(69 nodes) FAD/NAD(P)-binding domain superfamily network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_08320	Uncharacterized protein. (526 aa)
	HCAG_00023	GMC_OxRdtase_N domain-containing protein; Belongs to the GMC oxidoreductase family. (438 aa)
	HCAG_00081	DAO domain-containing protein. (482 aa)
	HCAG_00085	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (643 aa)
	HCAG_00342	Uncharacterized protein. (602 aa)
	HCAG_00435	Pyr_redox_2 domain-containing protein. (392 aa)
	HCAG_00529	Uncharacterized protein; Belongs to the FMO family. (500 aa)
	HCAG_00587	Uncharacterized protein. (570 aa)
	HCAG_00662	Uncharacterized protein. (679 aa)
	HCAG_00787	DAO domain-containing protein. (344 aa)
	HCAG_00896	FAD_binding_3 domain-containing protein. (448 aa)
	HCAG_00968	EF-hand domain-containing protein. (615 aa)
	HCAG_01044	FAD_binding_3 domain-containing protein. (148 aa)
	HCAG_01207	Uncharacterized protein. (698 aa)
	HCAG_01268	GMC_OxRdtase_N domain-containing protein. (511 aa)
	HCAG_01305	Pyr_redox_2 domain-containing protein. (651 aa)
	HCAG_01577	Uncharacterized protein. (565 aa)
	HCAG_01674	Uncharacterized protein. (449 aa)
	HCAG_01883	Uncharacterized protein. (604 aa)
	HCAG_02011	Glycerol-3-phosphate dehydrogenase, mitochondrial. (683 aa)
	HCAG_02012	FAD_binding_3 domain-containing protein. (413 aa)
	HCAG_02133	Uncharacterized protein. (388 aa)
	HCAG_02141	Long-chain-alcohol oxidase. (737 aa)
	HCAG_02219	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (475 aa)
	HCAG_02304	Pyr_redox_2 domain-containing protein. (470 aa)
	HCAG_02745	Uncharacterized protein. (264 aa)
	HCAG_02746	GMC_oxred_C domain-containing protein. (54 aa)
	HCAG_02844	Uncharacterized protein. (539 aa)
	HCAG_02957	SE domain-containing protein. (484 aa)
	HCAG_03194	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (547 aa)
	HCAG_03259	FAD_binding_3 domain-containing protein. (603 aa)
	HCAG_03323	Fumarate reductase; Irreversibly catalyzes the reduction of fumarate to succinate. (565 aa)
	HCAG_03482	Uncharacterized protein. (546 aa)
	HCAG_03785	NADPH:adrenodoxin oxidoreductase, mitochondrial. (489 aa)
	HCAG_03831	Uncharacterized protein. (475 aa)
	HCAG_03840	Uncharacterized protein. (425 aa)
	HCAG_04426	Rieske domain-containing protein. (563 aa)
	HCAG_04978	Uncharacterized protein. (665 aa)
	HCAG_05398	Prenylcys_lyase domain-containing protein. (558 aa)
	HCAG_05456	FAD_binding_3 domain-containing protein. (481 aa)
	HCAG_06641	Uncharacterized protein. (524 aa)
	HCAG_06862	FAD_binding_3 domain-containing protein. (465 aa)
	HCAG_06866	Uncharacterized protein. (613 aa)
	HCAG_05722	FAD_binding_3 domain-containing protein. (454 aa)
	HCAG_05871	Pyr_redox_2 domain-containing protein. (394 aa)
	HCAG_05915	Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (334 aa)
	HCAG_05923	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (595 aa)
	HCAG_06023	DAO domain-containing protein. (494 aa)
	HCAG_06236	GMC_OxRdtase_N domain-containing protein. (419 aa)
	HCAG_06297	DAO domain-containing protein. (436 aa)
	HCAG_06317	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (637 aa)
	HCAG_07019	Thioredoxin reductase. (324 aa)
	HCAG_07020	Uncharacterized protein. (1080 aa)
