(33 nodes) Small GTP-binding protein domain network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05502	Tr-type G domain-containing protein. (777 aa)
	HCAG_00107	Uncharacterized protein. (197 aa)
	HCAG_00221	OBG-type G domain-containing protein. (351 aa)
	HCAG_00675	Uncharacterized protein. (249 aa)
	HCAG_00813	116 kDa U5 small nuclear ribonucleoprotein component. (899 aa)
	HCAG_00894	Protein ras-1. (149 aa)
	HCAG_01041	GTP-binding protein ryh1. (232 aa)
	HCAG_01053	Uncharacterized protein. (187 aa)
	HCAG_01183	Protein rho2. (199 aa)
	HCAG_01241	Protein Rho3. (206 aa)
	HCAG_01847	ADP-ribosylation factor. (723 aa)
	HCAG_02049	Uncharacterized protein. (325 aa)
	HCAG_02425	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	HCAG_02618	GTP-binding protein YPT7. (216 aa)
	MEF2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (871 aa)
	HCAG_03115	Uncharacterized protein. (187 aa)
	HCAG_04840	GTP-binding protein sarA; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
	HCAG_05560	Uncharacterized protein. (192 aa)
	HCAG_06619	GTP-binding protein YPT52. (285 aa)
	HCAG_06851	F-box domain-containing protein. (1231 aa)
	HCAG_06941	GTP-binding protein ypt1. (204 aa)
	HCAG_06999	Rab1a. (210 aa)
	HCAG_05804	Tr-type G domain-containing protein. (957 aa)
	HCAG_05908	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	HCAG_05988	Tr-type G domain-containing protein. (631 aa)
	HCAG_06015	Tr-type G domain-containing protein. (1068 aa)
	HCAG_06255	Elongation factor G. (351 aa)
	HCAG_06262	GTP-binding protein ypt5. (181 aa)
	HCAG_07540	Uncharacterized protein. (287 aa)
	HCAG_07659	GTP-binding protein SAS1. (205 aa)
	HCAG_08067	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	HCAG_08382	GTP-binding protein 1. (363 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (657 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GUF1	HCAG_05502	A6RGX9	A6R794	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Tr-type G domain-containing protein.	0.448
HCAG_00107	HCAG_00894	A6QRV1	A6QU38	Uncharacterized protein.	Protein ras-1.	0.446
HCAG_00107	HCAG_01053	A6QRV1	A6QUJ7	Uncharacterized protein.	Uncharacterized protein.	0.421
HCAG_00107	HCAG_01183	A6QRV1	A6QUX7	Uncharacterized protein.	Protein rho2.	0.693
HCAG_00107	HCAG_02618	A6QRV1	A6QZ11	Uncharacterized protein.	GTP-binding protein YPT7.	0.555
HCAG_00107	HCAG_06262	A6QRV1	A6RBC4	Uncharacterized protein.	GTP-binding protein ypt5.	0.453
HCAG_00107	HCAG_07659	A6QRV1	A6RDF1	Uncharacterized protein.	GTP-binding protein SAS1.	0.492
HCAG_00221	HCAG_08382	A6QS65	A6RFG6	OBG-type G domain-containing protein.	GTP-binding protein 1.	0.610
HCAG_00675	HCAG_01183	A6QTG9	A6QUX7	Uncharacterized protein.	Protein rho2.	0.634
HCAG_00675	HCAG_02425	A6QTG9	A6QYG8	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.400
HCAG_00813	HCAG_05502	A6QTV7	A6R794	116 kDa U5 small nuclear ribonucleoprotein component.	Tr-type G domain-containing protein.	0.594
HCAG_00813	HCAG_06015	A6QTV7	A6RAM7	116 kDa U5 small nuclear ribonucleoprotein component.	Tr-type G domain-containing protein.	0.604
HCAG_00894	HCAG_00107	A6QU38	A6QRV1	Protein ras-1.	Uncharacterized protein.	0.446
HCAG_00894	HCAG_01053	A6QU38	A6QUJ7	Protein ras-1.	Uncharacterized protein.	0.433
HCAG_00894	HCAG_01183	A6QU38	A6QUX7	Protein ras-1.	Protein rho2.	0.641
HCAG_00894	HCAG_02425	A6QU38	A6QYG8	Protein ras-1.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.400
HCAG_00894	HCAG_05560	A6QU38	A6R7F2	Protein ras-1.	Uncharacterized protein.	0.428
HCAG_01041	HCAG_01847	A6QUI5	A6QWU0	GTP-binding protein ryh1.	ADP-ribosylation factor.	0.490
HCAG_01041	HCAG_02049	A6QUI5	A6QXE2	GTP-binding protein ryh1.	Uncharacterized protein.	0.568
HCAG_01041	HCAG_02618	A6QUI5	A6QZ11	GTP-binding protein ryh1.	GTP-binding protein YPT7.	0.673