(11 nodes) Synthesis of PC network (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCAG_02051	Uncharacterized protein. (107 aa)
	HCAG_01984	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (197 aa)
	HCAG_01959	CTP_transf_like domain-containing protein. (533 aa)
	HCAG_01230	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (417 aa)
	HCAG_08223	AB hydrolase-1 domain-containing protein. (503 aa)
	HCAG_08173	Uncharacterized protein; Belongs to the CTL (choline transporter-like) family. (552 aa)
	HCAG_06402	DUF3074 domain-containing protein. (314 aa)
	HCAG_03790	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
	HCAG_03345	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (497 aa)
	HCAG_02361	Nuclear elongation and deformation protein 1. (746 aa)
	HCAG_02227	Choline_kin_N domain-containing protein. (811 aa)

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01230	HCAG_01959	A6QV23	A6QX52	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	CTP_transf_like domain-containing protein.	0.784
HCAG_01230	HCAG_01984	A6QV23	A6QX77	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.963
HCAG_01230	HCAG_02227	A6QV23	A6QXX0	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Choline_kin_N domain-containing protein.	0.607
HCAG_01230	HCAG_02361	A6QV23	A6QYA4	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Nuclear elongation and deformation protein 1.	0.941
HCAG_01959	HCAG_01230	A6QX52	A6QV23	CTP_transf_like domain-containing protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.784
HCAG_01959	HCAG_01984	A6QX52	A6QX77	CTP_transf_like domain-containing protein.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.537
HCAG_01959	HCAG_02227	A6QX52	A6QXX0	CTP_transf_like domain-containing protein.	Choline_kin_N domain-containing protein.	0.984
HCAG_01959	HCAG_02361	A6QX52	A6QYA4	CTP_transf_like domain-containing protein.	Nuclear elongation and deformation protein 1.	0.520
HCAG_01984	HCAG_01230	A6QX77	A6QV23	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.963
HCAG_01984	HCAG_01959	A6QX77	A6QX52	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	CTP_transf_like domain-containing protein.	0.537
HCAG_01984	HCAG_02227	A6QX77	A6QXX0	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	Choline_kin_N domain-containing protein.	0.510
HCAG_01984	HCAG_02361	A6QX77	A6QYA4	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	Nuclear elongation and deformation protein 1.	0.440
HCAG_02227	HCAG_01230	A6QXX0	A6QV23	Choline_kin_N domain-containing protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.607
HCAG_02227	HCAG_01959	A6QXX0	A6QX52	Choline_kin_N domain-containing protein.	CTP_transf_like domain-containing protein.	0.984
HCAG_02227	HCAG_01984	A6QXX0	A6QX77	Choline_kin_N domain-containing protein.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.510
HCAG_02227	HCAG_02361	A6QXX0	A6QYA4	Choline_kin_N domain-containing protein.	Nuclear elongation and deformation protein 1.	0.633
HCAG_02361	HCAG_01230	A6QYA4	A6QV23	Nuclear elongation and deformation protein 1.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.941
HCAG_02361	HCAG_01959	A6QYA4	A6QX52	Nuclear elongation and deformation protein 1.	CTP_transf_like domain-containing protein.	0.520
HCAG_02361	HCAG_01984	A6QYA4	A6QX77	Nuclear elongation and deformation protein 1.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.440
HCAG_02361	HCAG_02227	A6QYA4	A6QXX0	Nuclear elongation and deformation protein 1.	Choline_kin_N domain-containing protein.	0.633