60 items (Histoplasma capsulatum NAm1) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_06417	DNA-directed RNA polymerase II 13.3 kDa polypeptide. (168 aa)
	HCAG_06934	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (506 aa)
	RPC82	DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). (649 aa)
	HCAG_05932	RPOLD domain-containing protein. (576 aa)
	HCAG_07073	RING-type domain-containing protein. (379 aa)
	HCAG_07353	HTH TFE/IIEalpha-type domain-containing protein. (441 aa)
	HCAG_07360	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa)
	HCAG_07638	Uncharacterized protein. (720 aa)
	HCAG_07759	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (455 aa)
	HCAG_07839	CDC73_C domain-containing protein. (519 aa)
	HCAG_07976	Acyl_transf_3 domain-containing protein. (459 aa)
	HCAG_08069	Uncharacterized protein. (544 aa)
	HCAG_08207	Uncharacterized protein. (344 aa)
	HCAG_08226	RNA_pol_L_2 domain-containing protein. (137 aa)
	HCAG_08300	BTP domain-containing protein. (214 aa)
	HCAG_08301	TAFII55_N domain-containing protein. (559 aa)
	HCAG_08707	DNA polymerase. (1458 aa)
	HCAG_08810	Uncharacterized protein. (684 aa)
	HCAG_08845	Plus3 domain-containing protein. (637 aa)
	HCAG_08886	Uncharacterized protein. (371 aa)
	HCAG_08910	DNA repair protein Rex1. (72 aa)
	HCAG_01496	Uncharacterized protein. (75 aa)
	HCAG_01307	DUF4211 domain-containing protein. (223 aa)
	HCAG_01284	RPAP1_C domain-containing protein. (257 aa)
	HCAG_02380	Uncharacterized protein. (445 aa)
	HCAG_01249	TFIID_20kDa domain-containing protein. (73 aa)
	HCAG_01248	Uncharacterized protein. (414 aa)
	HCAG_01023	Uncharacterized protein. (396 aa)
	HCAG_01022	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	HCAG_00906	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (129 aa)
	HCAG_00857	Uncharacterized protein. (352 aa)
	HCAG_00846	Uncharacterized protein. (413 aa)
	HCAG_00645	Uncharacterized protein. (296 aa)
	HCAG_00556	TAF domain-containing protein. (472 aa)
	HCAG_00496	Uncharacterized protein. (750 aa)
	HCAG_00360	Acyl_transf_3 domain-containing protein. (189 aa)
	HCAG_02903	CYCLIN domain-containing protein; Belongs to the cyclin family. (491 aa)
	HCAG_02833	Uncharacterized protein. (369 aa)
	HCAG_02781	Transcription initiation factor TFIId 127kD subunit. (1170 aa)
	HCAG_02518	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (626 aa)
	HCAG_01948	Uncharacterized protein. (392 aa)
	HCAG_01650	UmuC domain-containing protein. (744 aa)
	HCAG_01528	Uncharacterized protein. (644 aa)
	HCAG_02360	Uncharacterized protein. (324 aa)
	HCAG_04624	DNA-directed RNA polymerases I and III 40 kDa polypeptide. (380 aa)
	HCAG_04472	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (363 aa)
	HCAG_04412	Uncharacterized protein. (382 aa)
	HCAG_04046	Serine/threonine-protein kinase crk1; Belongs to the protein kinase superfamily. (408 aa)
	HCAG_02005	WD_REPEATS_REGION domain-containing protein. (326 aa)
	HCAG_03024	Uncharacterized protein. (1227 aa)
	HCAG_01970	Uncharacterized protein. (334 aa)
	HCAG_01955	Uncharacterized protein. (173 aa)
	HCAG_03412	BRCT domain-containing protein. (718 aa)
	HCAG_03552	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
	HCAG_03746	DUF3591 domain-containing protein. (1092 aa)
	HCAG_04738	Uncharacterized protein. (201 aa)
	HCAG_04750	Uncharacterized protein. (715 aa)
	HCAG_04789	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (668 aa)
	HCAG_04790	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (536 aa)
	HCAG_05207	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (298 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00360	HCAG_00496	A6QSK4	A6QSZ0	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.738
HCAG_00360	HCAG_00556	A6QSK4	A6QT50	Acyl_transf_3 domain-containing protein.	TAF domain-containing protein.	0.948
HCAG_00360	HCAG_00645	A6QSK4	A6QTD9	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.635
HCAG_00360	HCAG_00846	A6QSK4	A6QTZ0	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.738
HCAG_00360	HCAG_00857	A6QSK4	A6QU01	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.950
HCAG_00360	HCAG_00906	A6QSK4	A6QU50	Acyl_transf_3 domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.771
HCAG_00360	HCAG_01022	A6QSK4	A6QUG6	Acyl_transf_3 domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.776
HCAG_00360	HCAG_01023	A6QSK4	A6QUG7	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.776
HCAG_00360	HCAG_01248	A6QSK4	A6QV41	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.867
HCAG_00360	HCAG_01249	A6QSK4	A6QV42	Acyl_transf_3 domain-containing protein.	TFIID_20kDa domain-containing protein.	0.867
HCAG_00360	HCAG_01307	A6QSK4	A6QVA0	Acyl_transf_3 domain-containing protein.	DUF4211 domain-containing protein.	0.789
HCAG_00360	HCAG_01496	A6QSK4	A6QVT9	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.738
HCAG_00360	HCAG_01528	A6QSK4	A6QVX1	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.746
HCAG_00360	HCAG_01948	A6QSK4	A6QX41	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.789
HCAG_00360	HCAG_01955	A6QSK4	A6QX48	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.948
HCAG_00360	HCAG_02360	A6QSK4	A6QYA3	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.947
HCAG_00360	HCAG_02380	A6QSK4	A6QYC3	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.785
HCAG_00360	HCAG_02781	A6QSK4	A6QZH4	Acyl_transf_3 domain-containing protein.	Transcription initiation factor TFIId 127kD subunit.	0.948
HCAG_00360	HCAG_02833	A6QSK4	A6QZM6	Acyl_transf_3 domain-containing protein.	Uncharacterized protein.	0.779
HCAG_00360	HCAG_02903	A6QSK4	A6QZU6	Acyl_transf_3 domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.758