(11 nodes) Ribosomal protein L2, domain 2 network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_05559	Uncharacterized protein. (357 aa)
	HCAG_06021	Eukaryotic translation initiation factor 5A. (161 aa)
	HCAG_06230	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1080 aa)
	HCAG_07237	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (262 aa)
	HCAG_08351	KOW domain-containing protein. (135 aa)
	HCAG_08515	60S ribosomal protein L2. (254 aa)
	HCAG_01793	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (204 aa)
	HCAG_01477	60S ribosomal protein RML2, mitochondrial. (374 aa)
	HCAG_00683	Woronin body major protein. (311 aa)
	HCAG_00485	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1327 aa)
	HCAG_05100	Ribosomal_L14e domain-containing protein. (113 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00485	HCAG_05100	A6QSX9	A6R642	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	Ribosomal_L14e domain-containing protein.	0.451
HCAG_00485	HCAG_07237	A6QSX9	A6RC79	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.470
HCAG_00485	HCAG_08351	A6QSX9	A6RFD5	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	KOW domain-containing protein.	0.488
HCAG_00485	HCAG_08515	A6QSX9	A6RFU9	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	60S ribosomal protein L2.	0.465
HCAG_00683	HCAG_01477	A6QTH7	A6QVS0	Woronin body major protein.	60S ribosomal protein RML2, mitochondrial.	0.842
HCAG_00683	HCAG_01793	A6QTH7	A6QWN6	Woronin body major protein.	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	0.898
HCAG_00683	HCAG_05100	A6QTH7	A6R642	Woronin body major protein.	Ribosomal_L14e domain-containing protein.	0.916
HCAG_00683	HCAG_07237	A6QTH7	A6RC79	Woronin body major protein.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.850
HCAG_00683	HCAG_08351	A6QTH7	A6RFD5	Woronin body major protein.	KOW domain-containing protein.	0.908
HCAG_00683	HCAG_08515	A6QTH7	A6RFU9	Woronin body major protein.	60S ribosomal protein L2.	0.894
HCAG_01477	HCAG_00683	A6QVS0	A6QTH7	60S ribosomal protein RML2, mitochondrial.	Woronin body major protein.	0.842
HCAG_01477	HCAG_01793	A6QVS0	A6QWN6	60S ribosomal protein RML2, mitochondrial.	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	0.870
HCAG_01477	HCAG_05100	A6QVS0	A6R642	60S ribosomal protein RML2, mitochondrial.	Ribosomal_L14e domain-containing protein.	0.870
HCAG_01477	HCAG_05559	A6QVS0	A6R7F1	60S ribosomal protein RML2, mitochondrial.	Uncharacterized protein.	0.499
HCAG_01477	HCAG_06021	A6QVS0	A6RAN3	60S ribosomal protein RML2, mitochondrial.	Eukaryotic translation initiation factor 5A.	0.842
HCAG_01477	HCAG_07237	A6QVS0	A6RC79	60S ribosomal protein RML2, mitochondrial.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.909
HCAG_01477	HCAG_08351	A6QVS0	A6RFD5	60S ribosomal protein RML2, mitochondrial.	KOW domain-containing protein.	0.981
HCAG_01793	HCAG_00683	A6QWN6	A6QTH7	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	Woronin body major protein.	0.898
HCAG_01793	HCAG_01477	A6QWN6	A6QVS0	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	60S ribosomal protein RML2, mitochondrial.	0.870
HCAG_01793	HCAG_05100	A6QWN6	A6R642	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	Ribosomal_L14e domain-containing protein.	0.999