubiquitin-protein ligase PEP5.	CNH domain-containing protein.	0.995
HCAG_00327	HCAG_04807	A6QSH1	A6R599	E3 ubiquitin-protein ligase PEP5.	Vps8 domain-containing protein.	0.993
HCAG_00327	HCAG_06571	A6QSH1	A6R8D0	E3 ubiquitin-protein ligase PEP5.	Uncharacterized protein.	0.995
HCAG_00327	HCAG_09050	A6QSH1	A6RHD3	E3 ubiquitin-protein ligase PEP5.	Pep3_Vps18 domain-containing protein.	0.995
HCAG_02495	HCAG_00327	A6QYN8	A6QSH1	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	E3 ubiquitin-protein ligase PEP5.	0.995
HCAG_02495	HCAG_03953	A6QYN8	A6R2U5	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	CNH domain-containing protein.	0.996
HCAG_02495	HCAG_04807	A6QYN8	A6R599	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vps8 domain-containing protein.	0.905
HCAG_02495	HCAG_06571	A6QYN8	A6R8D0	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Uncharacterized protein.	0.995
HCAG_02495	HCAG_09050	A6QYN8	A6RHD3	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Pep3_Vps18 domain-containing protein.	0.995
HCAG_03953	HCAG_00327	A6R2U5	A6QSH1	CNH domain-containing protein.	E3 ubiquitin-protein ligase PEP5.	0.995
HCAG_03953	HCAG_02495	A6R2U5	A6QYN8	CNH domain-containing protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.996
HCAG_03953	HCAG_04807	A6R2U5	A6R599	CNH domain-containing protein.	Vps8 domain-containing protein.	0.887
HCAG_03953	HCAG_06571	A6R2U5	A6R8D0	CNH domain-containing protein.	Uncharacterized protein.	0.995
HCAG_03953	HCAG_09050	A6R2U5	A6RHD3	CNH domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.995
HCAG_04807	HCAG_00327	A6R599	A6QSH1	Vps8 domain-containing protein.	E3 ubiquitin-protein ligase PEP5.	0.993
HCAG_04807	HCAG_02495	A6R599	A6QYN8	Vps8 domain-containing protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.905
HCAG_04807	HCAG_03953	A6R599	A6R2U5	Vps8 domain-containing protein.	CNH domain-containing protein.	0.887
HCAG_04807	HCAG_06571	A6R599	A6R8D0	Vps8 domain-containing protein.	Uncharacterized protein.	0.670
HCAG_04807	HCAG_09050	A6R599	A6RHD3	Vps8 domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.993