	HCAG_07244	Uncharacterized protein. (610 aa)
	HCAG_07561	FAD_binding_3 domain-containing protein. (419 aa)
	HCAG_07570	Uncharacterized protein. (821 aa)
	HCAG_07580	Uncharacterized protein. (701 aa)
	HCAG_07587	Uncharacterized protein. (644 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (510 aa)
	HCAG_07830	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (477 aa)
	HCAG_08156	GMC_OxRdtase_N domain-containing protein. (543 aa)
	HCAG_08164	FAD_binding_3 domain-containing protein. (455 aa)
	HCAG_08248	GIDA_assoc domain-containing protein. (673 aa)
	HCAG_08304	Uncharacterized protein. (631 aa)
	HCAG_08313	Pyr_redox_2 domain-containing protein. (455 aa)
	HCAG_08491	Uncharacterized protein; Belongs to the FMO family. (495 aa)
	HCAG_08670	Uncharacterized protein. (512 aa)
	HCAG_08825	Dihydrolipoyl dehydrogenase. (515 aa)
	HCAG_08907	FAD_binding_3 domain-containing protein. (376 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA4	HCAG_07561	A6RDT4	A6RD53	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	FAD_binding_3 domain-containing protein.	0.615
HCAG_00023	HCAG_01268	A6QRL7	A6QV61	GMC_OxRdtase_N domain-containing protein; Belongs to the GMC oxidoreductase family.	GMC_OxRdtase_N domain-containing protein.	0.513
HCAG_00023	HCAG_06236	A6QRL7	A6RB98	GMC_OxRdtase_N domain-containing protein; Belongs to the GMC oxidoreductase family.	GMC_OxRdtase_N domain-containing protein.	0.435
HCAG_00081	HCAG_00435	A6QRS5	A6QSS9	DAO domain-containing protein.	Pyr_redox_2 domain-containing protein.	0.436
HCAG_00081	HCAG_00787	A6QRS5	A6QTT1	DAO domain-containing protein.	DAO domain-containing protein.	0.530
HCAG_00081	HCAG_04426	A6QRS5	A6R468	DAO domain-containing protein.	Rieske domain-containing protein.	0.436
HCAG_00081	HCAG_06297	A6QRS5	A6RBF9	DAO domain-containing protein.	DAO domain-containing protein.	0.900
HCAG_00081	HCAG_08313	A6QRS5	A6RF97	DAO domain-containing protein.	Pyr_redox_2 domain-containing protein.	0.436
HCAG_00435	HCAG_00081	A6QSS9	A6QRS5	Pyr_redox_2 domain-containing protein.	DAO domain-containing protein.	0.436
HCAG_00435	HCAG_02219	A6QSS9	A6QXW2	Pyr_redox_2 domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.475
HCAG_00435	HCAG_05871	A6QSS9	A6RA83	Pyr_redox_2 domain-containing protein.	Pyr_redox_2 domain-containing protein.	0.410
HCAG_00435	HCAG_06297	A6QSS9	A6RBF9	Pyr_redox_2 domain-containing protein.	DAO domain-containing protein.	0.436
HCAG_00435	HCAG_07580	A6QSS9	A6RD72	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.436
HCAG_00435	HCAG_08825	A6QSS9	A6RGQ8	Pyr_redox_2 domain-containing protein.	Dihydrolipoyl dehydrogenase.	0.410
HCAG_00787	HCAG_00081	A6QTT1	A6QRS5	DAO domain-containing protein.	DAO domain-containing protein.	0.530
HCAG_00787	HCAG_02219	A6QTT1	A6QXW2	DAO domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.582
HCAG_00787	HCAG_05871	A6QTT1	A6RA83	DAO domain-containing protein.	Pyr_redox_2 domain-containing protein.	0.582
HCAG_00787	HCAG_06297	A6QTT1	A6RBF9	DAO domain-containing protein.	DAO domain-containing protein.	0.530
HCAG_00787	HCAG_07019	A6QTT1	A6RBL1	DAO domain-containing protein.	Thioredoxin reductase.	0.705
HCAG_00787	HCAG_07580	A6QTT1	A6RD72	DAO domain-containing protein.	Uncharacterized protein.	0.530